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optineurin  (Proteintech)


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    Structured Review

    Proteintech optineurin
    Optineurin, supplied by Proteintech, used in various techniques. Bioz Stars score: 95/100, based on 144 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/optineurin/OPTN+Antibody/pm41776281-260-126-128
    Average 95 stars, based on 144 article reviews
    optineurin - by Bioz Stars, 2026-09
    95/100 stars

    Images

    Related Articles

    Membrane:

    Article Title: NSC228155 alleviates septic cardiomyopathy via protecting mitochondria and inhibiting inflammation.
    Article Snippet: Septic cardiomyopathy is a lethal symptom of sepsis.. Discovery of effective therapy that prevents cardiac injury in sepsis is critical in the clinical management of sepsis.. NSC228155 is a novel compound with therapeutic potential on acute kidney injury by preventing apoptosis and protecting mitochondria.

    Incubation:

    Article Title: Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration.
    Article Snippet: Lysates were centrifuged, and proteins in the supernatant were separated by NuPAGE® Precast Gel System (Thermofisher Scientific). .. Membranes were incubated with primary antibodies, including actin (#3700 S, Cell Signaling, 1:50000), ATG7 (MAB6608, R&D, 1:1000), ATG14 (PD026, MBL, 1:1000), dopamine transporter (MAB369, Millipore, 1:1000), ERK1/2 (#9107S, Cell Signaling, 1:1000), p-ERK1/2 (Thr202/Tyr204, #4370P, Cell Signaling, 1:1000), GFP/YFP (MA5-15256, Thermofisher Scientific, 1:2000), IκB (#4814, Cell Signaling, 1:1000), p-IRF3 (S396, #29047, Cell Signaling, 1:1000), IRF3 (#4302, Cell Signaling, 1:1000), JNK (#9252S, Cell Signaling, 1:1000), p-JNK (Thr183/Tyr185, #4671S, Cell Signaling, 1:1000), LC3B (#2775S, Cell Signaling, 1:1000), NBR1 (16004-1-AP, Proteintech, 1:1000), NDP52 (12229-1-AP, Proteintech, 1:1000), NQO-1 (11451-1-AP, Proteintech, 1:1000), HO-1 (sc-10789, Santa Cruz, 1:1000) p-NF-κB (S536, #3033S, Cell Signaling, 1:1000), Optineurin (10837-1-AP, Proteintech, 1:1000), p38 (#9212S, Cell Signaling, 1:1000), p-p38 (Thr180/Tyr182, #4511S, Cell Signaling, 1:1000), p62 (PM066, MBL, 1:50000), p62 (18420-1-AP, Proteintech, 1:1000), α-synuclein (clone MJFR1, ab138501, Abcam, 1:2000; clone 2f12, MABN1817, Millipore, 1:2000; clone 42, 610787 BD Bioscience, 1:1000; clone D37A6, # 4179, Cell Signaling, 1:1000), or Tyrosine hydroxylase (T2928, Sigma, 1:2000) at 4 °C overnight, washed with Tris-buffered saline containing 0.1% Tween 20, incubated with secondary antibodies, and visualized with SuperSignalTM West Pico Chemiluminescent Substrate (Thermofisher Scientific). ..

    Saline:

    Article Title: Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration.
    Article Snippet: Lysates were centrifuged, and proteins in the supernatant were separated by NuPAGE® Precast Gel System (Thermofisher Scientific). .. Membranes were incubated with primary antibodies, including actin (#3700 S, Cell Signaling, 1:50000), ATG7 (MAB6608, R&D, 1:1000), ATG14 (PD026, MBL, 1:1000), dopamine transporter (MAB369, Millipore, 1:1000), ERK1/2 (#9107S, Cell Signaling, 1:1000), p-ERK1/2 (Thr202/Tyr204, #4370P, Cell Signaling, 1:1000), GFP/YFP (MA5-15256, Thermofisher Scientific, 1:2000), IκB (#4814, Cell Signaling, 1:1000), p-IRF3 (S396, #29047, Cell Signaling, 1:1000), IRF3 (#4302, Cell Signaling, 1:1000), JNK (#9252S, Cell Signaling, 1:1000), p-JNK (Thr183/Tyr185, #4671S, Cell Signaling, 1:1000), LC3B (#2775S, Cell Signaling, 1:1000), NBR1 (16004-1-AP, Proteintech, 1:1000), NDP52 (12229-1-AP, Proteintech, 1:1000), NQO-1 (11451-1-AP, Proteintech, 1:1000), HO-1 (sc-10789, Santa Cruz, 1:1000) p-NF-κB (S536, #3033S, Cell Signaling, 1:1000), Optineurin (10837-1-AP, Proteintech, 1:1000), p38 (#9212S, Cell Signaling, 1:1000), p-p38 (Thr180/Tyr182, #4511S, Cell Signaling, 1:1000), p62 (PM066, MBL, 1:50000), p62 (18420-1-AP, Proteintech, 1:1000), α-synuclein (clone MJFR1, ab138501, Abcam, 1:2000; clone 2f12, MABN1817, Millipore, 1:2000; clone 42, 610787 BD Bioscience, 1:1000; clone D37A6, # 4179, Cell Signaling, 1:1000), or Tyrosine hydroxylase (T2928, Sigma, 1:2000) at 4 °C overnight, washed with Tris-buffered saline containing 0.1% Tween 20, incubated with secondary antibodies, and visualized with SuperSignalTM West Pico Chemiluminescent Substrate (Thermofisher Scientific). ..

    other:

    Article Title: Loganin alleviated cognitive impairment in 3×Tg-AD mice through promoting mitophagy mediated by optineurin.
    Article Snippet: Ethnopharmacological relevance: Corni Fructus is a traditional Chinese herb and widely applied for treatment of age-related disorders in China.. Iridoid glycoside was considered as the active ingredient of Corni Fructus.. Loganin is one of the major iridoid glycosides and quality control components of Corni Fructus.


    Western Blot:

    Article Title: Hypothermia promotes mitochondrial elongation In cardiac cells via inhibition of Drp1.
    Article Snippet: Hypothermia is a valuable clinical tool in mitigating against the consequences of ischemia in surgery, stroke, cardiac arrest and organ preservation.. Protection is afforded principally by a reduction of metabolism, manifesting as reduced rates of oxygen uptake, preservation of ATP levels, and a curtailing of ischemic calcium overload.. The effects of non-ischemic hypothermic stress are relatively unknown.



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