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alchivemycin  (Difco)

 
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    Structured Review

    Difco alchivemycin
    Production of a novel antibiotic, alchivemycin A, in a combined culture of Streptomyces endus S-522 and T. pulmonis or C. glutamicum. Shown is the production of <t>alchivemycin</t> <t>A</t> in a combined culture of S. endus S-522 and T. pulmonis or C. glutamicum. (A to D) HPLC profiles of the secondary metabolites produced by S-522 cultured with or without T. pulmonis. Shown are the culture broths of the combined culture with T. pulmonis (A), combined culture with C. glutamicum (B), S-522 pure culture (C), and T. pulmonis pure culture (D). The arrow shows the peak for alchivemycin A. Elution was performed with a linear gradient, as indicated on the scale at the right. (E) Chemical structure of alchivemycin A.
    Alchivemycin, supplied by Difco, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/alchivemycin/alchivemycin/pmc03020563-327-35-94
    Average 90 stars, based on 1 article reviews
    alchivemycin - by Bioz Stars, 2026-10
    90/100 stars

    Images

    1) Product Images from "Mycolic Acid-Containing Bacteria Induce Natural-Product Biosynthesis in Streptomyces Species ▿ † "

    Article Title: Mycolic Acid-Containing Bacteria Induce Natural-Product Biosynthesis in Streptomyces Species ▿ †

    Journal: Applied and Environmental Microbiology

    doi: 10.1128/AEM.01337-10

    Production of a novel antibiotic, alchivemycin A, in a combined culture of Streptomyces endus S-522 and T. pulmonis or C. glutamicum. Shown is the production of alchivemycin A in a combined culture of S. endus S-522 and T. pulmonis or C. glutamicum. (A to D) HPLC profiles of the secondary metabolites produced by S-522 cultured with or without T. pulmonis. Shown are the culture broths of the combined culture with T. pulmonis (A), combined culture with C. glutamicum (B), S-522 pure culture (C), and T. pulmonis pure culture (D). The arrow shows the peak for alchivemycin A. Elution was performed with a linear gradient, as indicated on the scale at the right. (E) Chemical structure of alchivemycin A.
    Figure Legend Snippet: Production of a novel antibiotic, alchivemycin A, in a combined culture of Streptomyces endus S-522 and T. pulmonis or C. glutamicum. Shown is the production of alchivemycin A in a combined culture of S. endus S-522 and T. pulmonis or C. glutamicum. (A to D) HPLC profiles of the secondary metabolites produced by S-522 cultured with or without T. pulmonis. Shown are the culture broths of the combined culture with T. pulmonis (A), combined culture with C. glutamicum (B), S-522 pure culture (C), and T. pulmonis pure culture (D). The arrow shows the peak for alchivemycin A. Elution was performed with a linear gradient, as indicated on the scale at the right. (E) Chemical structure of alchivemycin A.

    Techniques Used: Produced, Cell Culture

    Antibacterial activities of alchivemycin A a
    Figure Legend Snippet: Antibacterial activities of alchivemycin A a

    Techniques Used:

    Related Articles

    Activity Assay:

    Article Title: Mycolic Acid-Containing Bacteria Induce Natural-Product Biosynthesis in Streptomyces Species
    Article Snippet: .. This antibiotic contains a heterocyclic chromophore that has not been described previously and shows specific antibiotic activity against Micrococcus luteus at a concentration of 0.06 μg/ml (Table ). table ft1 table-wrap mode="anchored" t5 TABLE 3. caption a7 Organism Relevant characteristic Alchivemycin A MIC (μg/ml) Micrococcus luteus Gram positive 0.06 Bacillus subtilis Gram positive 40 Staphylococcus aureus Gram positive >50 Escherichia coli Gram negative >50 Saccharomyces cerevisiae Yeast cell >50 Candida albicans Yeast cell >50 Open in a separate window a The MICs were determined by the 2-fold sequential dilution method in heart infusion broth (Difco). ..

    Concentration Assay:

    Article Title: Mycolic Acid-Containing Bacteria Induce Natural-Product Biosynthesis in Streptomyces Species
    Article Snippet: .. This antibiotic contains a heterocyclic chromophore that has not been described previously and shows specific antibiotic activity against Micrococcus luteus at a concentration of 0.06 μg/ml (Table ). table ft1 table-wrap mode="anchored" t5 TABLE 3. caption a7 Organism Relevant characteristic Alchivemycin A MIC (μg/ml) Micrococcus luteus Gram positive 0.06 Bacillus subtilis Gram positive 40 Staphylococcus aureus Gram positive >50 Escherichia coli Gram negative >50 Saccharomyces cerevisiae Yeast cell >50 Candida albicans Yeast cell >50 Open in a separate window a The MICs were determined by the 2-fold sequential dilution method in heart infusion broth (Difco). ..



