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pirfenidone  (MedChemExpress)


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    Structured Review

    MedChemExpress pirfenidone
    Pirfenidone, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 74 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pirfenidone/Pirfenidone/pm42580541-175-0-7
    Average 95 stars, based on 74 article reviews
    pirfenidone - by Bioz Stars, 2026-10
    95/100 stars

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    Related Articles

    Biomarker Discovery:

    Article Title: Quzhou Aurantii Fructus Extract Attenuates Idiopathic Pulmonary Fibrosis by Regulating Nrf2/HO-1 Axis.
    Article Snippet: .. Based on this validation, four days later (i.e., day 14 after intratracheal instillation of BLM), the remaining animals were randomly assigned to equally sized groups (n = 6 in each group), including control group, model group, low-dose QAFE (QAFE-L, 0.608 g/kg, i.g.), medium-dose QAFE group (QAFE-M, 1.216 g/kg, i.g.), highdose QAFE group (QAFE-H, 2.432 g/kg, i.g.), and pirfenidone group (PFD, 200 mg/kg, i.g., MCE), with pirfenidone as the positive control. ..

    Control:

    Article Title: Quzhou Aurantii Fructus Extract Attenuates Idiopathic Pulmonary Fibrosis by Regulating Nrf2/HO-1 Axis.
    Article Snippet: .. Based on this validation, four days later (i.e., day 14 after intratracheal instillation of BLM), the remaining animals were randomly assigned to equally sized groups (n = 6 in each group), including control group, model group, low-dose QAFE (QAFE-L, 0.608 g/kg, i.g.), medium-dose QAFE group (QAFE-M, 1.216 g/kg, i.g.), highdose QAFE group (QAFE-H, 2.432 g/kg, i.g.), and pirfenidone group (PFD, 200 mg/kg, i.g., MCE), with pirfenidone as the positive control. ..

    Article Title: Decoding and Targeting Coordinated CDKN1A and CDKN2A Senescence Programs in ECM-Dominant Cardiovascular Pathologies
    Article Snippet: For IL-1β neutralization, mice were treated with either an isotype control antibody (Bio X Cell, BE0091) or an anti-IL-1β neutralizing antibody (Bio X Cell, BE0246) at a dose of 5 mg/kg by intraperitoneal injection every three days , . .. Pirfenidone (MedChemExpress; 300 mg/kg) or vehicle control was administered by oral gavage once daily as previously described . ..

    Article Title: Proof-of-Concept Evaluation of Primary Human FAP-CAR-NK Cells Targeting Activated Fibroblasts in Pulmonary Fibrosis
    Article Snippet: .. Pirfenidone was included as a pharmacological antifibrotic control at 50 μM (MCE, #HY-B0673). ..

    Positive Control:

    Article Title: Quzhou Aurantii Fructus Extract Attenuates Idiopathic Pulmonary Fibrosis by Regulating Nrf2/HO-1 Axis.
    Article Snippet: .. Based on this validation, four days later (i.e., day 14 after intratracheal instillation of BLM), the remaining animals were randomly assigned to equally sized groups (n = 6 in each group), including control group, model group, low-dose QAFE (QAFE-L, 0.608 g/kg, i.g.), medium-dose QAFE group (QAFE-M, 1.216 g/kg, i.g.), highdose QAFE group (QAFE-H, 2.432 g/kg, i.g.), and pirfenidone group (PFD, 200 mg/kg, i.g., MCE), with pirfenidone as the positive control. ..

    Article Title: Cordyceps militaris granules reduce EMT/ECM marker expression and alleviate pulmonary fibrosis.
    Article Snippet: Ethnopharmacological relevance: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, irreversible interstitial lung disease that severely impairs patients’ quality of life and overall survival, yet few therapeutic drugs are available for this disease.. Cordyceps militaris (L.) Link. is an edible and medicinal fungus renowned for its lungand kidney-nourishing properties.. Decoctions containing C. militaris and other traditional Chinese medicines have been used clinically to treat elderly patients with IPF.

    other:

    Article Title: Andrographolide attenuates pulmonary fibrosis by covalently targeting Ptges3 and disrupting the Ptges3-Hsp90-NF-κB axis.
    Article Snippet: LPS and Pirfenidone were obtained from MedChem Express (USA).



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