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pdhb polyclonal antibody  (Proteintech)


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    Proteintech pdhb polyclonal antibody
    Pdhb Polyclonal Antibody, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 35 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pdhb/pm41702907-531-16-21?v=Proteintech
    Average 93 stars, based on 35 article reviews
    pdhb polyclonal antibody - by Bioz Stars, 2026-08
    93/100 stars

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    Effects of SLC on the expression of proteins within the PDK1/PDHA1 <t>and</t> <t>SIRT1/PGC-1α/NRF1/TFAM</t> signaling pathways on HCC1954 breast cancer cells. ( A ): PDK1, p-PDHA1, PDHA1and <t>PDHB</t> protein band under normoxic and hypoxic conditions; ( C , E ): PDH enzyme activity under normoxic and hypoxic conditions; ( B , D , G , H ): The protein relative expression was analyzed by Image J software; ( F ): NRF1, TFAM, SIRT1 and PGC1α protein band under normoxic and hypoxic conditions. N = 3 Compared with Ctrl group, * p < 0.05, ** p < 0.01, *** p < 0.001.
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    Effects of SLC on the expression of proteins within the PDK1/PDHA1 <t>and</t> <t>SIRT1/PGC-1α/NRF1/TFAM</t> signaling pathways on HCC1954 breast cancer cells. ( A ): PDK1, p-PDHA1, PDHA1and <t>PDHB</t> protein band under normoxic and hypoxic conditions; ( C , E ): PDH enzyme activity under normoxic and hypoxic conditions; ( B , D , G , H ): The protein relative expression was analyzed by Image J software; ( F ): NRF1, TFAM, SIRT1 and PGC1α protein band under normoxic and hypoxic conditions. N = 3 Compared with Ctrl group, * p < 0.05, ** p < 0.01, *** p < 0.001.
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    Effects of SLC on the expression of proteins within the PDK1/PDHA1 <t>and</t> <t>SIRT1/PGC-1α/NRF1/TFAM</t> signaling pathways on HCC1954 breast cancer cells. ( A ): PDK1, p-PDHA1, PDHA1and <t>PDHB</t> protein band under normoxic and hypoxic conditions; ( C , E ): PDH enzyme activity under normoxic and hypoxic conditions; ( B , D , G , H ): The protein relative expression was analyzed by Image J software; ( F ): NRF1, TFAM, SIRT1 and PGC1α protein band under normoxic and hypoxic conditions. N = 3 Compared with Ctrl group, * p < 0.05, ** p < 0.01, *** p < 0.001.
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    Image Search Results


    Effects of SLC on the expression of proteins within the PDK1/PDHA1 and SIRT1/PGC-1α/NRF1/TFAM signaling pathways on HCC1954 breast cancer cells. ( A ): PDK1, p-PDHA1, PDHA1and PDHB protein band under normoxic and hypoxic conditions; ( C , E ): PDH enzyme activity under normoxic and hypoxic conditions; ( B , D , G , H ): The protein relative expression was analyzed by Image J software; ( F ): NRF1, TFAM, SIRT1 and PGC1α protein band under normoxic and hypoxic conditions. N = 3 Compared with Ctrl group, * p < 0.05, ** p < 0.01, *** p < 0.001.

    Journal: International Journal of Molecular Sciences

    Article Title: Herbal Composition Inhibits Mitochondrial Oxidative Phosphorylation to Prevent HER2-Positive Breast Cancer and Identifies Potential Active Compounds

    doi: 10.3390/ijms262411970

    Figure Lengend Snippet: Effects of SLC on the expression of proteins within the PDK1/PDHA1 and SIRT1/PGC-1α/NRF1/TFAM signaling pathways on HCC1954 breast cancer cells. ( A ): PDK1, p-PDHA1, PDHA1and PDHB protein band under normoxic and hypoxic conditions; ( C , E ): PDH enzyme activity under normoxic and hypoxic conditions; ( B , D , G , H ): The protein relative expression was analyzed by Image J software; ( F ): NRF1, TFAM, SIRT1 and PGC1α protein band under normoxic and hypoxic conditions. N = 3 Compared with Ctrl group, * p < 0.05, ** p < 0.01, *** p < 0.001.

    Article Snippet: PDK1 (Abcam, Cambridge, UK, Ab207450 ), p-PDHA1 (Abcam, ab177461), PDHA1 (Abcam, ab168379), AKT (Proteintech, Rosemont, IL, USA, 10176-2-AP), p-AKT (S308) (CST, 13038T), ERK (Proteintech, 11257-1-AP), p-ERK (Thr202) (CST, 4370T), AKT (Proteintech, 10176-2-AP), p-HER2/ErbB2 (Tyr1221/1222) (CST, 2243T), HER2/ErbB2(CST,4290T), SIRT1 (Proteintech, 60303-1-Ig), PDHB (Proteintech, 14744-1-Ap), PGC-1α (CST, 2178s), NRF-1 (Proteintech, 12482-1-Ap), TFAM (Proteintech, 22568-1-AP).

    Techniques: Expressing, Protein-Protein interactions, Activity Assay, Software

    SLC inhibited PDK1 to induce cell apoptosis in HER2-positive HCC1954 breast cancer cells. ( A ). The protein expression of PDK1, PDHA1 and PDHB after overexpression of PDK1; ( B , C ). The analysis of WB band by Image Lab software. ( D ). SLC induces cell apoptosis after overexpression of PDK1 by flow cytometry; ( E ). The flow data analysis by flowjo10.0 software. N = 3. Compared with Ctrl group, * p < 0.05, ** p < 0.01. Compared with PDK1 overexpress group, # p < 0.05, ## p < 0.01.

    Journal: International Journal of Molecular Sciences

    Article Title: Herbal Composition Inhibits Mitochondrial Oxidative Phosphorylation to Prevent HER2-Positive Breast Cancer and Identifies Potential Active Compounds

    doi: 10.3390/ijms262411970

    Figure Lengend Snippet: SLC inhibited PDK1 to induce cell apoptosis in HER2-positive HCC1954 breast cancer cells. ( A ). The protein expression of PDK1, PDHA1 and PDHB after overexpression of PDK1; ( B , C ). The analysis of WB band by Image Lab software. ( D ). SLC induces cell apoptosis after overexpression of PDK1 by flow cytometry; ( E ). The flow data analysis by flowjo10.0 software. N = 3. Compared with Ctrl group, * p < 0.05, ** p < 0.01. Compared with PDK1 overexpress group, # p < 0.05, ## p < 0.01.

    Article Snippet: PDK1 (Abcam, Cambridge, UK, Ab207450 ), p-PDHA1 (Abcam, ab177461), PDHA1 (Abcam, ab168379), AKT (Proteintech, Rosemont, IL, USA, 10176-2-AP), p-AKT (S308) (CST, 13038T), ERK (Proteintech, 11257-1-AP), p-ERK (Thr202) (CST, 4370T), AKT (Proteintech, 10176-2-AP), p-HER2/ErbB2 (Tyr1221/1222) (CST, 2243T), HER2/ErbB2(CST,4290T), SIRT1 (Proteintech, 60303-1-Ig), PDHB (Proteintech, 14744-1-Ap), PGC-1α (CST, 2178s), NRF-1 (Proteintech, 12482-1-Ap), TFAM (Proteintech, 22568-1-AP).

    Techniques: Expressing, Over Expression, Software, Flow Cytometry