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self complementary aav vector  (Addgene inc)


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    Structured Review

    Addgene inc self complementary aav vector
    Self Complementary Aav Vector, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 35 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/self+complementary+aav+vector/pscAAV-CAG-GFP+(Plasmid+%2383279)/bio_rxiv__64898__2026__10__09__757591-159-14-18
    Average 93 stars, based on 35 article reviews
    self complementary aav vector - by Bioz Stars, 2026-11
    93/100 stars

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    Related Articles

    Clone Assay:

    Article Title: Ineffective behavioral rescue despite partial brain Dp427 restoration by AAV9-U7-mediated exon 51 skipping in mdx52 mice
    Article Snippet: .. The resulting U7snRNA fragments were cloned between the inverted terminal repeats (ITRs) of a self-complementary AAV vector (pscAAV, Addgene plasmid #83279; gift from Mark Kay) for subsequent AAV production. ..

    Article Title: Ineffective behavioral rescue despite partial brain Dp427 restoration by AAV9-U7-mediated exon 51 skipping in mdx52 mice
    Article Snippet: .. The resulting U7snRNA fragments were cloned between the inverted terminal repeats (ITRs) of a self-complementary AAV vector (pscAAV, Addgene plasmid #83279; gift from Mark Kay) for subsequent AAV production. ..

    Article Title: Neonatal Delivery of Exon Skipping Therapeutics Maximizes Brain Dystrophin Rescue in the Mdx52 Mouse Model of Duchenne Muscular Dystrophy
    Article Snippet: .. The resulting U7snRNA fragments were cloned between the inverted terminal repeats (ITRs) of a self-complementary AAV vector (pscAAV, Addgene plasmid #83279; gift from Mark Kay) for subsequent AAV production. ..

    Bioprocessing:

    Article Title: Ineffective behavioral rescue despite partial brain Dp427 restoration by AAV9-U7-mediated exon 51 skipping in mdx52 mice
    Article Snippet: .. The resulting U7snRNA fragments were cloned between the inverted terminal repeats (ITRs) of a self-complementary AAV vector (pscAAV, Addgene plasmid #83279; gift from Mark Kay) for subsequent AAV production. ..

    Article Title: Ineffective behavioral rescue despite partial brain Dp427 restoration by AAV9-U7-mediated exon 51 skipping in mdx52 mice
    Article Snippet: .. The resulting U7snRNA fragments were cloned between the inverted terminal repeats (ITRs) of a self-complementary AAV vector (pscAAV, Addgene plasmid #83279; gift from Mark Kay) for subsequent AAV production. ..

    Article Title: Neonatal Delivery of Exon Skipping Therapeutics Maximizes Brain Dystrophin Rescue in the Mdx52 Mouse Model of Duchenne Muscular Dystrophy
    Article Snippet: .. The resulting U7snRNA fragments were cloned between the inverted terminal repeats (ITRs) of a self-complementary AAV vector (pscAAV, Addgene plasmid #83279; gift from Mark Kay) for subsequent AAV production. ..

    Plasmid Preparation:

    Article Title: Ineffective behavioral rescue despite partial brain Dp427 restoration by AAV9-U7-mediated exon 51 skipping in mdx52 mice
    Article Snippet: .. The resulting U7snRNA fragments were cloned between the inverted terminal repeats (ITRs) of a self-complementary AAV vector (pscAAV, Addgene plasmid #83279; gift from Mark Kay) for subsequent AAV production. ..

    Article Title: Ineffective behavioral rescue despite partial brain Dp427 restoration by AAV9-U7-mediated exon 51 skipping in mdx52 mice
    Article Snippet: .. The resulting U7snRNA fragments were cloned between the inverted terminal repeats (ITRs) of a self-complementary AAV vector (pscAAV, Addgene plasmid #83279; gift from Mark Kay) for subsequent AAV production. ..

    Article Title: Neonatal Delivery of Exon Skipping Therapeutics Maximizes Brain Dystrophin Rescue in the Mdx52 Mouse Model of Duchenne Muscular Dystrophy
    Article Snippet: .. The resulting U7snRNA fragments were cloned between the inverted terminal repeats (ITRs) of a self-complementary AAV vector (pscAAV, Addgene plasmid #83279; gift from Mark Kay) for subsequent AAV production. ..



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    Increased long-term specificity and efficiency for the minimal hIBA1a promoter when packaged in <t>scAAV</t> (A) Schematic diagram of the experimental procedure. scAAV5 virus with the hIBA1a promoter was injected into sham mice or mice with L-NIO-induced stroke. Brains were analyzed 1 week or 4 weeks later. (B) Representative confocal images showing marker expression for the indicated conditions. Scale bars, 50 μm. (C) Quantifications showing microglia-specificity of GFP expression for the indicated conditions (mean ± SEM; n = 3 mice per group). (D) Quantifications showing microglia transduction efficiency for the indicated conditions (mean ± SEM; n = 3 mice per group).
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    Image Search Results


    Increased long-term specificity and efficiency for the minimal hIBA1a promoter when packaged in scAAV (A) Schematic diagram of the experimental procedure. scAAV5 virus with the hIBA1a promoter was injected into sham mice or mice with L-NIO-induced stroke. Brains were analyzed 1 week or 4 weeks later. (B) Representative confocal images showing marker expression for the indicated conditions. Scale bars, 50 μm. (C) Quantifications showing microglia-specificity of GFP expression for the indicated conditions (mean ± SEM; n = 3 mice per group). (D) Quantifications showing microglia transduction efficiency for the indicated conditions (mean ± SEM; n = 3 mice per group).

    Journal: iScience

    Article Title: Simple and highly specific targeting of resident microglia with adeno-associated virus

    doi: 10.1016/j.isci.2024.110706

    Figure Lengend Snippet: Increased long-term specificity and efficiency for the minimal hIBA1a promoter when packaged in scAAV (A) Schematic diagram of the experimental procedure. scAAV5 virus with the hIBA1a promoter was injected into sham mice or mice with L-NIO-induced stroke. Brains were analyzed 1 week or 4 weeks later. (B) Representative confocal images showing marker expression for the indicated conditions. Scale bars, 50 μm. (C) Quantifications showing microglia-specificity of GFP expression for the indicated conditions (mean ± SEM; n = 3 mice per group). (D) Quantifications showing microglia transduction efficiency for the indicated conditions (mean ± SEM; n = 3 mice per group).

    Article Snippet: The self-complementary AAV (scAAV) vectors were based on the scAAV-CAG-GFP vector (Addgene #83279) by replacing the CAG promoter with the hIBA1 promoter.

    Techniques: Virus, Injection, Marker, Expressing, Transduction

    Journal: iScience

    Article Title: Simple and highly specific targeting of resident microglia with adeno-associated virus

    doi: 10.1016/j.isci.2024.110706

    Figure Lengend Snippet:

    Article Snippet: The self-complementary AAV (scAAV) vectors were based on the scAAV-CAG-GFP vector (Addgene #83279) by replacing the CAG promoter with the hIBA1 promoter.

    Techniques: Recombinant, Software