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piribedil  (MedChemExpress)


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    Structured Review

    MedChemExpress piribedil
    a , Genome browser snapshots from four species, with genomic coordinates indicated at the top. RNA-seq (displayed for both positive and negative strands) and ChIP–seq datasets are normalized using reads per million (RPM). Non-stranded RNA-seq data are shown as a single track. For Chlamydomonas reinhardtii , RNA polymerase II ChIP–seq data are also displayed. b , Western blot analysis showing total histone H3 and H3K4me3 modifications in A. castellanii cells treated with the H3K4me3 inhibitors OICR-9429 and <t>Piribedil.</t> Equal amounts of total protein were loaded in each well. This experiment was repeated twice. c , Average 6mA at ApT (%) levels measured on H3K4me3 peaks in wild-type cells, comparing OICR-9429 treatment versus control and Piribedil versus control. DMSO concentrations for controls are matched to the final DMSO levels in the inhibitor samples. d , Global 6mA at ApT (%) levels in each sample as described in c .
    Piribedil, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 91/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/piribedil/product/MedChemExpress
    Average 91 stars, based on 2 article reviews
    piribedil - by Bioz Stars, 2026-02
    91/100 stars

    Images

    1) Product Images from "Adenine DNA methylation associated with transcriptionally permissive chromatin is widespread across eukaryotes"

    Article Title: Adenine DNA methylation associated with transcriptionally permissive chromatin is widespread across eukaryotes

    Journal: Nature Genetics

    doi: 10.1038/s41588-025-02409-6

    a , Genome browser snapshots from four species, with genomic coordinates indicated at the top. RNA-seq (displayed for both positive and negative strands) and ChIP–seq datasets are normalized using reads per million (RPM). Non-stranded RNA-seq data are shown as a single track. For Chlamydomonas reinhardtii , RNA polymerase II ChIP–seq data are also displayed. b , Western blot analysis showing total histone H3 and H3K4me3 modifications in A. castellanii cells treated with the H3K4me3 inhibitors OICR-9429 and Piribedil. Equal amounts of total protein were loaded in each well. This experiment was repeated twice. c , Average 6mA at ApT (%) levels measured on H3K4me3 peaks in wild-type cells, comparing OICR-9429 treatment versus control and Piribedil versus control. DMSO concentrations for controls are matched to the final DMSO levels in the inhibitor samples. d , Global 6mA at ApT (%) levels in each sample as described in c .
    Figure Legend Snippet: a , Genome browser snapshots from four species, with genomic coordinates indicated at the top. RNA-seq (displayed for both positive and negative strands) and ChIP–seq datasets are normalized using reads per million (RPM). Non-stranded RNA-seq data are shown as a single track. For Chlamydomonas reinhardtii , RNA polymerase II ChIP–seq data are also displayed. b , Western blot analysis showing total histone H3 and H3K4me3 modifications in A. castellanii cells treated with the H3K4me3 inhibitors OICR-9429 and Piribedil. Equal amounts of total protein were loaded in each well. This experiment was repeated twice. c , Average 6mA at ApT (%) levels measured on H3K4me3 peaks in wild-type cells, comparing OICR-9429 treatment versus control and Piribedil versus control. DMSO concentrations for controls are matched to the final DMSO levels in the inhibitor samples. d , Global 6mA at ApT (%) levels in each sample as described in c .

    Techniques Used: RNA Sequencing, ChIP-sequencing, Western Blot, Control



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    a , Genome browser snapshots from four species, with genomic coordinates indicated at the top. RNA-seq (displayed for both positive and negative strands) and ChIP–seq datasets are normalized using reads per million (RPM). Non-stranded RNA-seq data are shown as a single track. For Chlamydomonas reinhardtii , RNA polymerase II ChIP–seq data are also displayed. b , Western blot analysis showing total histone H3 and H3K4me3 modifications in A. castellanii cells treated with the H3K4me3 inhibitors OICR-9429 and <t>Piribedil.</t> Equal amounts of total protein were loaded in each well. This experiment was repeated twice. c , Average 6mA at ApT (%) levels measured on H3K4me3 peaks in wild-type cells, comparing OICR-9429 treatment versus control and Piribedil versus control. DMSO concentrations for controls are matched to the final DMSO levels in the inhibitor samples. d , Global 6mA at ApT (%) levels in each sample as described in c .
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    Image Search Results


    a , Genome browser snapshots from four species, with genomic coordinates indicated at the top. RNA-seq (displayed for both positive and negative strands) and ChIP–seq datasets are normalized using reads per million (RPM). Non-stranded RNA-seq data are shown as a single track. For Chlamydomonas reinhardtii , RNA polymerase II ChIP–seq data are also displayed. b , Western blot analysis showing total histone H3 and H3K4me3 modifications in A. castellanii cells treated with the H3K4me3 inhibitors OICR-9429 and Piribedil. Equal amounts of total protein were loaded in each well. This experiment was repeated twice. c , Average 6mA at ApT (%) levels measured on H3K4me3 peaks in wild-type cells, comparing OICR-9429 treatment versus control and Piribedil versus control. DMSO concentrations for controls are matched to the final DMSO levels in the inhibitor samples. d , Global 6mA at ApT (%) levels in each sample as described in c .

    Journal: Nature Genetics

    Article Title: Adenine DNA methylation associated with transcriptionally permissive chromatin is widespread across eukaryotes

    doi: 10.1038/s41588-025-02409-6

    Figure Lengend Snippet: a , Genome browser snapshots from four species, with genomic coordinates indicated at the top. RNA-seq (displayed for both positive and negative strands) and ChIP–seq datasets are normalized using reads per million (RPM). Non-stranded RNA-seq data are shown as a single track. For Chlamydomonas reinhardtii , RNA polymerase II ChIP–seq data are also displayed. b , Western blot analysis showing total histone H3 and H3K4me3 modifications in A. castellanii cells treated with the H3K4me3 inhibitors OICR-9429 and Piribedil. Equal amounts of total protein were loaded in each well. This experiment was repeated twice. c , Average 6mA at ApT (%) levels measured on H3K4me3 peaks in wild-type cells, comparing OICR-9429 treatment versus control and Piribedil versus control. DMSO concentrations for controls are matched to the final DMSO levels in the inhibitor samples. d , Global 6mA at ApT (%) levels in each sample as described in c .

    Article Snippet: Histone H3K4me3 suppression drugs OICR-9424 (MedChemExpress, HY-16993) and Piribedil (Cayman Chemical, 3605-01-4) were diluted in DMSO at 50 mM and 100 mM, respectively, as stock solutions.

    Techniques: RNA Sequencing, ChIP-sequencing, Western Blot, Control

    Summary of articles included in quantitative Synthesis.

    Journal: Heliyon

    Article Title: Treatment of apathy in Parkinson's disease: A bayesian network meta-analysis of randomised controlled trials

    doi: 10.1016/j.heliyon.2024.e26107

    Figure Lengend Snippet: Summary of articles included in quantitative Synthesis.

    Article Snippet: Thobois et al., 2013 [ ] , Piribedil, taken orally at dosages up to 300 mg daily , Placebo , 12 weeks , 19/18 , 59 ± 7/56 ± 8 , 47.4/38.9 , 12 ± 4/11 ± 3 , SAS , 21.1 ± 4.8/18.9 ± 4.2 , Low.

    Techniques: Control

    Medication evaluation for appropriateness for enteral tube administration, presence of drug–nutrient interactions, and availability of liquid formulation in the Saudi MOH formulary.

    Journal: Saudi Pharmaceutical Journal : SPJ

    Article Title: Unraveling medication errors in enteral tube administration: A cross-sectional study in geriatric patients receiving home health care

    doi: 10.1016/j.jsps.2023.101938

    Figure Lengend Snippet: Medication evaluation for appropriateness for enteral tube administration, presence of drug–nutrient interactions, and availability of liquid formulation in the Saudi MOH formulary.

    Article Snippet: , 6 , Piribedil , Trivastal® , – , No data available from the literature, medication leaflet or Micromedex.

    Techniques: Formulation, Modification

    Evaluation of drug-nutrient interactions.

    Journal: Saudi Pharmaceutical Journal : SPJ

    Article Title: Unraveling medication errors in enteral tube administration: A cross-sectional study in geriatric patients receiving home health care

    doi: 10.1016/j.jsps.2023.101938

    Figure Lengend Snippet: Evaluation of drug-nutrient interactions.

    Article Snippet: , 6 , Piribedil , Trivastal® , – , No data available from the literature, medication leaflet or Micromedex.

    Techniques: Medications

    Distribution of medications based on causes of medication error.

    Journal: Saudi Pharmaceutical Journal : SPJ

    Article Title: Unraveling medication errors in enteral tube administration: A cross-sectional study in geriatric patients receiving home health care

    doi: 10.1016/j.jsps.2023.101938

    Figure Lengend Snippet: Distribution of medications based on causes of medication error.

    Article Snippet: , 6 , Piribedil , Trivastal® , – , No data available from the literature, medication leaflet or Micromedex.

    Techniques: Medications, Formulation

    Distribution of medications administered to patients with enteral feeding.

    Journal: Saudi Pharmaceutical Journal : SPJ

    Article Title: Unraveling medication errors in enteral tube administration: A cross-sectional study in geriatric patients receiving home health care

    doi: 10.1016/j.jsps.2023.101938

    Figure Lengend Snippet: Distribution of medications administered to patients with enteral feeding.

    Article Snippet: , 6 , Piribedil , Trivastal® , – , No data available from the literature, medication leaflet or Micromedex.

    Techniques: Medications

    Distribution of medications involved in medications error.

    Journal: Saudi Pharmaceutical Journal : SPJ

    Article Title: Unraveling medication errors in enteral tube administration: A cross-sectional study in geriatric patients receiving home health care

    doi: 10.1016/j.jsps.2023.101938

    Figure Lengend Snippet: Distribution of medications involved in medications error.

    Article Snippet: , 6 , Piribedil , Trivastal® , – , No data available from the literature, medication leaflet or Micromedex.

    Techniques: Medications

    Journal: Cell Reports Methods

    Article Title: Social behavioral profiling by unsupervised deep learning reveals a stimulative effect of dopamine D3 agonists on zebrafish sociality

    doi: 10.1016/j.crmeth.2022.100381

    Figure Lengend Snippet:

    Article Snippet: Piribedil , Selleck Chemicals , S3656.

    Techniques: Recombinant, Drug discovery, Software