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irradiation with vehicle  (MedChemExpress)


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    MedChemExpress irradiation with vehicle
    Irradiation With Vehicle, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 162 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/vehicle/Ruxolitinib/pmc13368500-140-10-21
    Average 97 stars, based on 162 article reviews
    irradiation with vehicle - by Bioz Stars, 2026-09
    97/100 stars

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    Related Articles

    Injection:

    Article Title: Loss of Kmt2c / d promotes gastric cancer and confers vulnerability to mTORC1 and PD-1 inhibition
    Article Snippet: .. Three days after the first dose of tamoxifen administration, mice were treated with either vehicle (5% ethanol, 5% PEG-400, 5% Tween-80 in PBS, 200 μL per injection) or rapamycin (HY-10219, MedChemExpress, 5 mg/kg, once daily, 5 days a week, 200 μL per injection) via intraperitoneal injection. .. To assess the in vivo responses to rapamycin and ICB, we grafted 5 million TPCD cells into the mammary fat pad of 6- to 8-week-old female mice (C57BL/6J, stock no. 000664, The Jackson Laboratory).

    Article Title: Poorly perfused tumor regions harbor T cells with a glucose-dependent effector phenotype.
    Article Snippet: .. For experiments with the ACSS2i (VY-3-249/HY-104032, MedChemExpress), mice bearing LLC subcutaneous tumors were injected intraperitoneally with 300 μl of ACSS2i (25 mg/kg body weight) prepared in vehicle (10% DMSO, 40% PEG 300, 5% Tween 80, 45% saline) as per manufacturer’s instructions (https://www. medchemexpress.com/Ac-CoA_Synthase_Inhibitor1.html). ..

    Saline:

    Article Title: Poorly perfused tumor regions harbor T cells with a glucose-dependent effector phenotype.
    Article Snippet: .. For experiments with the ACSS2i (VY-3-249/HY-104032, MedChemExpress), mice bearing LLC subcutaneous tumors were injected intraperitoneally with 300 μl of ACSS2i (25 mg/kg body weight) prepared in vehicle (10% DMSO, 40% PEG 300, 5% Tween 80, 45% saline) as per manufacturer’s instructions (https://www. medchemexpress.com/Ac-CoA_Synthase_Inhibitor1.html). ..

    Article Title: Increased glucose availability sensitizes pancreatic cancer to macrophage-targeting immunotherapies
    Article Snippet: .. Treatments included vehicle (10% PEG-400, 4% Tween-80, and 86% saline), pexidartinib/PLX3397 (50 mg/kg, daily, oral gavage; MedChemExpress, HY-16749), or PF-4136309 (10 mg/kg, twice daily, oral gavage, MedChemExpress, HY-13245) (16,22,23). ..

    Article Title: Hypoxic CA9-high mesenchymal-like glioma stem cells promote ANXA1-FPR1-dependent macrophage polarization in recurrent glioblastoma.
    Article Snippet: .. CsH (10 mg/kg; MedChemExpress, HY-100183) dissolved in vehicle (10% DMSO, 40% PEG300, 5% Tween 80, 45% saline) or vehicle alone was administered intraperitoneally every other day beginning on day 3 after implantation. ..

    Cell Culture:

    Article Title: Effects of Lycium barbarum polysaccharide on the activation of pathogenic CD4 + T cells in a mouse model of multiple sclerosis
    Article Snippet: Th17 polarization was induced using IL-6 (20 ng/mL, R&D Systems), IL-1β (10 ng/mL, R&D Systems), IL-23 (20 ng/mL, R&D Systems), anti-interferon-γ (IFN-γ; 5 μg/mL, R&D Systems), and anti-IL-4 antibody (5 μg/mL). .. Cells were cultured for 3–5 days with vehicle (dimethyl sulfoxide) or the AP-1 inhibitor T-5224 (10 μM dissolved in dimethyl sulfoxide; MCE, Shanghai, China) before being stimulated with phorbol 12-myristate 13-acetate (PMA; 1 mg/mL, MCE), ionomycin (500 μg/mL, MCE), and brefeldin A (5 μg/mL, MCE) for 3–4 hours to enhance cytokine production. ..



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    <t>Compound-level</t> activity across feature spaces. The heatmap shows compound-level activity significance for CellPaintSSL, OpenPhenom, and uniDINO. In this scenario, compound-treated well profiles served as queries, replicate wells of the same compound were considered positives, and dimethyl sulfoxide <t>(DMSO)</t> wells were considered negatives. Color represents −log10 of the adjusted p -value, while gray cells indicate non-significant compound–feature-space pairs. Compounds are ordered by their activity classification pattern across feature spaces: shared3 denotes compounds significant in all three feature spaces, shared2 denotes compounds significant in exactly two feature spaces, unique denotes compounds significant in only one feature space, and inactive denotes compounds not classified as activity-positive in any feature space. Within each block, compounds are ordered by the summed −log10 adjusted p -value across the three feature spaces, from higher to lower values.
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    Image Search Results


    Compound-level activity across feature spaces. The heatmap shows compound-level activity significance for CellPaintSSL, OpenPhenom, and uniDINO. In this scenario, compound-treated well profiles served as queries, replicate wells of the same compound were considered positives, and dimethyl sulfoxide (DMSO) wells were considered negatives. Color represents −log10 of the adjusted p -value, while gray cells indicate non-significant compound–feature-space pairs. Compounds are ordered by their activity classification pattern across feature spaces: shared3 denotes compounds significant in all three feature spaces, shared2 denotes compounds significant in exactly two feature spaces, unique denotes compounds significant in only one feature space, and inactive denotes compounds not classified as activity-positive in any feature space. Within each block, compounds are ordered by the summed −log10 adjusted p -value across the three feature spaces, from higher to lower values.

    Journal: International Journal of Molecular Sciences

    Article Title: Retrieval-Based Evaluation of Cell Painting Feature Spaces Reveals Differences in the Preservation of Biologically Meaningful Phenotypic Similarity

    doi: 10.3390/ijms27135727

    Figure Lengend Snippet: Compound-level activity across feature spaces. The heatmap shows compound-level activity significance for CellPaintSSL, OpenPhenom, and uniDINO. In this scenario, compound-treated well profiles served as queries, replicate wells of the same compound were considered positives, and dimethyl sulfoxide (DMSO) wells were considered negatives. Color represents −log10 of the adjusted p -value, while gray cells indicate non-significant compound–feature-space pairs. Compounds are ordered by their activity classification pattern across feature spaces: shared3 denotes compounds significant in all three feature spaces, shared2 denotes compounds significant in exactly two feature spaces, unique denotes compounds significant in only one feature space, and inactive denotes compounds not classified as activity-positive in any feature space. Within each block, compounds are ordered by the summed −log10 adjusted p -value across the three feature spaces, from higher to lower values.

    Article Snippet: After 24 h, 10 μL of either DMSO vehicle (MedChemExpress, Shanghai, China) or compound solution was added to each well.

    Techniques: Activity Assay, Blocking Assay