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gossypol acetic acid  (MedChemExpress)


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    Structured Review

    MedChemExpress gossypol acetic acid
    Gossypol Acetic Acid, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/gossypol/Gossypol/pm42537886-34-0-15
    Average 94 stars, based on 5 article reviews
    gossypol acetic acid - by Bioz Stars, 2026-09
    94/100 stars

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    Related Articles

    In Vitro:

    Article Title: Effects of Gossypol Exposure on Ovarian Reserve Function: Comprehensive Risk Assessment Based on TRAEC Strategy
    Article Snippet: .. 1 , Su et al., 2025 [ ] , China , 44 h , Oocytes , Porcine ovaries , Gossypol (purity >99%, MedChemExpress, Princeton, NJ, USA) , 10, 20, and 40 μM gossypol , Gossypol impaired porcine oocyte maturation in vitro by reducing PB1 extrusion, inhibiting cumulus expansion, and disrupting meiosis.. ..

    Indirect Immunoperoxidase Assay:

    Article Title: Lactiplantibacillus plantarum attenuate gossypol-induced hepatic lipotoxicity by altering intestinal microbiota for enriching microbial tryptophan metabolites in Nile tilapia ( Oreochromis niloticus )
    Article Snippet: Hepatocytes were harvested by centrifuging at 850× g for 10 min. Red blood cells were removed with a red cell lysis buffer (RT122-02, Tiangen, Beijing, China), and the remaining cells were incubated in DMEM containing 10% FBS and 1% penicillin–streptomycin at 28 °C in a cell culture incubator. .. To investigate the effect of indole-3-propionic acid (IPA) on FFAs esterification, primary hepatocytes were treated with 40 μM gossypol and different concentrations of IPA (50 μM, 100 μM, 200 μM) for 24 h. To determine whether Ahr is the key factor affecting FFAs esterification, primary hepatocytes were treated with gossypol (40 μM), gossypol + 200 μM IPA or gossypol + 200 μM IPA + 1 μM BAY-218 (Ahr inhibitor, HY-11449, MCE, USA) for 24 h. For the detection of lipid droplets, cells were stained with 10 μg/mL BODIPY 493/503 (D3922, Invitrogen, USA) at room temperature for 30 min and then imaged using Nikon Ds Ri2, Japan fluorescence microscope. ..

    Staining:

    Article Title: Lactiplantibacillus plantarum attenuate gossypol-induced hepatic lipotoxicity by altering intestinal microbiota for enriching microbial tryptophan metabolites in Nile tilapia ( Oreochromis niloticus )
    Article Snippet: Hepatocytes were harvested by centrifuging at 850× g for 10 min. Red blood cells were removed with a red cell lysis buffer (RT122-02, Tiangen, Beijing, China), and the remaining cells were incubated in DMEM containing 10% FBS and 1% penicillin–streptomycin at 28 °C in a cell culture incubator. .. To investigate the effect of indole-3-propionic acid (IPA) on FFAs esterification, primary hepatocytes were treated with 40 μM gossypol and different concentrations of IPA (50 μM, 100 μM, 200 μM) for 24 h. To determine whether Ahr is the key factor affecting FFAs esterification, primary hepatocytes were treated with gossypol (40 μM), gossypol + 200 μM IPA or gossypol + 200 μM IPA + 1 μM BAY-218 (Ahr inhibitor, HY-11449, MCE, USA) for 24 h. For the detection of lipid droplets, cells were stained with 10 μg/mL BODIPY 493/503 (D3922, Invitrogen, USA) at room temperature for 30 min and then imaged using Nikon Ds Ri2, Japan fluorescence microscope. ..

    Fluorescence:

    Article Title: Lactiplantibacillus plantarum attenuate gossypol-induced hepatic lipotoxicity by altering intestinal microbiota for enriching microbial tryptophan metabolites in Nile tilapia ( Oreochromis niloticus )
    Article Snippet: Hepatocytes were harvested by centrifuging at 850× g for 10 min. Red blood cells were removed with a red cell lysis buffer (RT122-02, Tiangen, Beijing, China), and the remaining cells were incubated in DMEM containing 10% FBS and 1% penicillin–streptomycin at 28 °C in a cell culture incubator. .. To investigate the effect of indole-3-propionic acid (IPA) on FFAs esterification, primary hepatocytes were treated with 40 μM gossypol and different concentrations of IPA (50 μM, 100 μM, 200 μM) for 24 h. To determine whether Ahr is the key factor affecting FFAs esterification, primary hepatocytes were treated with gossypol (40 μM), gossypol + 200 μM IPA or gossypol + 200 μM IPA + 1 μM BAY-218 (Ahr inhibitor, HY-11449, MCE, USA) for 24 h. For the detection of lipid droplets, cells were stained with 10 μg/mL BODIPY 493/503 (D3922, Invitrogen, USA) at room temperature for 30 min and then imaged using Nikon Ds Ri2, Japan fluorescence microscope. ..

    Microscopy:

    Article Title: Lactiplantibacillus plantarum attenuate gossypol-induced hepatic lipotoxicity by altering intestinal microbiota for enriching microbial tryptophan metabolites in Nile tilapia ( Oreochromis niloticus )
    Article Snippet: Hepatocytes were harvested by centrifuging at 850× g for 10 min. Red blood cells were removed with a red cell lysis buffer (RT122-02, Tiangen, Beijing, China), and the remaining cells were incubated in DMEM containing 10% FBS and 1% penicillin–streptomycin at 28 °C in a cell culture incubator. .. To investigate the effect of indole-3-propionic acid (IPA) on FFAs esterification, primary hepatocytes were treated with 40 μM gossypol and different concentrations of IPA (50 μM, 100 μM, 200 μM) for 24 h. To determine whether Ahr is the key factor affecting FFAs esterification, primary hepatocytes were treated with gossypol (40 μM), gossypol + 200 μM IPA or gossypol + 200 μM IPA + 1 μM BAY-218 (Ahr inhibitor, HY-11449, MCE, USA) for 24 h. For the detection of lipid droplets, cells were stained with 10 μg/mL BODIPY 493/503 (D3922, Invitrogen, USA) at room temperature for 30 min and then imaged using Nikon Ds Ri2, Japan fluorescence microscope. ..

    other:

    Article Title: Melatonin protects porcine oocytes from gossypol-induced meiosis defects via regulation of SIRT1-mediated mitophagy.
    Article Snippet: Cottonseed meal (CSM) is an ideal source of protein feed ingredients.. However, the gossypol contained in it has toxic effects on animals, limiting its use in livestock production.. The underlying mechanisms remain largely unknown.

    Injection:

    Article Title: Morinda officinalis oligosaccharides improves sperm motility via the gut microbiota and the IGF-1/PI3K/mTOR signaling pathway
    Article Snippet: MOS was purchased from Beijing Tongrentang Company Limited (Lot No. 2021B03527; 0.3 g per capsule; MOS 150 mg per capsule). .. Asthenozoospermia was induced by intraperitoneal injection of gossypol (20 mg/kg; HY-13407, Medchemexpress) every 3 days for 30 days, as previously reported ( ); controls received equal volumes of 0.9% NaCl. ..



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