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uacc 3133  (ATCC)


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    Structured Review

    ATCC uacc 3133
    ILC lines CAMA1-luc, <t>UACC-3133-luc,</t> and ZR-75-30-luc were challenged via MIND into mice (n=5/cell line) supplemented with 30µM E2 in the drinking water. A) Whole body luminescence measured over the course of the experiment. Darker lines represent group averages until euthanasia of first mouse per group. Faded lines represent individual mice until their individual time of euthanasia. B) Representative images of mice at 1 week and 23 weeks after tumor challenge. Multiple UACC-3133-luc mice (n=3) succumbed to rapid metastatic progression leading to incomplete ex vivo BLI metastasis data. C) Total metastatic burden as measured by ex vivo BLI. One-way lognormal ANOVA: *adj.p<0.05; **, ANOVA adj.p<0.01. D) Metastatic burden per organ, as measured by ex vivo BLI. One-way lognormal ANOVA: *, ANOVA adj.p<0.05; **, ANOVA adj.p<0.01; ***, ANOVA adj.p<0.001; ****, ANOVA adj.p<0.0001.
    Uacc 3133, supplied by ATCC, used in various techniques. Bioz Stars score: 92/100, based on 12 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Images

    1) Product Images from "Advanced models of lobular breast cancer metastasis capture clinical organ tropism, endocrine response, and bone remodeling"

    Article Title: Advanced models of lobular breast cancer metastasis capture clinical organ tropism, endocrine response, and bone remodeling

    Journal: bioRxiv

    doi: 10.64898/2026.03.13.711653

    ILC lines CAMA1-luc, UACC-3133-luc, and ZR-75-30-luc were challenged via MIND into mice (n=5/cell line) supplemented with 30µM E2 in the drinking water. A) Whole body luminescence measured over the course of the experiment. Darker lines represent group averages until euthanasia of first mouse per group. Faded lines represent individual mice until their individual time of euthanasia. B) Representative images of mice at 1 week and 23 weeks after tumor challenge. Multiple UACC-3133-luc mice (n=3) succumbed to rapid metastatic progression leading to incomplete ex vivo BLI metastasis data. C) Total metastatic burden as measured by ex vivo BLI. One-way lognormal ANOVA: *adj.p<0.05; **, ANOVA adj.p<0.01. D) Metastatic burden per organ, as measured by ex vivo BLI. One-way lognormal ANOVA: *, ANOVA adj.p<0.05; **, ANOVA adj.p<0.01; ***, ANOVA adj.p<0.001; ****, ANOVA adj.p<0.0001.
    Figure Legend Snippet: ILC lines CAMA1-luc, UACC-3133-luc, and ZR-75-30-luc were challenged via MIND into mice (n=5/cell line) supplemented with 30µM E2 in the drinking water. A) Whole body luminescence measured over the course of the experiment. Darker lines represent group averages until euthanasia of first mouse per group. Faded lines represent individual mice until their individual time of euthanasia. B) Representative images of mice at 1 week and 23 weeks after tumor challenge. Multiple UACC-3133-luc mice (n=3) succumbed to rapid metastatic progression leading to incomplete ex vivo BLI metastasis data. C) Total metastatic burden as measured by ex vivo BLI. One-way lognormal ANOVA: *adj.p<0.05; **, ANOVA adj.p<0.01. D) Metastatic burden per organ, as measured by ex vivo BLI. One-way lognormal ANOVA: *, ANOVA adj.p<0.05; **, ANOVA adj.p<0.01; ***, ANOVA adj.p<0.001; ****, ANOVA adj.p<0.0001.

    Techniques Used: Ex Vivo



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    ILC lines CAMA1-luc, <t>UACC-3133-luc,</t> and ZR-75-30-luc were challenged via MIND into mice (n=5/cell line) supplemented with 30µM E2 in the drinking water. A) Whole body luminescence measured over the course of the experiment. Darker lines represent group averages until euthanasia of first mouse per group. Faded lines represent individual mice until their individual time of euthanasia. B) Representative images of mice at 1 week and 23 weeks after tumor challenge. Multiple UACC-3133-luc mice (n=3) succumbed to rapid metastatic progression leading to incomplete ex vivo BLI metastasis data. C) Total metastatic burden as measured by ex vivo BLI. One-way lognormal ANOVA: *adj.p<0.05; **, ANOVA adj.p<0.01. D) Metastatic burden per organ, as measured by ex vivo BLI. One-way lognormal ANOVA: *, ANOVA adj.p<0.05; **, ANOVA adj.p<0.01; ***, ANOVA adj.p<0.001; ****, ANOVA adj.p<0.0001.
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    ILC lines CAMA1-luc, <t>UACC-3133-luc,</t> and ZR-75-30-luc were challenged via MIND into mice (n=5/cell line) supplemented with 30µM E2 in the drinking water. A) Whole body luminescence measured over the course of the experiment. Darker lines represent group averages until euthanasia of first mouse per group. Faded lines represent individual mice until their individual time of euthanasia. B) Representative images of mice at 1 week and 23 weeks after tumor challenge. Multiple UACC-3133-luc mice (n=3) succumbed to rapid metastatic progression leading to incomplete ex vivo BLI metastasis data. C) Total metastatic burden as measured by ex vivo BLI. One-way lognormal ANOVA: *adj.p<0.05; **, ANOVA adj.p<0.01. D) Metastatic burden per organ, as measured by ex vivo BLI. One-way lognormal ANOVA: *, ANOVA adj.p<0.05; **, ANOVA adj.p<0.01; ***, ANOVA adj.p<0.001; ****, ANOVA adj.p<0.0001.
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    Image Search Results


