precursor fapi (MedChemExpress)
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MedChemExpress
precursor fapi
![Radiochemical stability assessment of [ 68 <t>Ga]Ga-FAPi-46</t> in ( A ) saline solution (room temperature) and ( B ) human serum (37 °C), assessed through ascending chromatography. Data are expressed as ‘mean ± SD’ ( n = 3–4). No statistically significant difference was observed within the time interval for the radiochemical stability in saline solution ( p = 0.1758) and human serum ( p = 0.8388). ANOVA was conducted, followed by Tukey’s multiple comparisons test.](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_9493/pmc13119493/pmc13119493__pharmaceuticals-19-00594-g003.jpg)
Precursor Fapi, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 10 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/fapi+precursor+(fapi-46/FAPI-46/pmc13119493-107-1-6
Average 94 stars, based on 10 article reviews
Precursor Fapi, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 10 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/fapi+precursor+(fapi-46/FAPI-46/pmc13119493-107-1-6
Average 94 stars, based on 10 article reviews
precursor fapi - by Bioz Stars,
2026-09
94/100 stars
Images
1) Product Images from "Bridging Research and Clinical Practice: Automated [ 68 Ga]Ga-FAPi-46 Synthesis and Quality Control for Oncological PET Imaging"
Article Title: Bridging Research and Clinical Practice: Automated [ 68 Ga]Ga-FAPi-46 Synthesis and Quality Control for Oncological PET Imaging
Journal: Pharmaceuticals
doi: 10.3390/ph19040594
Figure Legend Snippet: Radiochemical stability assessment of [ 68 Ga]Ga-FAPi-46 in ( A ) saline solution (room temperature) and ( B ) human serum (37 °C), assessed through ascending chromatography. Data are expressed as ‘mean ± SD’ ( n = 3–4). No statistically significant difference was observed within the time interval for the radiochemical stability in saline solution ( p = 0.1758) and human serum ( p = 0.8388). ANOVA was conducted, followed by Tukey’s multiple comparisons test.
Techniques Used: Saline, Chromatography
![RP-HPLC chromatographic profiles: ( A ) Free [ 68 Ga]GaCl 3 and the unlabeled FAPi-46 precursor; ( B ) [ 68 Ga]Ga-FAPi-46 evaluated at different time points after radiolabeling (radiochemical stability).](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_9493/pmc13119493/pmc13119493__pharmaceuticals-19-00594-g004.jpg "... ) Free [ 68 Ga]GaCl 3 and the unlabeled FAPi-46 precursor; ( B ) [ 68 Ga]Ga-FAPi-46 ...")
Figure Legend Snippet: RP-HPLC chromatographic profiles: ( A ) Free [ 68 Ga]GaCl 3 and the unlabeled FAPi-46 precursor; ( B ) [ 68 Ga]Ga-FAPi-46 evaluated at different time points after radiolabeling (radiochemical stability).
Techniques Used: Radioactivity
![[ 68 Ga]Ga-FAPi-46 and [ 18 F]FDG PET/CT of a 50-year-old woman with lung adenocarcinoma for initial staging. ( A – G ): [ 68 Ga]Ga-FAPi-46 PET/CT. ( H – N ): [ 18 F]FDG PET/CT. ( A , H ): Maximum intensity projection (anterior view). ( D – G ): [ 68 Ga]Ga-FAPi-46 PET/CT and ( K – N ): [ 18 F]FDG PET/CT axial fusion images. PET/CT shows intense uptake of both ( E ) [ 68 Ga]Ga-FAPi-46 and ( L ) [ 18 F]FDG in the primary tumor in the right lung (green arrows). Tracer uptake is also observed in ipsilateral pulmonary hilum and subcarinal lymph nodes metastases (pink circles and arrows) and in a right supraclavicular lymph node metastasis (yellow arrow). Of note, PET/CT with [ 68 Ga]Ga-FAPi-46 showed greater degree of uptake in mediastinal and supraclavicular lymph nodes ( F , G , D ) in comparison to [ 18 F]FDG ( M , N , K ). A nodular lesion in central nervous system shown on head MRI (( J ), red arrow) is shown on PET/CT with [ 68 Ga]Ga-FAPi-46 (( B , C ), red arrows) but is not identified on [ 18 F]FDG PET/CT ( I ). Thyroid uptake due to thyroiditis (blue arrow) is observed in [ 18 F]FDG PET/CT ( K ) but not in [ 68 Ga]Ga-FAPi-46 images ( D ).](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_9493/pmc13119493/pmc13119493__pharmaceuticals-19-00594-g005.jpg "[ 68 Ga]Ga-FAPi-46 and [ 18 F]FDG PET/CT of a 50-year-old ...")
Figure Legend Snippet: [ 68 Ga]Ga-FAPi-46 and [ 18 F]FDG PET/CT of a 50-year-old woman with lung adenocarcinoma for initial staging. ( A – G ): [ 68 Ga]Ga-FAPi-46 PET/CT. ( H – N ): [ 18 F]FDG PET/CT. ( A , H ): Maximum intensity projection (anterior view). ( D – G ): [ 68 Ga]Ga-FAPi-46 PET/CT and ( K – N ): [ 18 F]FDG PET/CT axial fusion images. PET/CT shows intense uptake of both ( E ) [ 68 Ga]Ga-FAPi-46 and ( L ) [ 18 F]FDG in the primary tumor in the right lung (green arrows). Tracer uptake is also observed in ipsilateral pulmonary hilum and subcarinal lymph nodes metastases (pink circles and arrows) and in a right supraclavicular lymph node metastasis (yellow arrow). Of note, PET/CT with [ 68 Ga]Ga-FAPi-46 showed greater degree of uptake in mediastinal and supraclavicular lymph nodes ( F , G , D ) in comparison to [ 18 F]FDG ( M , N , K ). A nodular lesion in central nervous system shown on head MRI (( J ), red arrow) is shown on PET/CT with [ 68 Ga]Ga-FAPi-46 (( B , C ), red arrows) but is not identified on [ 18 F]FDG PET/CT ( I ). Thyroid uptake due to thyroiditis (blue arrow) is observed in [ 18 F]FDG PET/CT ( K ) but not in [ 68 Ga]Ga-FAPi-46 images ( D ).
Techniques Used: Positron Emission Tomography-Computed Tomography, Comparison
![Schematic representation of the automated synthesis and purification process for [ 68 Ga]Ga-FAPi-46. Adapted from NIAID NIH BioArt Source .](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_9493/pmc13119493/pmc13119493__pharmaceuticals-19-00594-g006.jpg "... automated synthesis and purification process for [ 68 Ga]Ga-FAPi-46. Adapted from NIAID NIH BioArt Source .")
Figure Legend Snippet: Schematic representation of the automated synthesis and purification process for [ 68 Ga]Ga-FAPi-46. Adapted from NIAID NIH BioArt Source .
Techniques Used: Purification
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<scp>
<sup>68</sup>
Ga
</scp>
]
<scp>FAPI</scp>
‐46
<scp>PET</scp>
for assessing fibroinflammatory remodeling in experimental chronic colitis Article Snippet: [68Ga]FAPI-46 was synthesized by adapting previously reported methods with minor modifications.15 Briefly, a 68Ge/68Ga generator (Eckert & Ziegler, Germany) was eluted with 0.1 M HCl through a 0.22 μm GV sterile filter into a sterile collection vial under aseptic conditions. .. The |