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    Production of a novel antibiotic, alchivemycin A, in a combined culture of Streptomyces endus S-522 and T. pulmonis or C. glutamicum. Shown is the production of <t>alchivemycin</t> <t>A</t> in a combined culture of S. endus S-522 and T. pulmonis or C. glutamicum. (A to D) HPLC profiles of the secondary metabolites produced by S-522 cultured with or without T. pulmonis. Shown are the culture broths of the combined culture with T. pulmonis (A), combined culture with C. glutamicum (B), S-522 pure culture (C), and T. pulmonis pure culture (D). The arrow shows the peak for alchivemycin A. Elution was performed with a linear gradient, as indicated on the scale at the right. (E) Chemical structure of alchivemycin A.
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    Image Search Results


    Production of a novel antibiotic, alchivemycin A, in a combined culture of Streptomyces endus S-522 and T. pulmonis or C. glutamicum. Shown is the production of alchivemycin A in a combined culture of S. endus S-522 and T. pulmonis or C. glutamicum. (A to D) HPLC profiles of the secondary metabolites produced by S-522 cultured with or without T. pulmonis. Shown are the culture broths of the combined culture with T. pulmonis (A), combined culture with C. glutamicum (B), S-522 pure culture (C), and T. pulmonis pure culture (D). The arrow shows the peak for alchivemycin A. Elution was performed with a linear gradient, as indicated on the scale at the right. (E) Chemical structure of alchivemycin A.

    Journal: Applied and Environmental Microbiology

    Article Title: Mycolic Acid-Containing Bacteria Induce Natural-Product Biosynthesis in Streptomyces Species ▿ †

    doi: 10.1128/AEM.01337-10

    Figure Lengend Snippet: Production of a novel antibiotic, alchivemycin A, in a combined culture of Streptomyces endus S-522 and T. pulmonis or C. glutamicum. Shown is the production of alchivemycin A in a combined culture of S. endus S-522 and T. pulmonis or C. glutamicum. (A to D) HPLC profiles of the secondary metabolites produced by S-522 cultured with or without T. pulmonis. Shown are the culture broths of the combined culture with T. pulmonis (A), combined culture with C. glutamicum (B), S-522 pure culture (C), and T. pulmonis pure culture (D). The arrow shows the peak for alchivemycin A. Elution was performed with a linear gradient, as indicated on the scale at the right. (E) Chemical structure of alchivemycin A.

    Article Snippet: This antibiotic contains a heterocyclic chromophore that has not been described previously and shows specific antibiotic activity against Micrococcus luteus at a concentration of 0.06 μg/ml (Table ). table ft1 table-wrap mode="anchored" t5 TABLE 3. caption a7 Organism Relevant characteristic Alchivemycin A MIC (μg/ml) Micrococcus luteus Gram positive 0.06 Bacillus subtilis Gram positive 40 Staphylococcus aureus Gram positive >50 Escherichia coli Gram negative >50 Saccharomyces cerevisiae Yeast cell >50 Candida albicans Yeast cell >50 Open in a separate window a The MICs were determined by the 2-fold sequential dilution method in heart infusion broth (Difco).

    Techniques: Produced, Cell Culture

    Antibacterial activities of alchivemycin A a

    Journal: Applied and Environmental Microbiology

    Article Title: Mycolic Acid-Containing Bacteria Induce Natural-Product Biosynthesis in Streptomyces Species ▿ †

    doi: 10.1128/AEM.01337-10

    Figure Lengend Snippet: Antibacterial activities of alchivemycin A a

    Article Snippet: This antibiotic contains a heterocyclic chromophore that has not been described previously and shows specific antibiotic activity against Micrococcus luteus at a concentration of 0.06 μg/ml (Table ). table ft1 table-wrap mode="anchored" t5 TABLE 3. caption a7 Organism Relevant characteristic Alchivemycin A MIC (μg/ml) Micrococcus luteus Gram positive 0.06 Bacillus subtilis Gram positive 40 Staphylococcus aureus Gram positive >50 Escherichia coli Gram negative >50 Saccharomyces cerevisiae Yeast cell >50 Candida albicans Yeast cell >50 Open in a separate window a The MICs were determined by the 2-fold sequential dilution method in heart infusion broth (Difco).

    Techniques: