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proteome  (ATCC)


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    Structured Review

    ATCC proteome
    A ) Venn diagram of unique proteins identified in the in vitro cellular <t>proteome</t> (purple; 2767 proteins) and secretome (blue; 18 proteins) with 25 proteins commonly detected. B) Egg diagram of proteins identified from the host, Mus musculus (4,952 after valid value filtering), and pathogen, <t>Cryptococcus</t> <t>neoformans</t> (874 after valid value filtering) from infectome analysis. C) Principal component analysis of infectome experiment. D) Volcano plot for comparison of host proteins with significant differences in abundance between infected (teal) and uninfected (grey) conditions. Student’s t test, P < 0.05; FDR = 0.05; S 0 = 1. E) Comparison of significantly different fungal proteins identified from the in vitro cellular proteome compared to the infectome. F) Comparison of significantly different fungal proteins identified from the in vitro secretome compared to the infectome. Red lines represent 0-, 4-, and 16-fold change in protein abundance. G) Pie chart based on GOBP for 53 fungal infection-associated protein (percentage of each category represented). Experiment completed in biological triplicate.
    Proteome, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1339 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/proteome/product/ATCC
    Average 97 stars, based on 1339 article reviews
    proteome - by Bioz Stars, 2026-03
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    Images

    1) Product Images from "Systematic Infectome–Phenome Profiling Reveals Cryptococcal Infection-Associated Proteins Driving Immune System Remodeling and Immunization Potential"

    Article Title: Systematic Infectome–Phenome Profiling Reveals Cryptococcal Infection-Associated Proteins Driving Immune System Remodeling and Immunization Potential

    Journal: bioRxiv

    doi: 10.64898/2026.01.30.702846

    A ) Venn diagram of unique proteins identified in the in vitro cellular proteome (purple; 2767 proteins) and secretome (blue; 18 proteins) with 25 proteins commonly detected. B) Egg diagram of proteins identified from the host, Mus musculus (4,952 after valid value filtering), and pathogen, Cryptococcus neoformans (874 after valid value filtering) from infectome analysis. C) Principal component analysis of infectome experiment. D) Volcano plot for comparison of host proteins with significant differences in abundance between infected (teal) and uninfected (grey) conditions. Student’s t test, P < 0.05; FDR = 0.05; S 0 = 1. E) Comparison of significantly different fungal proteins identified from the in vitro cellular proteome compared to the infectome. F) Comparison of significantly different fungal proteins identified from the in vitro secretome compared to the infectome. Red lines represent 0-, 4-, and 16-fold change in protein abundance. G) Pie chart based on GOBP for 53 fungal infection-associated protein (percentage of each category represented). Experiment completed in biological triplicate.
    Figure Legend Snippet: A ) Venn diagram of unique proteins identified in the in vitro cellular proteome (purple; 2767 proteins) and secretome (blue; 18 proteins) with 25 proteins commonly detected. B) Egg diagram of proteins identified from the host, Mus musculus (4,952 after valid value filtering), and pathogen, Cryptococcus neoformans (874 after valid value filtering) from infectome analysis. C) Principal component analysis of infectome experiment. D) Volcano plot for comparison of host proteins with significant differences in abundance between infected (teal) and uninfected (grey) conditions. Student’s t test, P < 0.05; FDR = 0.05; S 0 = 1. E) Comparison of significantly different fungal proteins identified from the in vitro cellular proteome compared to the infectome. F) Comparison of significantly different fungal proteins identified from the in vitro secretome compared to the infectome. Red lines represent 0-, 4-, and 16-fold change in protein abundance. G) Pie chart based on GOBP for 53 fungal infection-associated protein (percentage of each category represented). Experiment completed in biological triplicate.

