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pafuramidine  (MedChemExpress)


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    Structured Review

    MedChemExpress pafuramidine
    Inhibition of CYP4F2-mediated metabolism of Compound- 3 . ( A ) Inhibition of Compound- 3 metabolism in HLM by various chemical inhibitors; ( B ) Inhibitory effect of Compound- 3 on the metabolism of <t>pafuramidine</t> (1.5 μM) mediated by CYP4F2 (10 nM); ( C ) Inhibitory effect of pafuramidine on the metabolism of Compound- 3 (1 μM) mediated by CYP4F2 (10 nM). Data were average values of three separate incubations.
    Pafuramidine, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 90/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pafuramidine/product/MedChemExpress
    Average 90 stars, based on 3 article reviews
    pafuramidine - by Bioz Stars, 2026-02
    90/100 stars

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    1) Product Images from "Involvement of CYP4F2 in the Metabolism of a Novel Monophosphate Ester Prodrug of Gemcitabine and Its Interaction Potential In Vitro"

    Article Title: Involvement of CYP4F2 in the Metabolism of a Novel Monophosphate Ester Prodrug of Gemcitabine and Its Interaction Potential In Vitro

    Journal: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry

    doi: 10.3390/molecules23051195

    Inhibition of CYP4F2-mediated metabolism of Compound- 3 . ( A ) Inhibition of Compound- 3 metabolism in HLM by various chemical inhibitors; ( B ) Inhibitory effect of Compound- 3 on the metabolism of pafuramidine (1.5 μM) mediated by CYP4F2 (10 nM); ( C ) Inhibitory effect of pafuramidine on the metabolism of Compound- 3 (1 μM) mediated by CYP4F2 (10 nM). Data were average values of three separate incubations.
    Figure Legend Snippet: Inhibition of CYP4F2-mediated metabolism of Compound- 3 . ( A ) Inhibition of Compound- 3 metabolism in HLM by various chemical inhibitors; ( B ) Inhibitory effect of Compound- 3 on the metabolism of pafuramidine (1.5 μM) mediated by CYP4F2 (10 nM); ( C ) Inhibitory effect of pafuramidine on the metabolism of Compound- 3 (1 μM) mediated by CYP4F2 (10 nM). Data were average values of three separate incubations.

    Techniques Used: Inhibition



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    MedChemExpress pafuramidine
    Inhibition of CYP4F2-mediated metabolism of Compound- 3 . ( A ) Inhibition of Compound- 3 metabolism in HLM by various chemical inhibitors; ( B ) Inhibitory effect of Compound- 3 on the metabolism of <t>pafuramidine</t> (1.5 μM) mediated by CYP4F2 (10 nM); ( C ) Inhibitory effect of pafuramidine on the metabolism of Compound- 3 (1 μM) mediated by CYP4F2 (10 nM). Data were average values of three separate incubations.
    Pafuramidine, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pafuramidine/product/MedChemExpress
    Average 90 stars, based on 1 article reviews
    pafuramidine - by Bioz Stars, 2026-02
    90/100 stars
      Buy from Supplier

    90
    Pohlig GmbH pafuramidine
    Inhibition of CYP4F2-mediated metabolism of Compound- 3 . ( A ) Inhibition of Compound- 3 metabolism in HLM by various chemical inhibitors; ( B ) Inhibitory effect of Compound- 3 on the metabolism of <t>pafuramidine</t> (1.5 μM) mediated by CYP4F2 (10 nM); ( C ) Inhibitory effect of pafuramidine on the metabolism of Compound- 3 (1 μM) mediated by CYP4F2 (10 nM). Data were average values of three separate incubations.
    Pafuramidine, supplied by Pohlig GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pafuramidine/product/Pohlig GmbH
    Average 90 stars, based on 1 article reviews
    pafuramidine - by Bioz Stars, 2026-02
    90/100 stars
      Buy from Supplier

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    Inhibition of CYP4F2-mediated metabolism of Compound- 3 . ( A ) Inhibition of Compound- 3 metabolism in HLM by various chemical inhibitors; ( B ) Inhibitory effect of Compound- 3 on the metabolism of pafuramidine (1.5 μM) mediated by CYP4F2 (10 nM); ( C ) Inhibitory effect of pafuramidine on the metabolism of Compound- 3 (1 μM) mediated by CYP4F2 (10 nM). Data were average values of three separate incubations.

    Journal: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry

    Article Title: Involvement of CYP4F2 in the Metabolism of a Novel Monophosphate Ester Prodrug of Gemcitabine and Its Interaction Potential In Vitro

    doi: 10.3390/molecules23051195

    Figure Lengend Snippet: Inhibition of CYP4F2-mediated metabolism of Compound- 3 . ( A ) Inhibition of Compound- 3 metabolism in HLM by various chemical inhibitors; ( B ) Inhibitory effect of Compound- 3 on the metabolism of pafuramidine (1.5 μM) mediated by CYP4F2 (10 nM); ( C ) Inhibitory effect of pafuramidine on the metabolism of Compound- 3 (1 μM) mediated by CYP4F2 (10 nM). Data were average values of three separate incubations.

    Article Snippet: Pafuramidine (purity ≥95%) was purchased from MedChemexpress (Monmouth Junction, NJ, USA).

    Techniques: Inhibition