yap1 phosphorylated on serine 127 (Cell Signaling Technology Inc)
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Yap1 Phosphorylated On Serine 127, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 913 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/yap1/Phospho-YAP+(Ser127)+Antibody/pmc12990376-7-0-6
Average 96 stars, based on 913 article reviews
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1) Product Images from "Promotion of breast cancer by the DNPH1 enzyme"
Article Title: Promotion of breast cancer by the DNPH1 enzyme
Journal: iScience
doi: 10.1016/j.isci.2026.115227
Figure Legend Snippet: Alterations in mammary tumors upon Dnph1 knockout (A) Examples of CD31 staining in mammary tumors from a MMTV-Her2/Dnph1 +/+ and a MMTV-Her2/Dnph1 −/− mouse. Right panels show ImageJ-mediated image modulation to enhance vessel structures, allowing the computer-mediated quantification of blood vessel density. Scale bars, 0.4 mm. (B) Corresponding quantification of vessel density. Tumors were age- and weight-matched; two-tailed, unpaired t test. (C) Tumor vessel density plotted against the weight of the tumor. These tumors were not weight- or age-matched, yet include those shown in panel B. Shown are linear regressions; while the slopes were not significantly different, the Y-intercepts were significantly different ( p = 0.0007). (D) Relative levels of AMP, GMP, and UMP in mammary tumors from MMTV-Her2/Dnph1 +/+ and MMTV-Her2/Dnph1 −/− mice; two-tailed, unpaired t test. (E and F) Immunohistochemical staining for phospho-AMPKα or phospho-YAP1, respectively, on age- and weight-matched tumors as in panel B. Examples of immunohistochemical staining are shown at the bottom. Scale bars, 0.4 mm. Means with standard deviation are shown in panels B and D-F.
Techniques Used: Knock-Out, Staining, Two Tailed Test, Immunohistochemical staining, Standard Deviation
Figure Legend Snippet: Model how DNPH1 promotes breast tumor development and progression This model is centered around a DNPH1-YAP1 axis, yet DNPH1 may utilize to-be-identified effectors other than YAP1 to stimulate, e.g., stem cells or angiogenesis.
Techniques Used:
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