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rt112  (ATCC)


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    Structured Review

    ATCC rt112
    Rt112, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 758 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rt112/SV-HUC-1/pm42045965-85-1-8
    Average 97 stars, based on 758 article reviews
    rt112 - by Bioz Stars, 2026-11
    97/100 stars

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    Related Articles

    Cell Characterization:

    Article Title: Use of FGFR mutant gene panels in identifying cancer patients that will be responsive to treatment with an FGFR inhibitor
    Article Snippet: .. TABLE 12 Percent SW780 of Fusion-Positive RT112 FGFR3:BAIAP2L1 FGFR-fusion Cells vs FGFR3:TACC3v1 Average Ct Cell Count Background Average Ct (n = 2) (n = 2) Positive 1.00E+06 100% 17.56 20.35 Control 1000 0.1000% 27.95 28.61 500 0.0500% 29.11 28.91 250 0.0250% 29.62 30.14 125 0.0125% 30.26 31.43 62.5 0.0063% 31.19 31.69 LLOD 31.25 0.0031% 32.59 32.97 15.6 0.0016% 34.91 >40 0 0.0000% 0.00 >40 RT112 and SW780 = commercially available bladder cancer cell lines harboring the FGFR fusions (from American Type Culture Collection). ..

    Control:

    Article Title: Use of FGFR mutant gene panels in identifying cancer patients that will be responsive to treatment with an FGFR inhibitor
    Article Snippet: .. TABLE 12 Percent SW780 of Fusion-Positive RT112 FGFR3:BAIAP2L1 FGFR-fusion Cells vs FGFR3:TACC3v1 Average Ct Cell Count Background Average Ct (n = 2) (n = 2) Positive 1.00E+06 100% 17.56 20.35 Control 1000 0.1000% 27.95 28.61 500 0.0500% 29.11 28.91 250 0.0250% 29.62 30.14 125 0.0125% 30.26 31.43 62.5 0.0063% 31.19 31.69 LLOD 31.25 0.0031% 32.59 32.97 15.6 0.0016% 34.91 >40 0 0.0000% 0.00 >40 RT112 and SW780 = commercially available bladder cancer cell lines harboring the FGFR fusions (from American Type Culture Collection). ..

    other:

    Article Title: Association of SNPs in the PAI1 Gene with Disease Recurrence and Clinical Outcome in Bladder Cancer
    Article Snippet: Cell lines were obtained from the Pathology Core of the Bladder Cancer SPORE at MD Anderson Cancer Center (RT112, RT4, 5637, UM-UC-1, UM-UC-3, UM-UC-13, UM-UC-14, TCCSUP, 253-J, and 253J-BV cells), T24 cells from American Type Culture Collection (Manassas, VA, USA), and the UROtsa benign human bladder cell line from Dr. Donald Sens of the University of North Dakota School of Medicine, Grand Forks, ND.

    Article Title: ARID1A-deficient bladder cancer is dependent on PI3K signaling and sensitive to EZH2 and PI3K inhibitors
    Article Snippet: Bladder cancer cell lines HT1376 (RRID CVCL_1292), T24 (CVCL_0554), and 5637 (CVCL_0126) were obtained from ATCC, and RT112 (CVCL_1670) and VM-CUB1 (CVCL_1786) were obtained from DSMZ.

    Article Title: ARID1A-deficient bladder cancer is dependent on PI3K signaling and sensitive to EZH2 and PI3K inhibitors.
    Article Snippet: Bladder cancer cell lines HT1376 (RRID CVCL_1292), T24 (CVCL_0554), and 5637 (CVCL_0126) were obtained from ATCC, and RT112 (CVCL_1670) and VM-CUB1 (CVCL_1786) were obtained from DSMZ.



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    Effect of berbamine on 5-ALA-induced PpIX accumulation. <t>RT112,</t> RT112 LTT, RT112 CSC (top), and J82, J82 LTT, J82 CSC (bottom) were treated with 5-ALA (0–100 µg/ml) and berbamine (no, ½ IC 50 , IC 50 ). PpIX fluorescence intensity was normalized to cell viability and is shown as individual values with mean as a line. Asterisks indicate significance compared to the sample without berbamine (* p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001).
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    Image Search Results


    Effect of berbamine on 5-ALA-induced PpIX accumulation. RT112, RT112 LTT, RT112 CSC (top), and J82, J82 LTT, J82 CSC (bottom) were treated with 5-ALA (0–100 µg/ml) and berbamine (no, ½ IC 50 , IC 50 ). PpIX fluorescence intensity was normalized to cell viability and is shown as individual values with mean as a line. Asterisks indicate significance compared to the sample without berbamine (* p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001).

    Journal: Scientific Reports

    Article Title: Combining 5-ALA-PDT with berbamine as an in vitro multimodal therapy approach against bladder cancer cells

    doi: 10.1038/s41598-026-46092-x

    Figure Lengend Snippet: Effect of berbamine on 5-ALA-induced PpIX accumulation. RT112, RT112 LTT, RT112 CSC (top), and J82, J82 LTT, J82 CSC (bottom) were treated with 5-ALA (0–100 µg/ml) and berbamine (no, ½ IC 50 , IC 50 ). PpIX fluorescence intensity was normalized to cell viability and is shown as individual values with mean as a line. Asterisks indicate significance compared to the sample without berbamine (* p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001).

    Article Snippet: RT112 (DSMZ, cat. no. ACC-418) and J82 (ATCC, cat. no. HTB-1) cell lines originate from transitional cell carcinoma of the human bladder.

    Techniques: Fluorescence

    Cell viability of RT112, RT112 LTT and RT112 CSC following 5-ALA-PDT treatment with increasing irradiation doses and varying concentrations of 5-ALA and berbamine. Bars represent weighted means ± SD from three independent experiments ( n = 3 × 6; controls without irradiation n = 3 × 36). Asterisks indicate significance of unweighted means compared to the irradiated control sample without 5-ALA C1.1-C1.4 (* p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001).

    Journal: Scientific Reports

    Article Title: Combining 5-ALA-PDT with berbamine as an in vitro multimodal therapy approach against bladder cancer cells

    doi: 10.1038/s41598-026-46092-x

    Figure Lengend Snippet: Cell viability of RT112, RT112 LTT and RT112 CSC following 5-ALA-PDT treatment with increasing irradiation doses and varying concentrations of 5-ALA and berbamine. Bars represent weighted means ± SD from three independent experiments ( n = 3 × 6; controls without irradiation n = 3 × 36). Asterisks indicate significance of unweighted means compared to the irradiated control sample without 5-ALA C1.1-C1.4 (* p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001).

    Article Snippet: RT112 (DSMZ, cat. no. ACC-418) and J82 (ATCC, cat. no. HTB-1) cell lines originate from transitional cell carcinoma of the human bladder.

    Techniques: Irradiation, Control

    Berbamine has cytotoxic effects in ROS generation, cell migration and apoptosis rate for cisplatin-resistant cell lines RT112 LTT and J82 LTT. Tert-butyl hydroperoxide (TBHP; 150 µM) served as positive control for determination of reactive oxygen species (ROS). Detailed data presentation for all cell lines are available in the supplementary section (Supplementary Figs. , and ). Data represent mean ± SD ( n = 3). Asterisks indicate significance relative to the control without berbamine (* p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001).

    Journal: Scientific Reports

    Article Title: Combining 5-ALA-PDT with berbamine as an in vitro multimodal therapy approach against bladder cancer cells

    doi: 10.1038/s41598-026-46092-x

    Figure Lengend Snippet: Berbamine has cytotoxic effects in ROS generation, cell migration and apoptosis rate for cisplatin-resistant cell lines RT112 LTT and J82 LTT. Tert-butyl hydroperoxide (TBHP; 150 µM) served as positive control for determination of reactive oxygen species (ROS). Detailed data presentation for all cell lines are available in the supplementary section (Supplementary Figs. , and ). Data represent mean ± SD ( n = 3). Asterisks indicate significance relative to the control without berbamine (* p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001).

    Article Snippet: RT112 (DSMZ, cat. no. ACC-418) and J82 (ATCC, cat. no. HTB-1) cell lines originate from transitional cell carcinoma of the human bladder.

    Techniques: Migration, Positive Control, Control