Journal: Pharmaceutics
Article Title: Development and Characterization of EGCG-Loaded TPGS/Poloxamer 407 Micelles with Evaluation of In Vitro Drug Release and In Vivo Pharmacokinetics and Tolerability Observations Following Oral Administration
doi: 10.3390/pharmaceutics17111441
Figure Lengend Snippet: ( A ) Particle size ( B ) Polydispersity index (PDI) ( C ) Zeta potential ( D ) Encapsulation efficiency and ( E ) Drug loading capacity of different ratios of TPGS: Poloxamer 407. Parameters were measured in six replicates and presented as mean ± SEM. * p < 0.05 compared to ratio 3:1. ** p < 0.01 compared to ratio 3.1. *** p < 0.001 compared to ratio 3.1. ### p < 0.001 compared to ratio 2:2.
Article Snippet: EGCG (>94% purity), vitamin E TPGS, poloxamer 407 were procured from Taiyo Kagaku (Mie, Japan), MedChem Express (Monmouth Junction, NJ, USA) and Sigma-Aldrich (St. Louis, MO, USA), respectively.
Techniques: Zeta Potential Analyzer, Encapsulation