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terazosin  (MedChemExpress)


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    Structured Review

    MedChemExpress terazosin
    Terazosin, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/terazosin/Terazosin/pm42266013-47-46-50
    Average 94 stars, based on 7 article reviews
    terazosin - by Bioz Stars, 2026-09
    94/100 stars

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    Related Articles

    Control:

    Article Title: Terazosin Attenuates Neuronal Pyroptosis by Regulating the Mitochondrial ROS / NLRP3 Inflammasome Axis Through Mitophagy in Cerebral Ischemia–Reperfusion Injury
    Article Snippet: .. After successful model establishment, mice were randomly divided into the following groups ( n = 18 per group): Sham group: mice underwent sham surgery without filament insertion; MCAO/R group: mice subjected to middle cerebral artery occlusion/reperfusion (MCAO/R) modeling; MCAO/ R + TZ group: mice received intraperitoneal injections of terazosin (TZ; HY‐B0371, MedChemExpress, Monmouth Junction, NJ, USA) at doses of 0.1, 1, 10, or 100 μg/kg 30 min before occlusion [ ]; MCAO/ R + TZ + PE group: mice received intraperitoneal injections of 10 μg/kg TZ and 5 mg/kg phenylephrine (PE, an α1‐AR agonist; Sigma) at the onset of reperfusion [ ]; MCAO/ R + TZ + M group: mice received intraperitoneal injections of 10 μg/kg TZ and 3 mg/kg Mdivi‐1 (a mitophagy inhibitor; HY‐15886, MCE) at the onset of reperfusion [ ]; MCAO/ R + TZ + V1 group: mice were administered 10 μg/kg TZ together with the corresponding vehicle for Mdivi‐1 (10% dimethyl sulfoxide [DMSO] + 90% corn oil); MCAO/ R + TZ + N group: mice received intraperitoneal injections of 10 μg/kg TZ and 4 mg/kg Nigericin (an NLRP3 activator; HY‐160638, MCE) immediately after MCAO surgery [ ]; MCAO/ R + TZ + V2 group: mice were administered 10 μg/kg TZ together with the vehicle control for nigericin (10% ethanol + 90% corn oil). ..

    Cell Culture:

    Article Title: Mitochondria ATP Pro‐Ferroptosis by Adjusting the Conversion of PUFA to PUFA‐PLs
    Article Snippet: .. The reagents used are Ferrostain‐1 (S7243, Selleck), DFO (Y0001937, Sigma), Propidium iodide (P4170, Sigma), BODIPY581/591 C11 (D3861, ThermoFisher), DCFH‐DA (35845, Sigma), Cystine (1161586, Sigma), Methionine (M0960000, Sigma), Glutamine (1294808, Sigma), αKG (349631, Sigma), Pyruvate (P2256, MCE), Devimistat (HY‐15453, MCE), Terazosin (HY‐B0371, MCE), oligomycin (HY‐N6782, MCE), FCCP (HY‐100410, MCE), rotenone (557368, Sigma), antimycin A FIGURE 6 | Glutamine deprivation can inhibit the uptake of fatty acids. (A–E) MEFs cells were cultured in the medium without cystine and ± glutamine as indicated for 10 h. The metabolites levels were measured by ultrahigh performance liquid chromatography‐high resolution mass spectrometry (UHPLC‐HRMS). (F) H1299 cells were cultured ± cystine, or ± glutamine as indicated for 10 h, the cell by BODIPY C16 staining coupled with flow cytometry. (G) Schematic of glutamine regulating ferroptosis by modulating mitochondrial ATP production (It was created using BioGDP, https://biogdp.com/). ..

    Article Title: Terazosin, a repurposed GPR119 agonist, ameliorates mitophagy and β-cell function in NAFPD by inhibiting MST1-Foxo3a signalling pathway.
    Article Snippet: .. The MIN6 mouse pancreatic β-cell line was cultured in high-glucose DMEM medium with 10% fetal bovine serum (FBS, Gibco, Carlsbad, CA) under a humidified environment at 5% CO2 and 37 C. MIN6 cells were treated with terazosin (20 μmol/L, MCE, HY-B0371A) and a set of screened drugs (ZINC-1872 10 μmol/L, ZINC-6192 5 μmol/L, ZINC-3652 1 μmol/L, ZINC-6601 10 μmol/L, ZINC-4414 1 μmol/L, ZINC-2427 20 μmol/L, ZINC-6792 5 μmol/L) for 24 h individually. .. MBX-2982 (10 μmol/L, MCE, HY-15291) served as a positive control.