    ILC lines CAMA1-luc, UACC-3133-luc, and ZR-75-30-luc were challenged via MIND into mice (n=5/cell line) supplemented with 30µM E2 in the drinking water. A) Whole body luminescence measured over the course of the experiment. Darker lines represent group averages until euthanasia of first mouse per group. Faded lines represent individual mice until their individual time of euthanasia. B) Representative images of mice at 1 week and 23 weeks after tumor challenge. Multiple UACC-3133-luc mice (n=3) succumbed to rapid metastatic progression leading to incomplete ex vivo BLI metastasis data. C) Total metastatic burden as measured by ex vivo BLI. One-way lognormal ANOVA: *adj.p<0.05; **, ANOVA adj.p<0.01. D) Metastatic burden per organ, as measured by ex vivo BLI. One-way lognormal ANOVA: *, ANOVA adj.p<0.05; **, ANOVA adj.p<0.01; ***, ANOVA adj.p<0.001; ****, ANOVA adj.p<0.0001.

    Journal: bioRxiv

    Article Title: Advanced models of lobular breast cancer metastasis capture clinical organ tropism, endocrine response, and bone remodeling

    doi: 10.64898/2026.03.13.711653

    Figure Lengend Snippet: ILC lines CAMA1-luc, UACC-3133-luc, and ZR-75-30-luc were challenged via MIND into mice (n=5/cell line) supplemented with 30µM E2 in the drinking water. A) Whole body luminescence measured over the course of the experiment. Darker lines represent group averages until euthanasia of first mouse per group. Faded lines represent individual mice until their individual time of euthanasia. B) Representative images of mice at 1 week and 23 weeks after tumor challenge. Multiple UACC-3133-luc mice (n=3) succumbed to rapid metastatic progression leading to incomplete ex vivo BLI metastasis data. C) Total metastatic burden as measured by ex vivo BLI. One-way lognormal ANOVA: *adj.p<0.05; **, ANOVA adj.p<0.01. D) Metastatic burden per organ, as measured by ex vivo BLI. One-way lognormal ANOVA: *, ANOVA adj.p<0.05; **, ANOVA adj.p<0.01; ***, ANOVA adj.p<0.001; ****, ANOVA adj.p<0.0001.

    Article Snippet: CAMA-1 (ATCC HTB-21), UACC-3133 (CRL-2988), and ZR-75-30 (CRL-1504) were maintained as described [ ].

    Techniques: Ex Vivo

    ( A ). Cell viability of cells treated with curcumin for 24 h. Viability was determined by the resazurin assay. Data were averaged from three independent experiments with six replicas each, and the standard deviation is shown. ( B) . VEGF concentrations in cell culture supernatant upon 24 h exposure to IL-1β, curcumin, and combinations of both were determined by ELISA for ( B ) MCF-7, ( C ) SK-BR-3, ( D ) MDA-MB-231, and ( E ) UACC-3199. Data are averaged from three independent experiments with two replicas each, and median and quartiles are shown. ( F) . Effects of inhibition of MAP-kinases on curcumin-induced VEGF secretion in MCF-7. SB: SB203580 (p38-MAPK-inhibitor); UO: UO126 (ERK-inhibitor). Data are expressed relative to solvent-treated cells. Data averaged from three independent experiments with three replicas each, and the standard error is shown. * p < 0.05, n.s.: not significant (ANOVA).

    Journal: Oncology Research

    Article Title: Interplay of Interleukin-1 β and Curcumin on VEGF Expression in Breast Cancer Cells

    doi: 10.32604/or.2025.072793

    Figure Lengend Snippet: ( A ). Cell viability of cells treated with curcumin for 24 h. Viability was determined by the resazurin assay. Data were averaged from three independent experiments with six replicas each, and the standard deviation is shown. ( B) . VEGF concentrations in cell culture supernatant upon 24 h exposure to IL-1β, curcumin, and combinations of both were determined by ELISA for ( B ) MCF-7, ( C ) SK-BR-3, ( D ) MDA-MB-231, and ( E ) UACC-3199. Data are averaged from three independent experiments with two replicas each, and median and quartiles are shown. ( F) . Effects of inhibition of MAP-kinases on curcumin-induced VEGF secretion in MCF-7. SB: SB203580 (p38-MAPK-inhibitor); UO: UO126 (ERK-inhibitor). Data are expressed relative to solvent-treated cells. Data averaged from three independent experiments with three replicas each, and the standard error is shown. * p < 0.05, n.s.: not significant (ANOVA).

    Article Snippet: All cell lines MCF-7 (ATCC-HTB-22), SK-BR-3 (ATCC-HTB-30), MDA-MB-231 (ATCC-HTB-26), and UACC-3199 (ATCC-CRL-2983) were obtained from the American Type Culture Collection (ATCC, via LGC Standards, Wesel, Germany).

    Techniques: Resazurin Assay, Standard Deviation, Cell Culture, Enzyme-linked Immunosorbent Assay, Inhibition, Solvent