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cab  (MedChemExpress)


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    MedChemExpress cab
    Cab, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 10 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cab/product/MedChemExpress
    Average 93 stars, based on 10 article reviews
    cab - by Bioz Stars, 2026-06
    93/100 stars

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    Time-response data (A, C) and quantification by area under the time course curves (B, D) showing the effects of dopaminergic D1-like receptor agonists CY 208-243 (A, B) or D2-like receptor agonist <t>cabergoline</t> (C, D) on analgesic response to morphine in tolerant animals. Each agonist was microinjected into the NAc 5 minutes prior to the morphine administration. Data are presented as a mean ± SEM of 6 rats. NAc: nucleus accumbens, inj.: injection, BL: baseline value, AUC: area under the course curve, SEM: standard error of the mean. * P < 0.001 compared to the vehicle group.
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    Time-response data (A, C) and quantification by area under the time course curves (B, D) showing the effects of dopaminergic D1-like receptor agonists CY 208-243 (A, B) or D2-like receptor agonist cabergoline (C, D) on analgesic response to morphine in tolerant animals. Each agonist was microinjected into the NAc 5 minutes prior to the morphine administration. Data are presented as a mean ± SEM of 6 rats. NAc: nucleus accumbens, inj.: injection, BL: baseline value, AUC: area under the course curve, SEM: standard error of the mean. * P < 0.001 compared to the vehicle group.

    Journal: The Korean Journal of Pain

    Article Title: The role of nucleus accumbens dopamine signaling in the development of morphine tolerance in neuropathic pain

    doi: 10.3344/kjp.25327

    Figure Lengend Snippet: Time-response data (A, C) and quantification by area under the time course curves (B, D) showing the effects of dopaminergic D1-like receptor agonists CY 208-243 (A, B) or D2-like receptor agonist cabergoline (C, D) on analgesic response to morphine in tolerant animals. Each agonist was microinjected into the NAc 5 minutes prior to the morphine administration. Data are presented as a mean ± SEM of 6 rats. NAc: nucleus accumbens, inj.: injection, BL: baseline value, AUC: area under the course curve, SEM: standard error of the mean. * P < 0.001 compared to the vehicle group.

    Article Snippet: The following drugs were used in the current study: morphine (BCWORLD Pharm) dissolved in saline, CY 208-243 (1 μg; Tocris Cookson Ltd.), a selective D1-like receptor agonist, and cabergoline (0.1 μg; Tocris Cookson Ltd.), a selective D2-like receptor agonist dissolved in 70% DMSO (dimethyl sulfoxide).

    Techniques: Injection