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genechip microarray analysis suite  (Thermo Fisher)


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    Structured Review

    Thermo Fisher genechip microarray analysis suite
    Genechip Microarray Analysis Suite, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/genechip+microarray+analysis/genechip+microarray+analysis+suite/pm39812341-61-0-1
    Average 90 stars, based on 1 article reviews
    genechip microarray analysis suite - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Microarray:

    Article Title: Long Noncoding RNAs in the Pathogenesis of Insulin Resistance.
    Article Snippet: .. Affymetrix GeneChip microarray analysis in SRA overexpressing ST2 adipocytes and SRA knockdown 3T3-L1 adipocytes revealed that SRA regulated insulin sensitivity and insulin-stimulated glucose uptake, and inhibited TNFα signaling in adipocytes [227]. ..

    Article Title: Gene Profile of Myeloid-Derived Suppressive Cells from the Bone Marrow of Lysosomal Acid Lipase Knock-Out Mice
    Article Snippet: .. For example, although up-regulation of Stats family members was not detected by Affymetrix GeneChip microarray analysis, phosphorylation of Stat3 at Y705 has been detected in expanded lal−/− MDSCs . ..

    Article Title: Long non-coding RNA ncRuPAR regulates gastric cancer cell proliferation and apoptosis via phosphoinositide 3-kinase/protein kinase B signaling.
    Article Snippet: .. Differentially expressed genes in HGC-27-ncRuPAR overexpression and HGC-27-empty vector cell lines were identified using Affymetrix GeneChip microarray analysis. ..

    Article Title: MiR-196a Promotes Pancreatic Cancer Progression by Targeting Nuclear Factor Kappa-B-Inhibitor Alpha
    Article Snippet: .. The miRNA gene expression profile of four human pancreatic cancer cell lines and H6C7 was determined by GeneChip microarray analysis (Affymetrix, Santa Clare, CA, USA). ..

    Article Title: Gene Profile of Myeloid-Derived Suppressive Cells from the Bone Marrow of Lysosomal Acid Lipase Knock-Out Mice
    Article Snippet: .. Affymetrix GeneChip microarray analysis identified detailed intrinsic defects in Ly6G + myeloid lineage cells of LAL knock-out ( lal−/− ) mice. ..

    Article Title: SCUBE3 downregulation modulates hepatocellular carcinoma by inhibiting CCNE1 via TGFβ/PI3K/AKT/GSK3β pathway
    Article Snippet: .. To verify how SCUBE3 promotes the proliferation of liver cancer cells through CCNE1, we first applied KEGG enrichment analysis on the DEGs in the classical pathway screened by Affymetrix GeneChip microarray analysis (Fig. B). ..

    Article Title: SCUBE3 downregulation modulates hepatocellular carcinoma by inhibiting CCNE1 via TGFβ/PI3K/AKT/GSK3β pathway
    Article Snippet: .. To explore the underlying molecular biochemical mechanisms, 894 DEGs in SCUBE3-KD and SCUBE3-NC groups were screened by using Affymetrix GeneChip microarray analysis (Fig. ). ..

    Article Title: SCUBE3 downregulation modulates hepatocellular carcinoma by inhibiting CCNE1 via TGFβ/PI3K/AKT/GSK3β pathway
    Article Snippet: .. To further investigate the molecular mechanism underlying the SCUBE3-mediated promotion of HCC cell proliferation, total RNA of cells was extracted to apply RNA-Seq analysis, and then the Affymetrix GeneChip microarray analysis was used to screen and identify differentially expressed genes (DEGs). ..

    Knockdown:

    Article Title: Long Noncoding RNAs in the Pathogenesis of Insulin Resistance.
    Article Snippet: .. Affymetrix GeneChip microarray analysis in SRA overexpressing ST2 adipocytes and SRA knockdown 3T3-L1 adipocytes revealed that SRA regulated insulin sensitivity and insulin-stimulated glucose uptake, and inhibited TNFα signaling in adipocytes [227]. ..

    Phospho-proteomics:

    Article Title: Gene Profile of Myeloid-Derived Suppressive Cells from the Bone Marrow of Lysosomal Acid Lipase Knock-Out Mice
    Article Snippet: .. For example, although up-regulation of Stats family members was not detected by Affymetrix GeneChip microarray analysis, phosphorylation of Stat3 at Y705 has been detected in expanded lal−/− MDSCs . ..

