Review




Structured Review

Novartis abl kinase inhibitor sti 571
Abl Kinase Inhibitor Sti 571, supplied by Novartis, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sti-571/sti571/pmc12657980-384-10-14
Average 86 stars, based on 1 article reviews
abl kinase inhibitor sti 571 - by Bioz Stars, 2026-10
86/100 stars

Images

Related Articles

Flow Cytometry:

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: After a 24-hour transfection, cells were incubated with varying concentrations of STI-571 (provided by Novartis Pharmaceuticals, Basel, Switzerland) for 2 hours.

Article Title: Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ
Article Snippet: Purified pMX-INV v-Abl pro-B cells were treated with 3 μM of the Abl kinase inhibitor STI-571 (Novartis) for 72 h and assayed for recombination levels by FACS analysis of GFP/hCD4 expression (hCD4-PE antibody, Miltenyi 130-113-254, clone M-T466, 1:100).

Article Title: CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
Article Snippet: STI-571 , Novartis , N/A.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: As discussed in the Examples below, peripheral blood and/or bone marrow samples were obtained with appropriate informed consent from CML and Ph-positive ALL patients at UCLA who were enrolled in multicenter clinical trials of STI-571 sponsored by Novartis Pharmaceuticals.

Article Title: The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila
Article Snippet: S2 cell transfection was by standard methods using DDAB reagent (Sigma) plus 0.7-4 μg plasmid DNA.

Article Title: The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination
Article Snippet: 10 μg/mL LPS (L6529, Sigma), 2 μM CpG ODN 1826 (InvivoGen), or 2.5 μM STI-571 (Gleevec, Novartis) were added as indicated.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: To determine the biochemical sensitivity of mutant P210 isoforms to STI-571, cells were incubated in the presence of STI-571 (kindly provided by Novartis, Switzerland) at 0, 0.5, 1, 5, and 10 micromoles per liter.

Expressing:

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: After a 24-hour transfection, cells were incubated with varying concentrations of STI-571 (provided by Novartis Pharmaceuticals, Basel, Switzerland) for 2 hours.

Article Title: Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ
Article Snippet: Purified pMX-INV v-Abl pro-B cells were treated with 3 μM of the Abl kinase inhibitor STI-571 (Novartis) for 72 h and assayed for recombination levels by FACS analysis of GFP/hCD4 expression (hCD4-PE antibody, Miltenyi 130-113-254, clone M-T466, 1:100).

Article Title: CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
Article Snippet: STI-571 , Novartis , N/A.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: As discussed in the Examples below, peripheral blood and/or bone marrow samples were obtained with appropriate informed consent from CML and Ph-positive ALL patients at UCLA who were enrolled in multicenter clinical trials of STI-571 sponsored by Novartis Pharmaceuticals.

Article Title: The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila
Article Snippet: S2 cell transfection was by standard methods using DDAB reagent (Sigma) plus 0.7-4 μg plasmid DNA.

Article Title: The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination
Article Snippet: 10 μg/mL LPS (L6529, Sigma), 2 μM CpG ODN 1826 (InvivoGen), or 2.5 μM STI-571 (Gleevec, Novartis) were added as indicated.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: To determine the biochemical sensitivity of mutant P210 isoforms to STI-571, cells were incubated in the presence of STI-571 (kindly provided by Novartis, Switzerland) at 0, 0.5, 1, 5, and 10 micromoles per liter.

Northern Blot:

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: After a 24-hour transfection, cells were incubated with varying concentrations of STI-571 (provided by Novartis Pharmaceuticals, Basel, Switzerland) for 2 hours.

Article Title: Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ
Article Snippet: Purified pMX-INV v-Abl pro-B cells were treated with 3 μM of the Abl kinase inhibitor STI-571 (Novartis) for 72 h and assayed for recombination levels by FACS analysis of GFP/hCD4 expression (hCD4-PE antibody, Miltenyi 130-113-254, clone M-T466, 1:100).

Article Title: CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
Article Snippet: STI-571 , Novartis , N/A.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: As discussed in the Examples below, peripheral blood and/or bone marrow samples were obtained with appropriate informed consent from CML and Ph-positive ALL patients at UCLA who were enrolled in multicenter clinical trials of STI-571 sponsored by Novartis Pharmaceuticals.

Article Title: The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila
Article Snippet: S2 cell transfection was by standard methods using DDAB reagent (Sigma) plus 0.7-4 μg plasmid DNA.

Article Title: The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination
Article Snippet: 10 μg/mL LPS (L6529, Sigma), 2 μM CpG ODN 1826 (InvivoGen), or 2.5 μM STI-571 (Gleevec, Novartis) were added as indicated.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: To determine the biochemical sensitivity of mutant P210 isoforms to STI-571, cells were incubated in the presence of STI-571 (kindly provided by Novartis, Switzerland) at 0, 0.5, 1, 5, and 10 micromoles per liter.

Transformation Assay:

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: After a 24-hour transfection, cells were incubated with varying concentrations of STI-571 (provided by Novartis Pharmaceuticals, Basel, Switzerland) for 2 hours.

Article Title: Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ
Article Snippet: Purified pMX-INV v-Abl pro-B cells were treated with 3 μM of the Abl kinase inhibitor STI-571 (Novartis) for 72 h and assayed for recombination levels by FACS analysis of GFP/hCD4 expression (hCD4-PE antibody, Miltenyi 130-113-254, clone M-T466, 1:100).

Article Title: CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
Article Snippet: STI-571 , Novartis , N/A.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: As discussed in the Examples below, peripheral blood and/or bone marrow samples were obtained with appropriate informed consent from CML and Ph-positive ALL patients at UCLA who were enrolled in multicenter clinical trials of STI-571 sponsored by Novartis Pharmaceuticals.

Article Title: The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila
Article Snippet: S2 cell transfection was by standard methods using DDAB reagent (Sigma) plus 0.7-4 μg plasmid DNA.

Article Title: The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination
Article Snippet: 10 μg/mL LPS (L6529, Sigma), 2 μM CpG ODN 1826 (InvivoGen), or 2.5 μM STI-571 (Gleevec, Novartis) were added as indicated.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: To determine the biochemical sensitivity of mutant P210 isoforms to STI-571, cells were incubated in the presence of STI-571 (kindly provided by Novartis, Switzerland) at 0, 0.5, 1, 5, and 10 micromoles per liter.

Purification:

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: After a 24-hour transfection, cells were incubated with varying concentrations of STI-571 (provided by Novartis Pharmaceuticals, Basel, Switzerland) for 2 hours.

Article Title: Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ
Article Snippet: Purified pMX-INV v-Abl pro-B cells were treated with 3 μM of the Abl kinase inhibitor STI-571 (Novartis) for 72 h and assayed for recombination levels by FACS analysis of GFP/hCD4 expression (hCD4-PE antibody, Miltenyi 130-113-254, clone M-T466, 1:100).

Article Title: CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
Article Snippet: STI-571 , Novartis , N/A.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: As discussed in the Examples below, peripheral blood and/or bone marrow samples were obtained with appropriate informed consent from CML and Ph-positive ALL patients at UCLA who were enrolled in multicenter clinical trials of STI-571 sponsored by Novartis Pharmaceuticals.

Article Title: The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila
Article Snippet: S2 cell transfection was by standard methods using DDAB reagent (Sigma) plus 0.7-4 μg plasmid DNA.

Article Title: The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination
Article Snippet: 10 μg/mL LPS (L6529, Sigma), 2 μM CpG ODN 1826 (InvivoGen), or 2.5 μM STI-571 (Gleevec, Novartis) were added as indicated.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: To determine the biochemical sensitivity of mutant P210 isoforms to STI-571, cells were incubated in the presence of STI-571 (kindly provided by Novartis, Switzerland) at 0, 0.5, 1, 5, and 10 micromoles per liter.

FACS:

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: After a 24-hour transfection, cells were incubated with varying concentrations of STI-571 (provided by Novartis Pharmaceuticals, Basel, Switzerland) for 2 hours.

Article Title: Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ
Article Snippet: Purified pMX-INV v-Abl pro-B cells were treated with 3 μM of the Abl kinase inhibitor STI-571 (Novartis) for 72 h and assayed for recombination levels by FACS analysis of GFP/hCD4 expression (hCD4-PE antibody, Miltenyi 130-113-254, clone M-T466, 1:100).

Article Title: CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
Article Snippet: STI-571 , Novartis , N/A.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: As discussed in the Examples below, peripheral blood and/or bone marrow samples were obtained with appropriate informed consent from CML and Ph-positive ALL patients at UCLA who were enrolled in multicenter clinical trials of STI-571 sponsored by Novartis Pharmaceuticals.

Article Title: The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila
Article Snippet: S2 cell transfection was by standard methods using DDAB reagent (Sigma) plus 0.7-4 μg plasmid DNA.

Article Title: The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination
Article Snippet: 10 μg/mL LPS (L6529, Sigma), 2 μM CpG ODN 1826 (InvivoGen), or 2.5 μM STI-571 (Gleevec, Novartis) were added as indicated.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: To determine the biochemical sensitivity of mutant P210 isoforms to STI-571, cells were incubated in the presence of STI-571 (kindly provided by Novartis, Switzerland) at 0, 0.5, 1, 5, and 10 micromoles per liter.

Isolation:

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: After a 24-hour transfection, cells were incubated with varying concentrations of STI-571 (provided by Novartis Pharmaceuticals, Basel, Switzerland) for 2 hours.

Article Title: Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ
Article Snippet: Purified pMX-INV v-Abl pro-B cells were treated with 3 μM of the Abl kinase inhibitor STI-571 (Novartis) for 72 h and assayed for recombination levels by FACS analysis of GFP/hCD4 expression (hCD4-PE antibody, Miltenyi 130-113-254, clone M-T466, 1:100).

Article Title: CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
Article Snippet: STI-571 , Novartis , N/A.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: As discussed in the Examples below, peripheral blood and/or bone marrow samples were obtained with appropriate informed consent from CML and Ph-positive ALL patients at UCLA who were enrolled in multicenter clinical trials of STI-571 sponsored by Novartis Pharmaceuticals.

Article Title: The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila
Article Snippet: S2 cell transfection was by standard methods using DDAB reagent (Sigma) plus 0.7-4 μg plasmid DNA.

Article Title: The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination
Article Snippet: 10 μg/mL LPS (L6529, Sigma), 2 μM CpG ODN 1826 (InvivoGen), or 2.5 μM STI-571 (Gleevec, Novartis) were added as indicated.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: To determine the biochemical sensitivity of mutant P210 isoforms to STI-571, cells were incubated in the presence of STI-571 (kindly provided by Novartis, Switzerland) at 0, 0.5, 1, 5, and 10 micromoles per liter.

Sonication:

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: After a 24-hour transfection, cells were incubated with varying concentrations of STI-571 (provided by Novartis Pharmaceuticals, Basel, Switzerland) for 2 hours.

Article Title: Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ
Article Snippet: Purified pMX-INV v-Abl pro-B cells were treated with 3 μM of the Abl kinase inhibitor STI-571 (Novartis) for 72 h and assayed for recombination levels by FACS analysis of GFP/hCD4 expression (hCD4-PE antibody, Miltenyi 130-113-254, clone M-T466, 1:100).

Article Title: CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
Article Snippet: STI-571 , Novartis , N/A.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: As discussed in the Examples below, peripheral blood and/or bone marrow samples were obtained with appropriate informed consent from CML and Ph-positive ALL patients at UCLA who were enrolled in multicenter clinical trials of STI-571 sponsored by Novartis Pharmaceuticals.

Article Title: The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila
Article Snippet: S2 cell transfection was by standard methods using DDAB reagent (Sigma) plus 0.7-4 μg plasmid DNA.

Article Title: The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination
Article Snippet: 10 μg/mL LPS (L6529, Sigma), 2 μM CpG ODN 1826 (InvivoGen), or 2.5 μM STI-571 (Gleevec, Novartis) were added as indicated.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: To determine the biochemical sensitivity of mutant P210 isoforms to STI-571, cells were incubated in the presence of STI-571 (kindly provided by Novartis, Switzerland) at 0, 0.5, 1, 5, and 10 micromoles per liter.

Mutagenesis:

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: After a 24-hour transfection, cells were incubated with varying concentrations of STI-571 (provided by Novartis Pharmaceuticals, Basel, Switzerland) for 2 hours.

Article Title: Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ
Article Snippet: Purified pMX-INV v-Abl pro-B cells were treated with 3 μM of the Abl kinase inhibitor STI-571 (Novartis) for 72 h and assayed for recombination levels by FACS analysis of GFP/hCD4 expression (hCD4-PE antibody, Miltenyi 130-113-254, clone M-T466, 1:100).

Article Title: CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
Article Snippet: STI-571 , Novartis , N/A.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: As discussed in the Examples below, peripheral blood and/or bone marrow samples were obtained with appropriate informed consent from CML and Ph-positive ALL patients at UCLA who were enrolled in multicenter clinical trials of STI-571 sponsored by Novartis Pharmaceuticals.

Article Title: The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila
Article Snippet: S2 cell transfection was by standard methods using DDAB reagent (Sigma) plus 0.7-4 μg plasmid DNA.

Article Title: The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination
Article Snippet: 10 μg/mL LPS (L6529, Sigma), 2 μM CpG ODN 1826 (InvivoGen), or 2.5 μM STI-571 (Gleevec, Novartis) were added as indicated.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: To determine the biochemical sensitivity of mutant P210 isoforms to STI-571, cells were incubated in the presence of STI-571 (kindly provided by Novartis, Switzerland) at 0, 0.5, 1, 5, and 10 micromoles per liter.

Incubation:

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: After a 24-hour transfection, cells were incubated with varying concentrations of STI-571 (provided by Novartis Pharmaceuticals, Basel, Switzerland) for 2 hours.

Article Title: Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ
Article Snippet: Purified pMX-INV v-Abl pro-B cells were treated with 3 μM of the Abl kinase inhibitor STI-571 (Novartis) for 72 h and assayed for recombination levels by FACS analysis of GFP/hCD4 expression (hCD4-PE antibody, Miltenyi 130-113-254, clone M-T466, 1:100).

Article Title: CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
Article Snippet: STI-571 , Novartis , N/A.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: As discussed in the Examples below, peripheral blood and/or bone marrow samples were obtained with appropriate informed consent from CML and Ph-positive ALL patients at UCLA who were enrolled in multicenter clinical trials of STI-571 sponsored by Novartis Pharmaceuticals.

Article Title: The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila
Article Snippet: S2 cell transfection was by standard methods using DDAB reagent (Sigma) plus 0.7-4 μg plasmid DNA.

Article Title: The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination
Article Snippet: 10 μg/mL LPS (L6529, Sigma), 2 μM CpG ODN 1826 (InvivoGen), or 2.5 μM STI-571 (Gleevec, Novartis) were added as indicated.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: To determine the biochemical sensitivity of mutant P210 isoforms to STI-571, cells were incubated in the presence of STI-571 (kindly provided by Novartis, Switzerland) at 0, 0.5, 1, 5, and 10 micromoles per liter.

Transfection:

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: After a 24-hour transfection, cells were incubated with varying concentrations of STI-571 (provided by Novartis Pharmaceuticals, Basel, Switzerland) for 2 hours.

Article Title: Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ
Article Snippet: Purified pMX-INV v-Abl pro-B cells were treated with 3 μM of the Abl kinase inhibitor STI-571 (Novartis) for 72 h and assayed for recombination levels by FACS analysis of GFP/hCD4 expression (hCD4-PE antibody, Miltenyi 130-113-254, clone M-T466, 1:100).

Article Title: CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
Article Snippet: STI-571 , Novartis , N/A.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: As discussed in the Examples below, peripheral blood and/or bone marrow samples were obtained with appropriate informed consent from CML and Ph-positive ALL patients at UCLA who were enrolled in multicenter clinical trials of STI-571 sponsored by Novartis Pharmaceuticals.

Article Title: The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila
Article Snippet: S2 cell transfection was by standard methods using DDAB reagent (Sigma) plus 0.7-4 μg plasmid DNA.

Article Title: The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination
Article Snippet: 10 μg/mL LPS (L6529, Sigma), 2 μM CpG ODN 1826 (InvivoGen), or 2.5 μM STI-571 (Gleevec, Novartis) were added as indicated.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: To determine the biochemical sensitivity of mutant P210 isoforms to STI-571, cells were incubated in the presence of STI-571 (kindly provided by Novartis, Switzerland) at 0, 0.5, 1, 5, and 10 micromoles per liter.

Activity Assay:

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: After a 24-hour transfection, cells were incubated with varying concentrations of STI-571 (provided by Novartis Pharmaceuticals, Basel, Switzerland) for 2 hours.

Article Title: Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ
Article Snippet: Purified pMX-INV v-Abl pro-B cells were treated with 3 μM of the Abl kinase inhibitor STI-571 (Novartis) for 72 h and assayed for recombination levels by FACS analysis of GFP/hCD4 expression (hCD4-PE antibody, Miltenyi 130-113-254, clone M-T466, 1:100).

Article Title: CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
Article Snippet: STI-571 , Novartis , N/A.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: As discussed in the Examples below, peripheral blood and/or bone marrow samples were obtained with appropriate informed consent from CML and Ph-positive ALL patients at UCLA who were enrolled in multicenter clinical trials of STI-571 sponsored by Novartis Pharmaceuticals.

Article Title: The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila
Article Snippet: S2 cell transfection was by standard methods using DDAB reagent (Sigma) plus 0.7-4 μg plasmid DNA.

Article Title: The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination
Article Snippet: 10 μg/mL LPS (L6529, Sigma), 2 μM CpG ODN 1826 (InvivoGen), or 2.5 μM STI-571 (Gleevec, Novartis) were added as indicated.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: To determine the biochemical sensitivity of mutant P210 isoforms to STI-571, cells were incubated in the presence of STI-571 (kindly provided by Novartis, Switzerland) at 0, 0.5, 1, 5, and 10 micromoles per liter.

Cell Culture:

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: After a 24-hour transfection, cells were incubated with varying concentrations of STI-571 (provided by Novartis Pharmaceuticals, Basel, Switzerland) for 2 hours.

Article Title: Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ
Article Snippet: Purified pMX-INV v-Abl pro-B cells were treated with 3 μM of the Abl kinase inhibitor STI-571 (Novartis) for 72 h and assayed for recombination levels by FACS analysis of GFP/hCD4 expression (hCD4-PE antibody, Miltenyi 130-113-254, clone M-T466, 1:100).

Article Title: CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
Article Snippet: STI-571 , Novartis , N/A.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: As discussed in the Examples below, peripheral blood and/or bone marrow samples were obtained with appropriate informed consent from CML and Ph-positive ALL patients at UCLA who were enrolled in multicenter clinical trials of STI-571 sponsored by Novartis Pharmaceuticals.

Article Title: The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila
Article Snippet: S2 cell transfection was by standard methods using DDAB reagent (Sigma) plus 0.7-4 μg plasmid DNA.

Article Title: The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination
Article Snippet: 10 μg/mL LPS (L6529, Sigma), 2 μM CpG ODN 1826 (InvivoGen), or 2.5 μM STI-571 (Gleevec, Novartis) were added as indicated.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: To determine the biochemical sensitivity of mutant P210 isoforms to STI-571, cells were incubated in the presence of STI-571 (kindly provided by Novartis, Switzerland) at 0, 0.5, 1, 5, and 10 micromoles per liter.

Inhibition:

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: After a 24-hour transfection, cells were incubated with varying concentrations of STI-571 (provided by Novartis Pharmaceuticals, Basel, Switzerland) for 2 hours.

Article Title: Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ
Article Snippet: Purified pMX-INV v-Abl pro-B cells were treated with 3 μM of the Abl kinase inhibitor STI-571 (Novartis) for 72 h and assayed for recombination levels by FACS analysis of GFP/hCD4 expression (hCD4-PE antibody, Miltenyi 130-113-254, clone M-T466, 1:100).

Article Title: CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
Article Snippet: STI-571 , Novartis , N/A.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: As discussed in the Examples below, peripheral blood and/or bone marrow samples were obtained with appropriate informed consent from CML and Ph-positive ALL patients at UCLA who were enrolled in multicenter clinical trials of STI-571 sponsored by Novartis Pharmaceuticals.

Article Title: The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila
Article Snippet: S2 cell transfection was by standard methods using DDAB reagent (Sigma) plus 0.7-4 μg plasmid DNA.

Article Title: The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination
Article Snippet: 10 μg/mL LPS (L6529, Sigma), 2 μM CpG ODN 1826 (InvivoGen), or 2.5 μM STI-571 (Gleevec, Novartis) were added as indicated.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: To determine the biochemical sensitivity of mutant P210 isoforms to STI-571, cells were incubated in the presence of STI-571 (kindly provided by Novartis, Switzerland) at 0, 0.5, 1, 5, and 10 micromoles per liter.

Two Tailed Test:

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: After a 24-hour transfection, cells were incubated with varying concentrations of STI-571 (provided by Novartis Pharmaceuticals, Basel, Switzerland) for 2 hours.

Article Title: Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ
Article Snippet: Purified pMX-INV v-Abl pro-B cells were treated with 3 μM of the Abl kinase inhibitor STI-571 (Novartis) for 72 h and assayed for recombination levels by FACS analysis of GFP/hCD4 expression (hCD4-PE antibody, Miltenyi 130-113-254, clone M-T466, 1:100).

Article Title: CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
Article Snippet: STI-571 , Novartis , N/A.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: As discussed in the Examples below, peripheral blood and/or bone marrow samples were obtained with appropriate informed consent from CML and Ph-positive ALL patients at UCLA who were enrolled in multicenter clinical trials of STI-571 sponsored by Novartis Pharmaceuticals.

Article Title: The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila
Article Snippet: S2 cell transfection was by standard methods using DDAB reagent (Sigma) plus 0.7-4 μg plasmid DNA.

Article Title: The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination
Article Snippet: 10 μg/mL LPS (L6529, Sigma), 2 μM CpG ODN 1826 (InvivoGen), or 2.5 μM STI-571 (Gleevec, Novartis) were added as indicated.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: To determine the biochemical sensitivity of mutant P210 isoforms to STI-571, cells were incubated in the presence of STI-571 (kindly provided by Novartis, Switzerland) at 0, 0.5, 1, 5, and 10 micromoles per liter.

Western Blot:

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: After a 24-hour transfection, cells were incubated with varying concentrations of STI-571 (provided by Novartis Pharmaceuticals, Basel, Switzerland) for 2 hours.

Article Title: Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ
Article Snippet: Purified pMX-INV v-Abl pro-B cells were treated with 3 μM of the Abl kinase inhibitor STI-571 (Novartis) for 72 h and assayed for recombination levels by FACS analysis of GFP/hCD4 expression (hCD4-PE antibody, Miltenyi 130-113-254, clone M-T466, 1:100).

Article Title: CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
Article Snippet: STI-571 , Novartis , N/A.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: As discussed in the Examples below, peripheral blood and/or bone marrow samples were obtained with appropriate informed consent from CML and Ph-positive ALL patients at UCLA who were enrolled in multicenter clinical trials of STI-571 sponsored by Novartis Pharmaceuticals.

Article Title: The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila
Article Snippet: S2 cell transfection was by standard methods using DDAB reagent (Sigma) plus 0.7-4 μg plasmid DNA.

Article Title: The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination
Article Snippet: 10 μg/mL LPS (L6529, Sigma), 2 μM CpG ODN 1826 (InvivoGen), or 2.5 μM STI-571 (Gleevec, Novartis) were added as indicated.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: To determine the biochemical sensitivity of mutant P210 isoforms to STI-571, cells were incubated in the presence of STI-571 (kindly provided by Novartis, Switzerland) at 0, 0.5, 1, 5, and 10 micromoles per liter.

Cotransfection:

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: After a 24-hour transfection, cells were incubated with varying concentrations of STI-571 (provided by Novartis Pharmaceuticals, Basel, Switzerland) for 2 hours.

Article Title: Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ
Article Snippet: Purified pMX-INV v-Abl pro-B cells were treated with 3 μM of the Abl kinase inhibitor STI-571 (Novartis) for 72 h and assayed for recombination levels by FACS analysis of GFP/hCD4 expression (hCD4-PE antibody, Miltenyi 130-113-254, clone M-T466, 1:100).

Article Title: CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
Article Snippet: STI-571 , Novartis , N/A.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: As discussed in the Examples below, peripheral blood and/or bone marrow samples were obtained with appropriate informed consent from CML and Ph-positive ALL patients at UCLA who were enrolled in multicenter clinical trials of STI-571 sponsored by Novartis Pharmaceuticals.

Article Title: The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila
Article Snippet: S2 cell transfection was by standard methods using DDAB reagent (Sigma) plus 0.7-4 μg plasmid DNA.

Article Title: The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination
Article Snippet: 10 μg/mL LPS (L6529, Sigma), 2 μM CpG ODN 1826 (InvivoGen), or 2.5 μM STI-571 (Gleevec, Novartis) were added as indicated.

Article Title: Mutations in the Bcr-Abl tyrosine kinase associated with resistance to STI-571
Article Snippet: To determine the biochemical sensitivity of mutant P210 isoforms to STI-571, cells were incubated in the presence of STI-571 (kindly provided by Novartis, Switzerland) at 0, 0.5, 1, 5, and 10 micromoles per liter.



Similar Products

86
Novartis abl kinase inhibitor sti 571
Abl Kinase Inhibitor Sti 571, supplied by Novartis, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sti-571/sti571/pmc12657980-384-10-14
Average 86 stars, based on 1 article reviews
abl kinase inhibitor sti 571 - by Bioz Stars, 2026-10
86/100 stars
  Buy from Supplier

90
Novartis imatinib sti 571
Imatinib Sti 571, supplied by Novartis, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sti-571/imatinib/pm40451557-332-0-10
Average 90 stars, based on 1 article reviews
imatinib sti 571 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
Novartis imatinib (sti-571)
Imatinib (Sti 571), supplied by Novartis, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sti-571/imatinib/bio_rxiv__2025__03__27__645704-148-0-2
Average 90 stars, based on 1 article reviews
imatinib (sti-571) - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

96
Selleck Chemicals sti 571
Sti 571, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sti-571/Imatinib/pm39994739-64-11-13
Average 96 stars, based on 1 article reviews
sti 571 - by Bioz Stars, 2026-10
96/100 stars
  Buy from Supplier

90
Tokyo Chemical Industry sti-571
Sti 571, supplied by Tokyo Chemical Industry, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sti-571/sti+571/pmc11290492-195-13-16
Average 90 stars, based on 1 article reviews
sti-571 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
Novartis sti 571
Sti 571, supplied by Novartis, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sti-571/imatinib/pmc11201692-106-7-20
Average 90 stars, based on 1 article reviews
sti 571 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
Novartis c-abl inhibitor sti-571
C Abl Inhibitor Sti 571, supplied by Novartis, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sti-571/imatinib/pm38422699-50-19-25
Average 90 stars, based on 1 article reviews
c-abl inhibitor sti-571 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

Image Search Results