posaconazole (MedChemExpress)
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posaconazole
Posaconazole, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 15 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/posaconazole/Posaconazole/pmc13341599-158-10-25
Average 94 stars, based on 15 article reviews
Posaconazole, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 15 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/posaconazole/Posaconazole/pmc13341599-158-10-25
Average 94 stars, based on 15 article reviews
posaconazole - by Bioz Stars,
2026-09
94/100 stars
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1) Product Images from "In vitro synergistic activity of betulinic acid combined with azoles against pathogenic fungi"
Article Title: In vitro synergistic activity of betulinic acid combined with azoles against pathogenic fungi
Journal: Frontiers in Microbiology
doi: 10.3389/fmicb.2026.1835794
Figure Legend Snippet: Summary of drug interaction for the combination of BA and azoles. (A) Species–specific summary of interactions between BA–azole combinations and pathogenic fungi. (B) Azole–specific summary of interactions between BA–azole combinations and pathogenic fungi. (C) Isobologram analysis of the synergistic interaction between BA and POS. The X-axis represents normalized POS concentration, and the Y-axis represents normalized BA concentration. Normalized concentration was calculated as the MIC of the drug in combination divided by the MIC of the drug alone. The solid diagonal line represents the theoretical additive effect based on the Loewe additivity model. The upper and lower dashed lines indicate the 95% confidence intervals of the additive line. Each symbol corresponds to a different clinical isolate. Data points located below the lower 95% confidence line indicate synergistic activity. S, synergy (FICI≤0.5); I, indifference (FICI from >0.5 to ≤4); A, antagonism (FICI of >4); BA, betulinic acid; ITR, itraconazole; VOR, voriconazole; POS, posaconazole; FLC, fluconazole. The synergism rate was calculated by dividing the number of strains exhibiting synergism by the total number of strains tested.
Techniques Used: Concentration Assay, Activity Assay
Figure Legend Snippet: (A–Q) Detection of ROS levels after combined treatment with BA and POS; (R–U) Detection of ROS levels after combined treatment with BA and ITR. One–way ANOVA followed by Tukey’s HSD test was used for multiple group comparisons. POS, posaconazole; BA, betulinic acid; ns, p > 0.05; * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001.
Techniques Used:
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