drug ttp22 tocris tocris (Tocris)
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drug ttp22 tocris tocris
Drug Ttp22 Tocris Tocris, supplied by Tocris, used in various techniques. Bioz Stars score: 92/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ttp22/TTP+22/10__7554_slash_elife__65811-141-19-21
Average 92 stars, based on 5 article reviews
Drug Ttp22 Tocris Tocris, supplied by Tocris, used in various techniques. Bioz Stars score: 92/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ttp22/TTP+22/10__7554_slash_elife__65811-141-19-21
Average 92 stars, based on 5 article reviews
drug ttp22 tocris tocris - by Bioz Stars,
2026-11
92/100 stars
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1) Product Images from "Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures"
Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures
Journal: eLife
doi: 10.7554/elife.65811
Figure Legend Snippet: Figure 4. Compounds promoting AT1 cell differentiation lead to concomitant loss of AT2 marker gene expression and WNT-dependent transcription. (A) IC261, CX-4945, and DMAT treatments (48 h) lead to downregulation of AT2 cell markers. TTP22 and Emodin (also CK2 inhibitors) do not lead to the same phenotype, possibly due to differences in potency/target affinity. Expression levels relative to DMSO control. Three biological replicates (consisting of 2 technical replicates each) were analyzed per compound. (B) Casein Kinase inhibition by IC261, CX-4945, and DMAT (6 h) leads to reduced Axin2 relative expression. Treatment with TTP22 or Emodin does not significantly affect Axin2 levels. More than three biological replicates were analyzed. (C) CK inhibition reduced WNT/β-catenin-dependent transcription in HEK293T epithelial cells (SuperTOPFlash-based luciferase assay). (B) Mean values are displayed; error bars represent S.D.; p-values from one-way ANOVA, Tukey’s multiple comparisons test. (C) Mean values displayed; error bars represent S.D.; p-values from one-way ANOVA, Tukey’s multiple comparisons test; displayed p-values refer to comparisons with WNT3A- treated condition.
Techniques Used: Cell Differentiation, Marker, Gene Expression, Expressing, Control, Inhibition, Luciferase
Related Articles
Expressing:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Control:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Inhibition:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Luciferase:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Recombinant:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Transfection:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Construct:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Plasmid Preparation:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Mutagenesis:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Reporter Assay:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Reverse Transcription:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. SYBR Green Assay:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Sequencing:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Software:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Western Blot:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Membrane:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Isolation:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Incubation:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Comparison:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Derivative Assay:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. Cell Culture:Article Title: Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures Article Snippet: Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).Chemical compound, drug , Emodin , Tocris , Tocris:3811 , (10 µM).. Chemical compound, drug , TTP22 , Tocris , Tocris:4432 , (10 µM).. Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM).Chemical compound, drug , IC261 , Sigma , Sigma:I0658 , (10 µM). Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells. Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following Henslee et al., 2017) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and Article Title: Casein Kinase 1 Underlies Temperature Compensation of Circadian Rhythms in Human Red Blood Cells Article Snippet: Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.Concentrations of the drug that did not result in hemolysis or altered viability or morphology under our experimental conditions (following ) were chosen for subsequent time-course experiments.. The drugs used in this study—staurosporine, PF-670462, D4476 (all Sigma-Aldrich), and TTP22 (Tocris Biosciences; Bristol, UK)—were prepared in DMSO according to the manufacturer’s instructions.. Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration.Drugs were diluted in KHB and delivered as a 10X concentration bolus to RBC suspensions to achieve the final concentration. |