    Chromatography:

    Article Title: Mitochondria ATP Pro‐Ferroptosis by Adjusting the Conversion of PUFA to PUFA‐PLs
    Article Snippet: .. The reagents used are Ferrostain‐1 (S7243, Selleck), DFO (Y0001937, Sigma), Propidium iodide (P4170, Sigma), BODIPY581/591 C11 (D3861, ThermoFisher), DCFH‐DA (35845, Sigma), Cystine (1161586, Sigma), Methionine (M0960000, Sigma), Glutamine (1294808, Sigma), αKG (349631, Sigma), Pyruvate (P2256, MCE), Devimistat (HY‐15453, MCE), Terazosin (HY‐B0371, MCE), oligomycin (HY‐N6782, MCE), FCCP (HY‐100410, MCE), rotenone (557368, Sigma), antimycin A FIGURE 6 | Glutamine deprivation can inhibit the uptake of fatty acids. (A–E) MEFs cells were cultured in the medium without cystine and ± glutamine as indicated for 10 h. The metabolites levels were measured by ultrahigh performance liquid chromatography‐high resolution mass spectrometry (UHPLC‐HRMS). (F) H1299 cells were cultured ± cystine, or ± glutamine as indicated for 10 h, the cell by BODIPY C16 staining coupled with flow cytometry. (G) Schematic of glutamine regulating ferroptosis by modulating mitochondrial ATP production (It was created using BioGDP, https://biogdp.com/). ..

    Mass Spectrometry:

    Article Title: Mitochondria ATP Pro‐Ferroptosis by Adjusting the Conversion of PUFA to PUFA‐PLs
    Article Snippet: .. The reagents used are Ferrostain‐1 (S7243, Selleck), DFO (Y0001937, Sigma), Propidium iodide (P4170, Sigma), BODIPY581/591 C11 (D3861, ThermoFisher), DCFH‐DA (35845, Sigma), Cystine (1161586, Sigma), Methionine (M0960000, Sigma), Glutamine (1294808, Sigma), αKG (349631, Sigma), Pyruvate (P2256, MCE), Devimistat (HY‐15453, MCE), Terazosin (HY‐B0371, MCE), oligomycin (HY‐N6782, MCE), FCCP (HY‐100410, MCE), rotenone (557368, Sigma), antimycin A FIGURE 6 | Glutamine deprivation can inhibit the uptake of fatty acids. (A–E) MEFs cells were cultured in the medium without cystine and ± glutamine as indicated for 10 h. The metabolites levels were measured by ultrahigh performance liquid chromatography‐high resolution mass spectrometry (UHPLC‐HRMS). (F) H1299 cells were cultured ± cystine, or ± glutamine as indicated for 10 h, the cell by BODIPY C16 staining coupled with flow cytometry. (G) Schematic of glutamine regulating ferroptosis by modulating mitochondrial ATP production (It was created using BioGDP, https://biogdp.com/). ..

    Staining:

    Article Title: Mitochondria ATP Pro‐Ferroptosis by Adjusting the Conversion of PUFA to PUFA‐PLs
    Article Snippet: .. The reagents used are Ferrostain‐1 (S7243, Selleck), DFO (Y0001937, Sigma), Propidium iodide (P4170, Sigma), BODIPY581/591 C11 (D3861, ThermoFisher), DCFH‐DA (35845, Sigma), Cystine (1161586, Sigma), Methionine (M0960000, Sigma), Glutamine (1294808, Sigma), αKG (349631, Sigma), Pyruvate (P2256, MCE), Devimistat (HY‐15453, MCE), Terazosin (HY‐B0371, MCE), oligomycin (HY‐N6782, MCE), FCCP (HY‐100410, MCE), rotenone (557368, Sigma), antimycin A FIGURE 6 | Glutamine deprivation can inhibit the uptake of fatty acids. (A–E) MEFs cells were cultured in the medium without cystine and ± glutamine as indicated for 10 h. The metabolites levels were measured by ultrahigh performance liquid chromatography‐high resolution mass spectrometry (UHPLC‐HRMS). (F) H1299 cells were cultured ± cystine, or ± glutamine as indicated for 10 h, the cell by BODIPY C16 staining coupled with flow cytometry. (G) Schematic of glutamine regulating ferroptosis by modulating mitochondrial ATP production (It was created using BioGDP, https://biogdp.com/). ..

