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casticin  (MedChemExpress)


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    MedChemExpress casticin
    Casticin, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/casticin/product/MedChemExpress
    Average 94 stars, based on 5 article reviews
    casticin - by Bioz Stars, 2026-02
    94/100 stars

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    Bioactive compounds and nutraceuticals used for the management, treatment, or prevention of OA in humans.

    Journal: Pharmaceuticals

    Article Title: Nutritional Epigenomics: Bioactive Dietary Compounds in the Epigenetic Regulation of Osteoarthritis

    doi: 10.3390/ph17091148

    Figure Lengend Snippet: Bioactive compounds and nutraceuticals used for the management, treatment, or prevention of OA in humans.

    Article Snippet: Casticin (Vitexicarpin) , Vitex rotundifolia L. Polymethoxyflavonoid , Effects in IL-1β-induced OA chondrocytes: Prevented inflammation by inhibition of NF-κB signalling pathway Decreased NO, PGE2, TNF-α, IL-6, MMP-3, MMP-13, ADAMTS-4 and ADAMTS-5 production Inhibited NOS2 and COX2 mRNA and protein expression Increased ACAN and COL2A1 mRNA expression , [ ] .

    Techniques: Activation Assay, Derivative Assay, Expressing, Activity Assay, Inhibition, Membrane, Gene Expression, Phospho-proteomics, Translocation Assay, Functional Assay, Adjuvant, Comparison, Drug discovery, Modification, Solubility, Cannabis, Formulation, Marker, Control, Binding Assay, Sedimentation, Ex Vivo, In Vitro, Produced, Ubiquitin Proteomics, Concentration Assay, Clinical Proteomics