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ptk7  (Proteintech)


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    Proteintech ptk7
    A. Summary table presenting the proteins identified and quantified by mass spectrometry analysis of ADAM10-KO cell lysates compared to control MCF7 cells and their corresponding secreted sEVs. B-C. sEVs secreted by MCF7 cells with knock-out of ADAM10 (A10 KO) or control cells (WT) were isolated by differential ultracentrifugation of conditioned culture media. Cell lysates and sEVs were analyzed by Western blot, testing for several proteins including EphrinB3, BCAM, E-cadherin and <t>PTK7</t> ( B ), SRC ( C ). Histograms represent mean signal intensities normalized to controls ± SEM, calculated from n independent experiments. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001, n.s. non-significant (multiple unpaired t-test).
    Ptk7, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 12 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ptk7/bio_rxiv__64898__2026__02__12__705562-132-48-49?v=Proteintech
    Average 93 stars, based on 12 article reviews
    ptk7 - by Bioz Stars, 2026-07
    93/100 stars

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    1) Product Images from "ADAM10 tailors extracellular vesicles for content transfer rather than signaling by contact"

    Article Title: ADAM10 tailors extracellular vesicles for content transfer rather than signaling by contact

    Journal: bioRxiv

    doi: 10.64898/2026.02.12.705562

    A. Summary table presenting the proteins identified and quantified by mass spectrometry analysis of ADAM10-KO cell lysates compared to control MCF7 cells and their corresponding secreted sEVs. B-C. sEVs secreted by MCF7 cells with knock-out of ADAM10 (A10 KO) or control cells (WT) were isolated by differential ultracentrifugation of conditioned culture media. Cell lysates and sEVs were analyzed by Western blot, testing for several proteins including EphrinB3, BCAM, E-cadherin and PTK7 ( B ), SRC ( C ). Histograms represent mean signal intensities normalized to controls ± SEM, calculated from n independent experiments. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001, n.s. non-significant (multiple unpaired t-test).
    Figure Legend Snippet: A. Summary table presenting the proteins identified and quantified by mass spectrometry analysis of ADAM10-KO cell lysates compared to control MCF7 cells and their corresponding secreted sEVs. B-C. sEVs secreted by MCF7 cells with knock-out of ADAM10 (A10 KO) or control cells (WT) were isolated by differential ultracentrifugation of conditioned culture media. Cell lysates and sEVs were analyzed by Western blot, testing for several proteins including EphrinB3, BCAM, E-cadherin and PTK7 ( B ), SRC ( C ). Histograms represent mean signal intensities normalized to controls ± SEM, calculated from n independent experiments. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001, n.s. non-significant (multiple unpaired t-test).

    Techniques Used: Mass Spectrometry, Control, Knock-Out, Isolation, Western Blot



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    Image Search Results


    A. Summary table presenting the proteins identified and quantified by mass spectrometry analysis of ADAM10-KO cell lysates compared to control MCF7 cells and their corresponding secreted sEVs. B-C. sEVs secreted by MCF7 cells with knock-out of ADAM10 (A10 KO) or control cells (WT) were isolated by differential ultracentrifugation of conditioned culture media. Cell lysates and sEVs were analyzed by Western blot, testing for several proteins including EphrinB3, BCAM, E-cadherin and PTK7 ( B ), SRC ( C ). Histograms represent mean signal intensities normalized to controls ± SEM, calculated from n independent experiments. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001, n.s. non-significant (multiple unpaired t-test).

    Journal: bioRxiv

    Article Title: ADAM10 tailors extracellular vesicles for content transfer rather than signaling by contact

    doi: 10.64898/2026.02.12.705562

    Figure Lengend Snippet: A. Summary table presenting the proteins identified and quantified by mass spectrometry analysis of ADAM10-KO cell lysates compared to control MCF7 cells and their corresponding secreted sEVs. B-C. sEVs secreted by MCF7 cells with knock-out of ADAM10 (A10 KO) or control cells (WT) were isolated by differential ultracentrifugation of conditioned culture media. Cell lysates and sEVs were analyzed by Western blot, testing for several proteins including EphrinB3, BCAM, E-cadherin and PTK7 ( B ), SRC ( C ). Histograms represent mean signal intensities normalized to controls ± SEM, calculated from n independent experiments. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001, n.s. non-significant (multiple unpaired t-test).

    Article Snippet: Antibodies directed against SDC1 intracellular domain (D4Y7H) was from (cell signaling #12922, dilution 1/1000), GFP (A11122) from Thermofisher (dilution 1/1000), ADAM17 (abcam, #ab39162, 1/1000 or cell signaling #3976, 1/1000), ADAM10 (abcam, #ab1997, 1/1 000), GAPDH (Proteintech # 10494-1-AP), Flotillin-1 (BD Biosciences, #X11669), Ephrin B3 (santa cruz, # sc-514139), PTK7 (Proteintech, #17799), E-cadherin (R&D Systems, #AF748), BCAM (R&D Systems, #BAF148), STAT3 124H6 (cell signaling #9139), p-STAT3 (cell signaling #9131).

    Techniques: Mass Spectrometry, Control, Knock-Out, Isolation, Western Blot