    Flow Cytometry:

    Article Title: Mitochondria ATP Pro‐Ferroptosis by Adjusting the Conversion of PUFA to PUFA‐PLs
    Article Snippet: .. The reagents used are Ferrostain‐1 (S7243, Selleck), DFO (Y0001937, Sigma), Propidium iodide (P4170, Sigma), BODIPY581/591 C11 (D3861, ThermoFisher), DCFH‐DA (35845, Sigma), Cystine (1161586, Sigma), Methionine (M0960000, Sigma), Glutamine (1294808, Sigma), αKG (349631, Sigma), Pyruvate (P2256, MCE), Devimistat (HY‐15453, MCE), Terazosin (HY‐B0371, MCE), oligomycin (HY‐N6782, MCE), FCCP (HY‐100410, MCE), rotenone (557368, Sigma), antimycin A FIGURE 6 | Glutamine deprivation can inhibit the uptake of fatty acids. (A–E) MEFs cells were cultured in the medium without cystine and ± glutamine as indicated for 10 h. The metabolites levels were measured by ultrahigh performance liquid chromatography‐high resolution mass spectrometry (UHPLC‐HRMS). (F) H1299 cells were cultured ± cystine, or ± glutamine as indicated for 10 h, the cell by BODIPY C16 staining coupled with flow cytometry. (G) Schematic of glutamine regulating ferroptosis by modulating mitochondrial ATP production (It was created using BioGDP, https://biogdp.com/). ..



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    Effects of terazosin and leuprolide acetate treatments on molecular and biochemical parameters in endometriotic tissue. Bar graphs illustrate the tissue concentrations of ( A ) Steroidogenic Factor-1 (SF-1), ( B ) Interleukin-8 (IL-8), ( C ) Interleukin-6 (IL-6), ( D ) Vascular Endothelial Growth Factor (VEGF), ( E ) Tumor Necrosis Factor-alpha (TNF-α), ( F ) Hypoxia-Inducible Factor-1 Alpha (HIF-1A), ( G ) Total Antioxidant Status (TAS), ( H ) Total Oxidant Status (TOS), ( I ) Oxidative Stress Index (OSI), ( J ) Nuclear Factor kappa-B (NF-κB), and ( K ) Prostaglandin E2 (PGE2). S: Sham group; E: Endometriosis control group.

    Journal: International Journal of Molecular Sciences

    Article Title: Terazosin as a Non-Hormonal Treatment for Endometriosis

    doi: 10.3390/ijms27094093

    Figure Lengend Snippet: Effects of terazosin and leuprolide acetate treatments on molecular and biochemical parameters in endometriotic tissue. Bar graphs illustrate the tissue concentrations of ( A ) Steroidogenic Factor-1 (SF-1), ( B ) Interleukin-8 (IL-8), ( C ) Interleukin-6 (IL-6), ( D ) Vascular Endothelial Growth Factor (VEGF), ( E ) Tumor Necrosis Factor-alpha (TNF-α), ( F ) Hypoxia-Inducible Factor-1 Alpha (HIF-1A), ( G ) Total Antioxidant Status (TAS), ( H ) Total Oxidant Status (TOS), ( I ) Oxidative Stress Index (OSI), ( J ) Nuclear Factor kappa-B (NF-κB), and ( K ) Prostaglandin E2 (PGE2). S: Sham group; E: Endometriosis control group.

    Article Snippet: Group E + T (Terazosin): Oral gavage with terazosin by dissolving the tablets in sterile saline at a daily dose of 5 mg/kg (Hytrin ® , 5 mg; Abbott, Türkiye) for 14 days.

