Review



ucb35625  (Tocris)


Bioz Verified Symbol Tocris is a verified supplier
Bioz Manufacturer Symbol Tocris manufactures this product  
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    Structured Review

    Tocris ucb35625
    Scheme 6. Selective inhibition of CCL2/7/8 production by bindarit, as well as blocking of CCR1 and CCR3 by selective (J113863, SB328437) or dual <t>(UCB35625)</t> antagonists, reduced even fully developed mechanical and thermal hypersensitivity in murine model of neuropathic pain.
    Ucb35625, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 15 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ucb35625/pm36611891-126-5-8?v=Tocris
    Average 93 stars, based on 15 article reviews
    ucb35625 - by Bioz Stars, 2026-07
    93/100 stars

    Images

    1) Product Images from "Pharmacological Evidence of the Important Roles of CCR1 and CCR3 and Their Endogenous Ligands CCL2/7/8 in Hypersensitivity Based on a Murine Model of Neuropathic Pain."

    Article Title: Pharmacological Evidence of the Important Roles of CCR1 and CCR3 and Their Endogenous Ligands CCL2/7/8 in Hypersensitivity Based on a Murine Model of Neuropathic Pain.

    Journal: Cells

    doi: 10.3390/cells12010098

    Scheme 6. Selective inhibition of CCL2/7/8 production by bindarit, as well as blocking of CCR1 and CCR3 by selective (J113863, SB328437) or dual (UCB35625) antagonists, reduced even fully developed mechanical and thermal hypersensitivity in murine model of neuropathic pain.
    Figure Legend Snippet: Scheme 6. Selective inhibition of CCL2/7/8 production by bindarit, as well as blocking of CCR1 and CCR3 by selective (J113863, SB328437) or dual (UCB35625) antagonists, reduced even fully developed mechanical and thermal hypersensitivity in murine model of neuropathic pain.

    Techniques Used: Inhibition, Blocking Assay



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    Scheme 6. Selective inhibition of CCL2/7/8 production by bindarit, as well as blocking of CCR1 and CCR3 by selective (J113863, SB328437) or dual <t>(UCB35625)</t> antagonists, reduced even fully developed mechanical and thermal hypersensitivity in murine model of neuropathic pain.
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    https://www.bioz.com/product/ucb35625/pm36611891-126-5-8?v=Tocris
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    Image Search Results


    Scheme 6. Selective inhibition of CCL2/7/8 production by bindarit, as well as blocking of CCR1 and CCR3 by selective (J113863, SB328437) or dual (UCB35625) antagonists, reduced even fully developed mechanical and thermal hypersensitivity in murine model of neuropathic pain.

    Journal: Cells

    Article Title: Pharmacological Evidence of the Important Roles of CCR1 and CCR3 and Their Endogenous Ligands CCL2/7/8 in Hypersensitivity Based on a Murine Model of Neuropathic Pain.

    doi: 10.3390/cells12010098

    Figure Lengend Snippet: Scheme 6. Selective inhibition of CCL2/7/8 production by bindarit, as well as blocking of CCR1 and CCR3 by selective (J113863, SB328437) or dual (UCB35625) antagonists, reduced even fully developed mechanical and thermal hypersensitivity in murine model of neuropathic pain.

    Article Snippet: Single Intrathecal Administration J113863, SB328437, UCB35625 and J113863+SB328437 (Tocris) were dissolved in 70% DMSO and administered once i.t. to operated male and female animals on the 12th day and post CCI at a dose of 20 μg/5 μL each.

    Techniques: Inhibition, Blocking Assay