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vegfa121  (ProSpec)

 
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    ProSpec vegfa121
    Vegfa121, supplied by ProSpec, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/vegfa121/product/ProSpec
    Average 90 stars, based on 1 article reviews
    vegfa121 - by Bioz Stars, 2026-03
    90/100 stars

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    Image Search Results


    NGR2 increased hypoxia in the colon mucosa with an increased ratio of serum VEGFA165/VEGFA121 and increased protein expression of Rap1GAP and TSP1. (A) The protein expression levels of VEGFR2, VEGFR2 (p1175), VEGFR2 (p1214), Rap1GAP, TSP1, and HIF-1α in the colon mucosa; (B,C) the serum contents of VEGFA165 and VEGFA121 and the ratio of VEGFA165/VEGFA121; (D,E) the concentration of intracellular pyruvate and lactic acid in the colonic mucosa. The data are means ± SEM of 3 independent experiments performed in triplicate. One-way ANOVA and Student’s t-test (**, P<0.001 vs. control).

    Journal: Annals of Translational Medicine

    Article Title: Notoginsenoside R2 induces colonic microvascular injuries via regulating the Rap1GAP/PI3K/Akt signaling pathway

    doi: 10.21037/atm-21-5898

    Figure Lengend Snippet: NGR2 increased hypoxia in the colon mucosa with an increased ratio of serum VEGFA165/VEGFA121 and increased protein expression of Rap1GAP and TSP1. (A) The protein expression levels of VEGFR2, VEGFR2 (p1175), VEGFR2 (p1214), Rap1GAP, TSP1, and HIF-1α in the colon mucosa; (B,C) the serum contents of VEGFA165 and VEGFA121 and the ratio of VEGFA165/VEGFA121; (D,E) the concentration of intracellular pyruvate and lactic acid in the colonic mucosa. The data are means ± SEM of 3 independent experiments performed in triplicate. One-way ANOVA and Student’s t-test (**, P<0.001 vs. control).

    Article Snippet: VEGFA121 (no: SEB851Ra) and VEGFA (no: SEA143Ra) ELISA kits were purchased from Cloud-Clone Co. Anti-VEGFR2 antibody (ab11939), anti-VEGFR2 (phospho Y1214) antibody (ab5475), and anti-Rap1GAP antibody (ab32373) were purchased from Abcam Co. (London, United Kingdom).

    Techniques: Expressing, Concentration Assay, Control

    Panax notoginseng reversed the disordered ratio of VEGFA165/VEGFA121 and adjusted the imbalance of pro-inflammatory and anti-inflammatory cytokines. A-C: Increased serum concentrations of VEGF165 and VEGF121, as well as the increased ratio of VEGF165/VEGF121 in the experimental colitis groups were down-regulated by medium and high doses of PN; D-F: The increased serum concentrations of IL-6 and TNF-α and decreased serum concentrations of IL-4 and IL-10 in the experimental colitis groups were reversed by PN in a dose-dependent manner. Results are expressed as mean ± SD of three independent experiments performed in triplicate. a P < 0.05, b P < 0.01 vs normal control. IL: Interleukin; PN: Panax notoginseng ; TNF: Tumor necrosis factor; VEGF: Vascular endothelial growth factor.

    Journal: World Journal of Gastroenterology

    Article Title: Effects of initiating time and dosage of Panax notoginseng on mucosal microvascular injury in experimental colitis

    doi: 10.3748/wjg.v23.i47.8308

    Figure Lengend Snippet: Panax notoginseng reversed the disordered ratio of VEGFA165/VEGFA121 and adjusted the imbalance of pro-inflammatory and anti-inflammatory cytokines. A-C: Increased serum concentrations of VEGF165 and VEGF121, as well as the increased ratio of VEGF165/VEGF121 in the experimental colitis groups were down-regulated by medium and high doses of PN; D-F: The increased serum concentrations of IL-6 and TNF-α and decreased serum concentrations of IL-4 and IL-10 in the experimental colitis groups were reversed by PN in a dose-dependent manner. Results are expressed as mean ± SD of three independent experiments performed in triplicate. a P < 0.05, b P < 0.01 vs normal control. IL: Interleukin; PN: Panax notoginseng ; TNF: Tumor necrosis factor; VEGF: Vascular endothelial growth factor.

    Article Snippet: ELISA kits for vascular endothelial growth factor (VEGF)A165 and VEGFA121 were purchased from Cloud-Clone Corp. (Katy, TX, United States).

    Techniques:

    Panax notoginseng reversed the disordered ratio of VEGFA165/VEGFA121 and adjusted the imbalance of pro-inflammatory and anti-inflammatory cytokines. A-C: Increased serum concentrations of VEGF165 and VEGF121, as well as the increased ratio of VEGF165/VEGF121 in the experimental colitis groups were down-regulated by medium and high doses of PN; D-F: The increased serum concentrations of IL-6 and TNF-α and decreased serum concentrations of IL-4 and IL-10 in the experimental colitis groups were reversed by PN in a dose-dependent manner. Results are expressed as mean ± SD of three independent experiments performed in triplicate. a P < 0.05, b P < 0.01 vs normal control. IL: Interleukin; PN: Panax notoginseng ; TNF: Tumor necrosis factor; VEGF: Vascular endothelial growth factor.

    Journal: World Journal of Gastroenterology

    Article Title: Effects of initiating time and dosage of Panax notoginseng on mucosal microvascular injury in experimental colitis

    doi: 10.3748/wjg.v23.i47.8308

    Figure Lengend Snippet: Panax notoginseng reversed the disordered ratio of VEGFA165/VEGFA121 and adjusted the imbalance of pro-inflammatory and anti-inflammatory cytokines. A-C: Increased serum concentrations of VEGF165 and VEGF121, as well as the increased ratio of VEGF165/VEGF121 in the experimental colitis groups were down-regulated by medium and high doses of PN; D-F: The increased serum concentrations of IL-6 and TNF-α and decreased serum concentrations of IL-4 and IL-10 in the experimental colitis groups were reversed by PN in a dose-dependent manner. Results are expressed as mean ± SD of three independent experiments performed in triplicate. a P < 0.05, b P < 0.01 vs normal control. IL: Interleukin; PN: Panax notoginseng ; TNF: Tumor necrosis factor; VEGF: Vascular endothelial growth factor.

    Article Snippet: The serum concentrations of VEGFA165 (Cloud-Clone Corp.), VEGFA121 (Cloud-Clone Corp.), IL-4 (R&D Systems), IL-6 (R&D Systems), IL-10 (R&D Systems) and TNF-α (R&D Systems) were detected using the appropriate ELISA kits.

    Techniques: