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sb9200  (MedChemExpress)


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    Structured Review

    MedChemExpress sb9200
    The DDX58 agonist, <t>SB9200,</t> inhibits colon cancer progression. (A and B) Effect of SB9200 on cell proliferation and viability. Cell viability and proliferation were detected using MTS and EdU assays, respectively. Representative images were obtained. Scale bars, 100 µm. * P<0.05 vs. the 0 µM SB9200 group; # P<0.05 vs. the 20 µM SB9200 group; & P<0.05 vs. the 40 µM SB9200 group; ∆ P<0.05 vs. the 80 µM SB9200 group. ∇ P<0.05 vs. the 120 µM SB9200 group. (C-F) Wound healing and Transwell assays were performed to detect the effects of SB9200 on cell migration and invasion. Representative images were obtained. Scale bars, 500 µm for wound healing assay. Scale bars, 200 µm for Transwell assay. All data are expressed as the mean ± standard deviation. * P<0.05 vs. the 0 µM SB9200 group. (G-I) Effect of SB9200 on the DDX58/pSTAT3/CSE pathway. Western blot analysis was performed to detect the level of DDX58, STAT3, pSTAT3 and CSE proteins. All data are expressed as the mean ± standard deviation. * P<0.05 vs. the 0 µM SB9200 group. DExD/H-box helicase 58; CSE, cystathionine-γ-lyase.
    Sb9200, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 91/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/sb9200/product/MedChemExpress
    Average 91 stars, based on 4 article reviews
    sb9200 - by Bioz Stars, 2026-02
    91/100 stars

    Images

    1) Product Images from "Activation of DDX58/RIG-I suppresses the growth of tumor cells by inhibiting STAT3/CSE signaling in colon cancer"

    Article Title: Activation of DDX58/RIG-I suppresses the growth of tumor cells by inhibiting STAT3/CSE signaling in colon cancer

    Journal: International Journal of Oncology

    doi: 10.3892/ijo.2022.5410

    The DDX58 agonist, SB9200, inhibits colon cancer progression. (A and B) Effect of SB9200 on cell proliferation and viability. Cell viability and proliferation were detected using MTS and EdU assays, respectively. Representative images were obtained. Scale bars, 100 µm. * P<0.05 vs. the 0 µM SB9200 group; # P<0.05 vs. the 20 µM SB9200 group; & P<0.05 vs. the 40 µM SB9200 group; ∆ P<0.05 vs. the 80 µM SB9200 group. ∇ P<0.05 vs. the 120 µM SB9200 group. (C-F) Wound healing and Transwell assays were performed to detect the effects of SB9200 on cell migration and invasion. Representative images were obtained. Scale bars, 500 µm for wound healing assay. Scale bars, 200 µm for Transwell assay. All data are expressed as the mean ± standard deviation. * P<0.05 vs. the 0 µM SB9200 group. (G-I) Effect of SB9200 on the DDX58/pSTAT3/CSE pathway. Western blot analysis was performed to detect the level of DDX58, STAT3, pSTAT3 and CSE proteins. All data are expressed as the mean ± standard deviation. * P<0.05 vs. the 0 µM SB9200 group. DExD/H-box helicase 58; CSE, cystathionine-γ-lyase.
    Figure Legend Snippet: The DDX58 agonist, SB9200, inhibits colon cancer progression. (A and B) Effect of SB9200 on cell proliferation and viability. Cell viability and proliferation were detected using MTS and EdU assays, respectively. Representative images were obtained. Scale bars, 100 µm. * P<0.05 vs. the 0 µM SB9200 group; # P<0.05 vs. the 20 µM SB9200 group; & P<0.05 vs. the 40 µM SB9200 group; ∆ P<0.05 vs. the 80 µM SB9200 group. ∇ P<0.05 vs. the 120 µM SB9200 group. (C-F) Wound healing and Transwell assays were performed to detect the effects of SB9200 on cell migration and invasion. Representative images were obtained. Scale bars, 500 µm for wound healing assay. Scale bars, 200 µm for Transwell assay. All data are expressed as the mean ± standard deviation. * P<0.05 vs. the 0 µM SB9200 group. (G-I) Effect of SB9200 on the DDX58/pSTAT3/CSE pathway. Western blot analysis was performed to detect the level of DDX58, STAT3, pSTAT3 and CSE proteins. All data are expressed as the mean ± standard deviation. * P<0.05 vs. the 0 µM SB9200 group. DExD/H-box helicase 58; CSE, cystathionine-γ-lyase.

    Techniques Used: Migration, Wound Healing Assay, Transwell Assay, Standard Deviation, Western Blot



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    sb9200  (MedChemExpress)
    91
    MedChemExpress sb9200
    The DDX58 agonist, <t>SB9200,</t> inhibits colon cancer progression. (A and B) Effect of SB9200 on cell proliferation and viability. Cell viability and proliferation were detected using MTS and EdU assays, respectively. Representative images were obtained. Scale bars, 100 µm. * P<0.05 vs. the 0 µM SB9200 group; # P<0.05 vs. the 20 µM SB9200 group; & P<0.05 vs. the 40 µM SB9200 group; ∆ P<0.05 vs. the 80 µM SB9200 group. ∇ P<0.05 vs. the 120 µM SB9200 group. (C-F) Wound healing and Transwell assays were performed to detect the effects of SB9200 on cell migration and invasion. Representative images were obtained. Scale bars, 500 µm for wound healing assay. Scale bars, 200 µm for Transwell assay. All data are expressed as the mean ± standard deviation. * P<0.05 vs. the 0 µM SB9200 group. (G-I) Effect of SB9200 on the DDX58/pSTAT3/CSE pathway. Western blot analysis was performed to detect the level of DDX58, STAT3, pSTAT3 and CSE proteins. All data are expressed as the mean ± standard deviation. * P<0.05 vs. the 0 µM SB9200 group. DExD/H-box helicase 58; CSE, cystathionine-γ-lyase.
    Sb9200, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/sb9200/product/MedChemExpress
    Average 91 stars, based on 1 article reviews
    sb9200 - by Bioz Stars, 2026-02
    91/100 stars
    		  Buy from Supplier

    Image Search Results


    The DDX58 agonist, SB9200, inhibits colon cancer progression. (A and B) Effect of SB9200 on cell proliferation and viability. Cell viability and proliferation were detected using MTS and EdU assays, respectively. Representative images were obtained. Scale bars, 100 µm. * P<0.05 vs. the 0 µM SB9200 group; # P<0.05 vs. the 20 µM SB9200 group; & P<0.05 vs. the 40 µM SB9200 group; ∆ P<0.05 vs. the 80 µM SB9200 group. ∇ P<0.05 vs. the 120 µM SB9200 group. (C-F) Wound healing and Transwell assays were performed to detect the effects of SB9200 on cell migration and invasion. Representative images were obtained. Scale bars, 500 µm for wound healing assay. Scale bars, 200 µm for Transwell assay. All data are expressed as the mean ± standard deviation. * P<0.05 vs. the 0 µM SB9200 group. (G-I) Effect of SB9200 on the DDX58/pSTAT3/CSE pathway. Western blot analysis was performed to detect the level of DDX58, STAT3, pSTAT3 and CSE proteins. All data are expressed as the mean ± standard deviation. * P<0.05 vs. the 0 µM SB9200 group. DExD/H-box helicase 58; CSE, cystathionine-γ-lyase.

    Journal: International Journal of Oncology

    Article Title: Activation of DDX58/RIG-I suppresses the growth of tumor cells by inhibiting STAT3/CSE signaling in colon cancer

    doi: 10.3892/ijo.2022.5410

    Figure Lengend Snippet: The DDX58 agonist, SB9200, inhibits colon cancer progression. (A and B) Effect of SB9200 on cell proliferation and viability. Cell viability and proliferation were detected using MTS and EdU assays, respectively. Representative images were obtained. Scale bars, 100 µm. * P<0.05 vs. the 0 µM SB9200 group; # P<0.05 vs. the 20 µM SB9200 group; & P<0.05 vs. the 40 µM SB9200 group; ∆ P<0.05 vs. the 80 µM SB9200 group. ∇ P<0.05 vs. the 120 µM SB9200 group. (C-F) Wound healing and Transwell assays were performed to detect the effects of SB9200 on cell migration and invasion. Representative images were obtained. Scale bars, 500 µm for wound healing assay. Scale bars, 200 µm for Transwell assay. All data are expressed as the mean ± standard deviation. * P<0.05 vs. the 0 µM SB9200 group. (G-I) Effect of SB9200 on the DDX58/pSTAT3/CSE pathway. Western blot analysis was performed to detect the level of DDX58, STAT3, pSTAT3 and CSE proteins. All data are expressed as the mean ± standard deviation. * P<0.05 vs. the 0 µM SB9200 group. DExD/H-box helicase 58; CSE, cystathionine-γ-lyase.

    Article Snippet: SB9200 was obtained from MedChemExpress (inarigivir soproxil, cat. no. HY-109035).

    Techniques: Migration, Wound Healing Assay, Transwell Assay, Standard Deviation, Western Blot