    Techniques: Control

    Effects of terazosin and leuprolide acetate treatments on molecular and biochemical parameters in serum. Bar graphs illustrate the tissue concentrations of ( A ) Steroidogenic Factor-1 (SF-1), ( B ) Interleukin-8 (IL-8), ( C ) Interleukin-6 (IL-6), ( D ) Vascular Endothelial Growth Factor (VEGF), ( E ) Tumor Necrosis Factor-alpha (TNF-α), ( F ) Hypoxia-Inducible Factor-1 Alpha (HIF-1A), ( G ) Total Antioxidant Status (TAS), ( H ) Total Oxidant Status (TOS), ( I ) Oxidative Stress Index (OSI), ( J ) Nuclear Factor kappa-B (NF-κB), and ( K ) Prostaglandin E2 (PGE2). S: Sham group; E: Endometriosis control group; E + T: Endometriosis + Terazosin treatment group; E + L: Endometriosis + Leuprolide acetate treatment group.

    Journal: International Journal of Molecular Sciences

    Article Title: Terazosin as a Non-Hormonal Treatment for Endometriosis

    doi: 10.3390/ijms27094093

    Figure Lengend Snippet: Effects of terazosin and leuprolide acetate treatments on molecular and biochemical parameters in serum. Bar graphs illustrate the tissue concentrations of ( A ) Steroidogenic Factor-1 (SF-1), ( B ) Interleukin-8 (IL-8), ( C ) Interleukin-6 (IL-6), ( D ) Vascular Endothelial Growth Factor (VEGF), ( E ) Tumor Necrosis Factor-alpha (TNF-α), ( F ) Hypoxia-Inducible Factor-1 Alpha (HIF-1A), ( G ) Total Antioxidant Status (TAS), ( H ) Total Oxidant Status (TOS), ( I ) Oxidative Stress Index (OSI), ( J ) Nuclear Factor kappa-B (NF-κB), and ( K ) Prostaglandin E2 (PGE2). S: Sham group; E: Endometriosis control group; E + T: Endometriosis + Terazosin treatment group; E + L: Endometriosis + Leuprolide acetate treatment group.

    Article Snippet: Group E + T (Terazosin): Oral gavage with terazosin by dissolving the tablets in sterile saline at a daily dose of 5 mg/kg (Hytrin ® , 5 mg; Abbott, Türkiye) for 14 days.

    Techniques: Control

    Effects of terazosin and leuprolide acetate treatments on molecular and biochemical parameters in peritoneal fluid. Bar graphs illustrate the tissue concentrations of ( A ) Steroidogenic Factor-1 (SF-1), ( B ) Interleukin-8 (IL-8), ( C ) Interleukin-6 (IL-6), ( D ) Vascular Endothelial Growth Factor (VEGF), ( E ) Tumor Necrosis Factor-alpha (TNF-α), ( F ) Hypoxia-Inducible Factor-1 Alpha (HIF-1A), ( G ) Total Antioxidant Status (TAS), ( H ) Total Oxidant Status (TOS), ( I ) Oxidative Stress Index (OSI), ( J ) Nuclear Factor kappa-B (NF-κB), and ( K ) Prostaglandin E2 (PGE2). S: Sham group; E: Endometriosis control group; E + T: Endometriosis + Terazosin treatment group; E + L: Endometriosis + Leuprolide acetate treatment group.

    Journal: International Journal of Molecular Sciences

    Article Title: Terazosin as a Non-Hormonal Treatment for Endometriosis

    doi: 10.3390/ijms27094093

    Figure Lengend Snippet: Effects of terazosin and leuprolide acetate treatments on molecular and biochemical parameters in peritoneal fluid. Bar graphs illustrate the tissue concentrations of ( A ) Steroidogenic Factor-1 (SF-1), ( B ) Interleukin-8 (IL-8), ( C ) Interleukin-6 (IL-6), ( D ) Vascular Endothelial Growth Factor (VEGF), ( E ) Tumor Necrosis Factor-alpha (TNF-α), ( F ) Hypoxia-Inducible Factor-1 Alpha (HIF-1A), ( G ) Total Antioxidant Status (TAS), ( H ) Total Oxidant Status (TOS), ( I ) Oxidative Stress Index (OSI), ( J ) Nuclear Factor kappa-B (NF-κB), and ( K ) Prostaglandin E2 (PGE2). S: Sham group; E: Endometriosis control group; E + T: Endometriosis + Terazosin treatment group; E + L: Endometriosis + Leuprolide acetate treatment group.

    Article Snippet: Group E + T (Terazosin): Oral gavage with terazosin by dissolving the tablets in sterile saline at a daily dose of 5 mg/kg (Hytrin ® , 5 mg; Abbott, Türkiye) for 14 days.

    Techniques: Control