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94
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Representative chromatograms of double blank sample, IS of each ATB, LLOQ of 11 ATBs (Caspofungin, CAS; Cefazolin, CFZ; Cefmetazole, CMZ; Imipenem, IPM; Linezolid, LZD; Latamoxef, MOX; Meropenem, MEM; <t>Posaconazole,</t> <t>POS;</t> Tigecycline, TIG; Piperacillin, PRL; Voriconazole, VCZ; Caspofungin Acetate-d4, CAS-d4; Linezolid-d3, LZD-d3; Meropenem-d6, MEM-d6; Piperacillin-d5, PER-d5; Voriconazole-d3, VCZ-d3).
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Representative chromatograms of double blank sample, IS of each ATB, LLOQ of 11 ATBs (Caspofungin, CAS; Cefazolin, CFZ; Cefmetazole, CMZ; Imipenem, IPM; Linezolid, LZD; Latamoxef, MOX; Meropenem, MEM; <t>Posaconazole,</t> <t>POS;</t> Tigecycline, TIG; Piperacillin, PRL; Voriconazole, VCZ; Caspofungin Acetate-d4, CAS-d4; Linezolid-d3, LZD-d3; Meropenem-d6, MEM-d6; Piperacillin-d5, PER-d5; Voriconazole-d3, VCZ-d3).
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Representative chromatograms of double blank sample, IS of each ATB, LLOQ of 11 ATBs (Caspofungin, CAS; Cefazolin, CFZ; Cefmetazole, CMZ; Imipenem, IPM; Linezolid, LZD; Latamoxef, MOX; Meropenem, MEM; <t>Posaconazole,</t> <t>POS;</t> Tigecycline, TIG; Piperacillin, PRL; Voriconazole, VCZ; Caspofungin Acetate-d4, CAS-d4; Linezolid-d3, LZD-d3; Meropenem-d6, MEM-d6; Piperacillin-d5, PER-d5; Voriconazole-d3, VCZ-d3).
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Representative chromatograms of double blank sample, IS of each ATB, LLOQ of 11 ATBs (Caspofungin, CAS; Cefazolin, CFZ; Cefmetazole, CMZ; Imipenem, IPM; Linezolid, LZD; Latamoxef, MOX; Meropenem, MEM; <t>Posaconazole,</t> <t>POS;</t> Tigecycline, TIG; Piperacillin, PRL; Voriconazole, VCZ; Caspofungin Acetate-d4, CAS-d4; Linezolid-d3, LZD-d3; Meropenem-d6, MEM-d6; Piperacillin-d5, PER-d5; Voriconazole-d3, VCZ-d3).
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MedChemExpress posaconazole
Representative chromatograms of double blank sample, IS of each ATB, LLOQ of 11 ATBs (Caspofungin, CAS; Cefazolin, CFZ; Cefmetazole, CMZ; Imipenem, IPM; Linezolid, LZD; Latamoxef, MOX; Meropenem, MEM; <t>Posaconazole,</t> <t>POS;</t> Tigecycline, TIG; Piperacillin, PRL; Voriconazole, VCZ; Caspofungin Acetate-d4, CAS-d4; Linezolid-d3, LZD-d3; Meropenem-d6, MEM-d6; Piperacillin-d5, PER-d5; Voriconazole-d3, VCZ-d3).
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Representative chromatograms of double blank sample, IS of each ATB, LLOQ of 11 ATBs (Caspofungin, CAS; Cefazolin, CFZ; Cefmetazole, CMZ; Imipenem, IPM; Linezolid, LZD; Latamoxef, MOX; Meropenem, MEM; <t>Posaconazole,</t> <t>POS;</t> Tigecycline, TIG; Piperacillin, PRL; Voriconazole, VCZ; Caspofungin Acetate-d4, CAS-d4; Linezolid-d3, LZD-d3; Meropenem-d6, MEM-d6; Piperacillin-d5, PER-d5; Voriconazole-d3, VCZ-d3).
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Representative chromatograms of double blank sample, IS of each ATB, LLOQ of 11 ATBs (Caspofungin, CAS; Cefazolin, CFZ; Cefmetazole, CMZ; Imipenem, IPM; Linezolid, LZD; Latamoxef, MOX; Meropenem, MEM; <t>Posaconazole,</t> <t>POS;</t> Tigecycline, TIG; Piperacillin, PRL; Voriconazole, VCZ; Caspofungin Acetate-d4, CAS-d4; Linezolid-d3, LZD-d3; Meropenem-d6, MEM-d6; Piperacillin-d5, PER-d5; Voriconazole-d3, VCZ-d3).
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Representative chromatograms of double blank sample, IS of each ATB, LLOQ of 11 ATBs (Caspofungin, CAS; Cefazolin, CFZ; Cefmetazole, CMZ; Imipenem, IPM; Linezolid, LZD; Latamoxef, MOX; Meropenem, MEM; Posaconazole, POS; Tigecycline, TIG; Piperacillin, PRL; Voriconazole, VCZ; Caspofungin Acetate-d4, CAS-d4; Linezolid-d3, LZD-d3; Meropenem-d6, MEM-d6; Piperacillin-d5, PER-d5; Voriconazole-d3, VCZ-d3).

Journal: Frontiers in Molecular Biosciences

Article Title: A validated LC-ESI-MS/MS assay for simultaneous plasma quantification of 11 antimicrobials to support personalized dosing in critically ill children

doi: 10.3389/fmolb.2026.1745458

Figure Lengend Snippet: Representative chromatograms of double blank sample, IS of each ATB, LLOQ of 11 ATBs (Caspofungin, CAS; Cefazolin, CFZ; Cefmetazole, CMZ; Imipenem, IPM; Linezolid, LZD; Latamoxef, MOX; Meropenem, MEM; Posaconazole, POS; Tigecycline, TIG; Piperacillin, PRL; Voriconazole, VCZ; Caspofungin Acetate-d4, CAS-d4; Linezolid-d3, LZD-d3; Meropenem-d6, MEM-d6; Piperacillin-d5, PER-d5; Voriconazole-d3, VCZ-d3).

Article Snippet: Posaconazole (POS) was purchased from LGC Standards (Molsheim, France).

Techniques: