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skut1  (ATCC)


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    Structured Review

    ATCC skut1
    Degradation of CDK9 by 13 and 14 (dCDK9-202) across multiple cell lines. (A–D) Examination of dose-dependent CDK9 degradation by 13 and 14 (dCDK9-202) in TC-71, U87, <t>SKUT1,</t> and RH5. Cells were treated with increasing concentrations of indicated compounds for 6 h. (E) Effects of 22 on CDK9 protein. TC-71 cells were treated with the indicated concentration of 22 for 6 h.
    Skut1, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 152 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/skut1/product/ATCC
    Average 95 stars, based on 152 article reviews
    skut1 - by Bioz Stars, 2026-03
    95/100 stars

    Images

    1) Product Images from "Discovery of dCDK9-202 as a Highly Potent and Selective PROTAC CDK9 Degrader with Strong In Vivo Antitumor Activity"

    Article Title: Discovery of dCDK9-202 as a Highly Potent and Selective PROTAC CDK9 Degrader with Strong In Vivo Antitumor Activity

    Journal: Journal of Medicinal Chemistry

    doi: 10.1021/acs.jmedchem.5c01111

    Degradation of CDK9 by 13 and 14 (dCDK9-202) across multiple cell lines. (A–D) Examination of dose-dependent CDK9 degradation by 13 and 14 (dCDK9-202) in TC-71, U87, SKUT1, and RH5. Cells were treated with increasing concentrations of indicated compounds for 6 h. (E) Effects of 22 on CDK9 protein. TC-71 cells were treated with the indicated concentration of 22 for 6 h.
    Figure Legend Snippet: Degradation of CDK9 by 13 and 14 (dCDK9-202) across multiple cell lines. (A–D) Examination of dose-dependent CDK9 degradation by 13 and 14 (dCDK9-202) in TC-71, U87, SKUT1, and RH5. Cells were treated with increasing concentrations of indicated compounds for 6 h. (E) Effects of 22 on CDK9 protein. TC-71 cells were treated with the indicated concentration of 22 for 6 h.

    Techniques Used: Concentration Assay



    Similar Products

    skut1  (ATCC)
    95
    ATCC skut1
    Degradation of CDK9 by 13 and 14 (dCDK9-202) across multiple cell lines. (A–D) Examination of dose-dependent CDK9 degradation by 13 and 14 (dCDK9-202) in TC-71, U87, <t>SKUT1,</t> and RH5. Cells were treated with increasing concentrations of indicated compounds for 6 h. (E) Effects of 22 on CDK9 protein. TC-71 cells were treated with the indicated concentration of 22 for 6 h.
    Skut1, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/skut1/product/ATCC
    Average 95 stars, based on 1 article reviews
    skut1 - by Bioz Stars, 2026-03
    95/100 stars
    		  Buy from Supplier

    Image Search Results


    Degradation of CDK9 by 13 and 14 (dCDK9-202) across multiple cell lines. (A–D) Examination of dose-dependent CDK9 degradation by 13 and 14 (dCDK9-202) in TC-71, U87, SKUT1, and RH5. Cells were treated with increasing concentrations of indicated compounds for 6 h. (E) Effects of 22 on CDK9 protein. TC-71 cells were treated with the indicated concentration of 22 for 6 h.

    Journal: Journal of Medicinal Chemistry

    Article Title: Discovery of dCDK9-202 as a Highly Potent and Selective PROTAC CDK9 Degrader with Strong In Vivo Antitumor Activity

    doi: 10.1021/acs.jmedchem.5c01111

    Figure Lengend Snippet: Degradation of CDK9 by 13 and 14 (dCDK9-202) across multiple cell lines. (A–D) Examination of dose-dependent CDK9 degradation by 13 and 14 (dCDK9-202) in TC-71, U87, SKUT1, and RH5. Cells were treated with increasing concentrations of indicated compounds for 6 h. (E) Effects of 22 on CDK9 protein. TC-71 cells were treated with the indicated concentration of 22 for 6 h.

    Article Snippet: TC-71 (DSMZ), A673 (A-673, ATCC), SJSA-1 (ATCC), A-375 (ATCC), MES-SA (ATCC), U87 (U-87MG, ATCC), MDA-MB-231 (ATCC), and SKUT1 (SK-UT-1, ATCC) cell lines were maintained in Dulbecco’s modified Eagle’s medium (DMEM, Sigma-Aldrich).

    Techniques: Concentration Assay