    Over Expression:

    Article Title: Long non-coding RNA ncRuPAR regulates gastric cancer cell proliferation and apoptosis via phosphoinositide 3-kinase/protein kinase B signaling.
    Article Snippet: .. Differentially expressed genes in HGC-27-ncRuPAR overexpression and HGC-27-empty vector cell lines were identified using Affymetrix GeneChip microarray analysis. ..

    Plasmid Preparation:

    Article Title: Long non-coding RNA ncRuPAR regulates gastric cancer cell proliferation and apoptosis via phosphoinositide 3-kinase/protein kinase B signaling.
    Article Snippet: .. Differentially expressed genes in HGC-27-ncRuPAR overexpression and HGC-27-empty vector cell lines were identified using Affymetrix GeneChip microarray analysis. ..

    Gene Expression:

    Article Title: MiR-196a Promotes Pancreatic Cancer Progression by Targeting Nuclear Factor Kappa-B-Inhibitor Alpha
    Article Snippet: .. The miRNA gene expression profile of four human pancreatic cancer cell lines and H6C7 was determined by GeneChip microarray analysis (Affymetrix, Santa Clare, CA, USA). ..

    Knock-Out:

    Article Title: Gene Profile of Myeloid-Derived Suppressive Cells from the Bone Marrow of Lysosomal Acid Lipase Knock-Out Mice
    Article Snippet: .. Affymetrix GeneChip microarray analysis identified detailed intrinsic defects in Ly6G + myeloid lineage cells of LAL knock-out ( lal−/− ) mice. ..

    RNA sequencing:

    Article Title: SCUBE3 downregulation modulates hepatocellular carcinoma by inhibiting CCNE1 via TGFβ/PI3K/AKT/GSK3β pathway
    Article Snippet: .. To further investigate the molecular mechanism underlying the SCUBE3-mediated promotion of HCC cell proliferation, total RNA of cells was extracted to apply RNA-Seq analysis, and then the Affymetrix GeneChip microarray analysis was used to screen and identify differentially expressed genes (DEGs). ..



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    Image Search Results


    Graphs showing the representative transcripts of genes related to vitamin A metabolism in qRT-PCR. QRT-PCR was also performed for the genes AKR1B15, RDH12, AKR1B10, and CRABP2, which are upregulated more than twentyfold among the significantly upregulated genes and promote binding to RAR, two genes (RARB and RARRES3) whose expression was downregulated more than 1/50, and RARA and RARG, which are other types of RAR. By normalizing the expression of the gene of interest to the expression of 18S rRNA, we were able to obtain a relative measure of the expression level of each gene (* P < 0.05, ** P < 0.005, *** P < 0.0005). Similar to the microarray results, RARB, CRABP2, and RARRES3 showed significant differences, whereas RARA and RARG showed no significant differences.

    Journal: Investigative Ophthalmology & Visual Science

    Article Title: Alteration of Gene Expression in Pathological Keratinization of the Ocular Surface

    doi: 10.1167/iovs.65.6.37

    Figure Lengend Snippet: Graphs showing the representative transcripts of genes related to vitamin A metabolism in qRT-PCR. QRT-PCR was also performed for the genes AKR1B15, RDH12, AKR1B10, and CRABP2, which are upregulated more than twentyfold among the significantly upregulated genes and promote binding to RAR, two genes (RARB and RARRES3) whose expression was downregulated more than 1/50, and RARA and RARG, which are other types of RAR. By normalizing the expression of the gene of interest to the expression of 18S rRNA, we were able to obtain a relative measure of the expression level of each gene (* P < 0.05, ** P < 0.005, *** P < 0.0005). Similar to the microarray results, RARB, CRABP2, and RARRES3 showed significant differences, whereas RARA and RARG showed no significant differences.

    Article Snippet: Microarray experiments were then performed according to the protocols provided by Thermo Fisher Scientific, and scanned microarray images were obtained using the GeneChip Scanner 3000 7G (Thermo Fisher Scientific) microarray analysis system.

    Techniques: Quantitative RT-PCR, Binding Assay, Expressing, Microarray