γ-secretase inhibitor dapt solution (Millipore)
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γ Secretase Inhibitor Dapt Solution, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dapt+solution/dapt/pmc10869796-352-3-7
Average 90 stars, based on 1 article reviews
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other:Article Title: Hepcidin expression is associated with increased γ-secretase–mediated cleavage of neogenin in the liver Article Snippet: The inhibitors used in the studies include α-secretase inhibitors, TAPI-1 (#B4686; APE × BIO) and Aderbasib (INCB007839; #HY-10293; MedChemExpress); γ-secretase inhibitors, Article Title: NOTCH1-STAT3 signaling axis regulates astrocytic differentiation of hippocampal neural stem/progenitor cells. Article Snippet: Hippocampal neural stem/progenitor cells (HNPCs) in the hippocampus can differentiate into neurons and astrocytes, and are regulated by complex signaling pathways, such as the NOTCH1–signal transducer and activator of transcription 3 (STAT3) axis, which are crucial for cell fate determination.. However, the exact molecular mechanism underlying HNPC differentiation remains unclear.. This study investigated the role of NOTCH1–STAT3 pathway in HNPC differentiation into neuronal and astrocytic lineages during embryonic development. Incubation:Article Title: WWC1 upregulation accelerates hyperuricemia by reduction in renal uric acid excretion through Hippo signaling pathway. Article Snippet: Received for publication, January 24, 2024, and in revised form, May 24, 2024 Published, Papers in Press, June 19, 2024, https://doi.org/10.1016/j.jbc.2024.107485 Changshun Han, Chengyong He, Xiaoyan Ding, Zixuan Li, Tianyun Peng, Chensong Zhang, Haibing Chen, Zhenghong Zuo, Jiyi Huang*, and Weiping Hu* From the Department of Nephrology, Fujian Clinical Research Center for Chronic Glomerular Disease, The First Affiliated Hospital of Xiamen University, State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China; Department of Endocrinology and Metabolism, Shanghai 10th People’s Hospital, Tongji University, Shanghai, China Staining:Article Title: WWC1 upregulation accelerates hyperuricemia by reduction in renal uric acid excretion through Hippo signaling pathway. Article Snippet: Received for publication, January 24, 2024, and in revised form, May 24, 2024 Published, Papers in Press, June 19, 2024, https://doi.org/10.1016/j.jbc.2024.107485 Changshun Han, Chengyong He, Xiaoyan Ding, Zixuan Li, Tianyun Peng, Chensong Zhang, Haibing Chen, Zhenghong Zuo, Jiyi Huang*, and Weiping Hu* From the Department of Nephrology, Fujian Clinical Research Center for Chronic Glomerular Disease, The First Affiliated Hospital of Xiamen University, State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China; Department of Endocrinology and Metabolism, Shanghai 10th People’s Hospital, Tongji University, Shanghai, China Cell Culture:Article Title: Human endothelial cells promote a human neural stem cell type B phenotype via Notch signaling Article Snippet: Click-iT EdU Alexa Fluor 488 Imaging Kit (Fisher Scientific) instructions were followed and cells on coverslips were incubated with 10 μM EdU for 24 h before fixing. .. 500,000 hNSPCs were cultured in one well of a fibronectin-coated 12-well plate and treated with 10 μM Article Title: PTPσ-mediated PI3P regulation modulates neurodegeneration in C9ORF72-ALS/FTD. Article Snippet: Article PTPs-mediated PI3P regu lation modulates neurodegeneration in C9ORF72-ALS/FTD Article Title: Human endothelial cells promote a human neural stem cell type B phenotype via Notch signaling. Article Snippet: Click-iT EdUAlexa Fluor 488 ImagingKit (Fisher Scientific) instructions were followed and cells on coverslips were incubated with 10μM EdU for 24 h before fixing. .. Negative Control:Article Title: Human endothelial cells promote a human neural stem cell type B phenotype via Notch signaling Article Snippet: Click-iT EdU Alexa Fluor 488 Imaging Kit (Fisher Scientific) instructions were followed and cells on coverslips were incubated with 10 μM EdU for 24 h before fixing. .. 500,000 hNSPCs were cultured in one well of a fibronectin-coated 12-well plate and treated with 10 μM Article Title: Human endothelial cells promote a human neural stem cell type B phenotype via Notch signaling. 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