pi3k akt signaling pathways (MedChemExpress)
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pi3k akt signaling pathways
Pi3k Akt Signaling Pathways, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rantes/RANTES%2FCCL5%2C+Human/pmc13251122-51-9-27
Average 93 stars, based on 4 article reviews
Pi3k Akt Signaling Pathways, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rantes/RANTES%2FCCL5%2C+Human/pmc13251122-51-9-27
Average 93 stars, based on 4 article reviews
pi3k akt signaling pathways - by Bioz Stars,
2026-10
93/100 stars
Images
1) Product Images from "Targeting the CCL5/CCR5-PI3K-AKT axis suppresses hepatic stellate cell-induced breast cancer metastasis"
Article Title: Targeting the CCL5/CCR5-PI3K-AKT axis suppresses hepatic stellate cell-induced breast cancer metastasis
Journal: Cancer Cell International
doi: 10.1186/s12935-026-04295-2
Figure Legend Snippet: Influence of LX-2 Cells on MDA-MB-231 Cells through CCL5. Note: ( A ) Schematic representation of the cell experiment process; ( B ) CCK-8 experiment assessing changes in cell proliferation in each group; 100 µL of conditioned medium (CM) per well; ( C ) Scratch assay examining cell migration ability in each group with statistical analysis (scale bar: 100 μm); 2 mL of CM per well; ( D ) Transwell assay measuring cell invasion ability in each group (scale bar: 50 μm); 200 µL of CM per well; ( E ) WB analysis of EMT marker proteins E-cadherin, N-cadherin, and Vimentin, and PI3K-AKT pathway protein expression changes; 2 mL of CM per well. CM: condition medium.* P < 0.05, with all cell experiments repeated three times
Techniques Used: CCK-8 Assay, Wound Healing Assay, Migration, Transwell Assay, Marker, Expressing
Figure Legend Snippet: Impact of CCR5 and PI3K-AKT Pathway Inhibition on MDA-MB-231 Cells. Note: ( A ) CCK-8 experiment evaluating changes in cell proliferation in each group; ( B ) Scratch assay assessing cell migration ability in each group with statistical representation (scale bar: 100 μm); ( C ) Transwell assay measuring cell invasion ability in each group (scale bar: 50 μm); ( D ) WB analysis of EMT marker proteins E-cadherin, N-cadherin, and Vimentin, and PI3K-AKT pathway protein expression changes. * P < 0.05, with all cell experiments repeated three times
Techniques Used: Inhibition, CCK-8 Assay, Wound Healing Assay, Migration, Transwell Assay, Marker, Expressing
Figure Legend Snippet: CCL5 Derived from HSCs Activates the PI3K-AKT Pathway through the CCL5/CCR5 Axis to Promote the Invasion and Metastasis of Breast Cancer Cells
Techniques Used: Derivative Assay
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Recombinant:Article Title: CCL5 deficiency aggravates acute DSS-induced colitis by restricting IL-33-induced formation of Tregs in intestinal tract Article Snippet: .. To rescue the phenotypes of enteritis, Article Title: Nuclear Factor I-B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription. Article Snippet: Prior to TGF- β (2 ng/mL; #246-LP-025; R&D System, Minneapolis, MN, USA) stimulation, LX-2 cells were subjected to an overnight serum starvation, which imitated HSC activation in vitro [ 48 ]. .. During certain experiments, Injection:Article Title: CCL5 deficiency aggravates acute DSS-induced colitis by restricting IL-33-induced formation of Tregs in intestinal tract Article Snippet: .. To rescue the phenotypes of enteritis, Concentration Assay:Article Title: CCL5 deficiency aggravates acute DSS-induced colitis by restricting IL-33-induced formation of Tregs in intestinal tract Article Snippet: .. To rescue the phenotypes of enteritis, Protein-Protein interactions:Article Title: Targeting the CCL5/CCR5-PI3K-AKT axis suppresses hepatic stellate cell-induced breast cancer metastasis Article Snippet: All cell lines were maintained in a 37 °C, 5% CO 2 incubator (HeracellTM Vios 160i CR CO 2 incubator, 51033770, Thermo ScientificTM, Germany). .. To investigate the impact of the CCL5, CCR5, and Article Title: Targeting the CCL5/CCR5-PI3K-AKT axis suppresses hepatic stellate cell-induced breast cancer metastasis. Article Snippet: All cell lines were maintained in a 37°C, 5% CO2 incubator (HeracellTM Vios 160i CR CO2 incubator, 51033770, Thermo ScientificTM, Germany). .. To investigate the impact of the CCL5, CCR5, and PI3K-AKT signaling pathways on BC cells, during the cell culture process, cells were treated with 10 ng/ml CCL5 (MCE, HY-P7282), 100 nM Cell Culture:Article Title: Targeting the CCL5/CCR5-PI3K-AKT axis suppresses hepatic stellate cell-induced breast cancer metastasis Article Snippet: All cell lines were maintained in a 37 °C, 5% CO 2 incubator (HeracellTM Vios 160i CR CO 2 incubator, 51033770, Thermo ScientificTM, Germany). .. To investigate the impact of the CCL5, CCR5, and Article Title: Targeting the CCL5/CCR5-PI3K-AKT axis suppresses hepatic stellate cell-induced breast cancer metastasis. Article Snippet: All cell lines were maintained in a 37°C, 5% CO2 incubator (HeracellTM Vios 160i CR CO2 incubator, 51033770, Thermo ScientificTM, Germany). .. To investigate the impact of the CCL5, CCR5, and PI3K-AKT signaling pathways on BC cells, during the cell culture process, cells were treated with 10 ng/ml CCL5 (MCE, HY-P7282), 100 nM |