    Techniques Used: In Vitro, Comparison, Infection, Quantitative Proteomics



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    ATCC proteome
    A ) Venn diagram of unique proteins identified in the in vitro cellular <t>proteome</t> (purple; 2767 proteins) and secretome (blue; 18 proteins) with 25 proteins commonly detected. B) Egg diagram of proteins identified from the host, Mus musculus (4,952 after valid value filtering), and pathogen, <t>Cryptococcus</t> <t>neoformans</t> (874 after valid value filtering) from infectome analysis. C) Principal component analysis of infectome experiment. D) Volcano plot for comparison of host proteins with significant differences in abundance between infected (teal) and uninfected (grey) conditions. Student’s t test, P < 0.05; FDR = 0.05; S 0 = 1. E) Comparison of significantly different fungal proteins identified from the in vitro cellular proteome compared to the infectome. F) Comparison of significantly different fungal proteins identified from the in vitro secretome compared to the infectome. Red lines represent 0-, 4-, and 16-fold change in protein abundance. G) Pie chart based on GOBP for 53 fungal infection-associated protein (percentage of each category represented). Experiment completed in biological triplicate.
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    A ) Venn diagram of unique proteins identified in the in vitro cellular <t>proteome</t> (purple; 2767 proteins) and secretome (blue; 18 proteins) with 25 proteins commonly detected. B) Egg diagram of proteins identified from the host, Mus musculus (4,952 after valid value filtering), and pathogen, <t>Cryptococcus</t> <t>neoformans</t> (874 after valid value filtering) from infectome analysis. C) Principal component analysis of infectome experiment. D) Volcano plot for comparison of host proteins with significant differences in abundance between infected (teal) and uninfected (grey) conditions. Student’s t test, P < 0.05; FDR = 0.05; S 0 = 1. E) Comparison of significantly different fungal proteins identified from the in vitro cellular proteome compared to the infectome. F) Comparison of significantly different fungal proteins identified from the in vitro secretome compared to the infectome. Red lines represent 0-, 4-, and 16-fold change in protein abundance. G) Pie chart based on GOBP for 53 fungal infection-associated protein (percentage of each category represented). Experiment completed in biological triplicate.
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    A ) Venn diagram of unique proteins identified in the in vitro cellular <t>proteome</t> (purple; 2767 proteins) and secretome (blue; 18 proteins) with 25 proteins commonly detected. B) Egg diagram of proteins identified from the host, Mus musculus (4,952 after valid value filtering), and pathogen, <t>Cryptococcus</t> <t>neoformans</t> (874 after valid value filtering) from infectome analysis. C) Principal component analysis of infectome experiment. D) Volcano plot for comparison of host proteins with significant differences in abundance between infected (teal) and uninfected (grey) conditions. Student’s t test, P < 0.05; FDR = 0.05; S 0 = 1. E) Comparison of significantly different fungal proteins identified from the in vitro cellular proteome compared to the infectome. F) Comparison of significantly different fungal proteins identified from the in vitro secretome compared to the infectome. Red lines represent 0-, 4-, and 16-fold change in protein abundance. G) Pie chart based on GOBP for 53 fungal infection-associated protein (percentage of each category represented). Experiment completed in biological triplicate.
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    A ) Venn diagram of unique proteins identified in the in vitro cellular <t>proteome</t> (purple; 2767 proteins) and secretome (blue; 18 proteins) with 25 proteins commonly detected. B) Egg diagram of proteins identified from the host, Mus musculus (4,952 after valid value filtering), and pathogen, <t>Cryptococcus</t> <t>neoformans</t> (874 after valid value filtering) from infectome analysis. C) Principal component analysis of infectome experiment. D) Volcano plot for comparison of host proteins with significant differences in abundance between infected (teal) and uninfected (grey) conditions. Student’s t test, P < 0.05; FDR = 0.05; S 0 = 1. E) Comparison of significantly different fungal proteins identified from the in vitro cellular proteome compared to the infectome. F) Comparison of significantly different fungal proteins identified from the in vitro secretome compared to the infectome. Red lines represent 0-, 4-, and 16-fold change in protein abundance. G) Pie chart based on GOBP for 53 fungal infection-associated protein (percentage of each category represented). Experiment completed in biological triplicate.
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    ATCC proteome sequence fasta files
    A ) Venn diagram of unique proteins identified in the in vitro cellular <t>proteome</t> (purple; 2767 proteins) and secretome (blue; 18 proteins) with 25 proteins commonly detected. B) Egg diagram of proteins identified from the host, Mus musculus (4,952 after valid value filtering), and pathogen, <t>Cryptococcus</t> <t>neoformans</t> (874 after valid value filtering) from infectome analysis. C) Principal component analysis of infectome experiment. D) Volcano plot for comparison of host proteins with significant differences in abundance between infected (teal) and uninfected (grey) conditions. Student’s t test, P < 0.05; FDR = 0.05; S 0 = 1. E) Comparison of significantly different fungal proteins identified from the in vitro cellular proteome compared to the infectome. F) Comparison of significantly different fungal proteins identified from the in vitro secretome compared to the infectome. Red lines represent 0-, 4-, and 16-fold change in protein abundance. G) Pie chart based on GOBP for 53 fungal infection-associated protein (percentage of each category represented). Experiment completed in biological triplicate.
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    A ) Venn diagram of unique proteins identified in the in vitro cellular <t>proteome</t> (purple; 2767 proteins) and secretome (blue; 18 proteins) with 25 proteins commonly detected. B) Egg diagram of proteins identified from the host, Mus musculus (4,952 after valid value filtering), and pathogen, <t>Cryptococcus</t> <t>neoformans</t> (874 after valid value filtering) from infectome analysis. C) Principal component analysis of infectome experiment. D) Volcano plot for comparison of host proteins with significant differences in abundance between infected (teal) and uninfected (grey) conditions. Student’s t test, P < 0.05; FDR = 0.05; S 0 = 1. E) Comparison of significantly different fungal proteins identified from the in vitro cellular proteome compared to the infectome. F) Comparison of significantly different fungal proteins identified from the in vitro secretome compared to the infectome. Red lines represent 0-, 4-, and 16-fold change in protein abundance. G) Pie chart based on GOBP for 53 fungal infection-associated protein (percentage of each category represented). Experiment completed in biological triplicate.
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    A ) Venn diagram of unique proteins identified in the in vitro cellular <t>proteome</t> (purple; 2767 proteins) and secretome (blue; 18 proteins) with 25 proteins commonly detected. B) Egg diagram of proteins identified from the host, Mus musculus (4,952 after valid value filtering), and pathogen, <t>Cryptococcus</t> <t>neoformans</t> (874 after valid value filtering) from infectome analysis. C) Principal component analysis of infectome experiment. D) Volcano plot for comparison of host proteins with significant differences in abundance between infected (teal) and uninfected (grey) conditions. Student’s t test, P < 0.05; FDR = 0.05; S 0 = 1. E) Comparison of significantly different fungal proteins identified from the in vitro cellular proteome compared to the infectome. F) Comparison of significantly different fungal proteins identified from the in vitro secretome compared to the infectome. Red lines represent 0-, 4-, and 16-fold change in protein abundance. G) Pie chart based on GOBP for 53 fungal infection-associated protein (percentage of each category represented). Experiment completed in biological triplicate.
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    Image Search Results


    A ) Venn diagram of unique proteins identified in the in vitro cellular proteome (purple; 2767 proteins) and secretome (blue; 18 proteins) with 25 proteins commonly detected. B) Egg diagram of proteins identified from the host, Mus musculus (4,952 after valid value filtering), and pathogen, Cryptococcus neoformans (874 after valid value filtering) from infectome analysis. C) Principal component analysis of infectome experiment. D) Volcano plot for comparison of host proteins with significant differences in abundance between infected (teal) and uninfected (grey) conditions. Student’s t test, P < 0.05; FDR = 0.05; S 0 = 1. E) Comparison of significantly different fungal proteins identified from the in vitro cellular proteome compared to the infectome. F) Comparison of significantly different fungal proteins identified from the in vitro secretome compared to the infectome. Red lines represent 0-, 4-, and 16-fold change in protein abundance. G) Pie chart based on GOBP for 53 fungal infection-associated protein (percentage of each category represented). Experiment completed in biological triplicate.

    Journal: bioRxiv

    Article Title: Systematic Infectome–Phenome Profiling Reveals Cryptococcal Infection-Associated Proteins Driving Immune System Remodeling and Immunization Potential

    doi: 10.64898/2026.01.30.702846

    Figure Lengend Snippet: A ) Venn diagram of unique proteins identified in the in vitro cellular proteome (purple; 2767 proteins) and secretome (blue; 18 proteins) with 25 proteins commonly detected. B) Egg diagram of proteins identified from the host, Mus musculus (4,952 after valid value filtering), and pathogen, Cryptococcus neoformans (874 after valid value filtering) from infectome analysis. C) Principal component analysis of infectome experiment. D) Volcano plot for comparison of host proteins with significant differences in abundance between infected (teal) and uninfected (grey) conditions. Student’s t test, P < 0.05; FDR = 0.05; S 0 = 1. E) Comparison of significantly different fungal proteins identified from the in vitro cellular proteome compared to the infectome. F) Comparison of significantly different fungal proteins identified from the in vitro secretome compared to the infectome. Red lines represent 0-, 4-, and 16-fold change in protein abundance. G) Pie chart based on GOBP for 53 fungal infection-associated protein (percentage of each category represented). Experiment completed in biological triplicate.

    Article Snippet: The derived peak list was incorporated with the Andromeda search engine against the reference C. neoformans var. grubii serotype A (strain H99/ATCC 208821) proteome (7430 sequences; Oct. 2018) and Mus musculus (55,462 sequences; Oct 2018) from Uniprot .

    Techniques: In Vitro, Comparison, Infection, Quantitative Proteomics