Review



t1777 pelitinib targetmol  (TargetMol)


Bioz Manufacturer Symbol TargetMol manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 94
      Buy from Supplier

    Structured Review

    TargetMol t1777 pelitinib targetmol
    T1777 Pelitinib Targetmol, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/t1777 pelitinib targetmol/product/TargetMol
    Average 94 stars, based on 4 article reviews
    t1777 pelitinib targetmol - by Bioz Stars, 2026-02
    94/100 stars

    Images



    Similar Products

    nintedanib  (MedChemExpress)
    95
    MedChemExpress nintedanib
    Nintedanib, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nintedanib/product/MedChemExpress
    Average 95 stars, based on 1 article reviews
    nintedanib - by Bioz Stars, 2026-02
    95/100 stars
    		  Buy from Supplier
    fda approved therapy nintedanib  (MedChemExpress)
    95
    MedChemExpress fda approved therapy nintedanib
    a-b: <t>Nintedanib</t> IC50 values from two IPF patients calculated by COL1A1 expression changes ( a ) and organoid surface area reduction ( b ). c-d: SB-431542 IC50 values with two IPF patients calculated by COL1A1 expression changes ( c ) and organoid surface area reduction ( d ). e-g : effect of Nintedanib (40nM, IC50 value for IPF1) on IPF1 secreted biomarkers: e . MMPs and TIMPs, f . TGFβ1 and TGFβ2, and g . chemokines and cytokines. h-j : effect of SB-431542 (60nM, IC50 value for IPF1) on IPF1 secreted biomarkers: h . MMPs and TIMPs, i . TGFβ1 and TGFβ2, and j . chemokines and cytokines. P values are calculated from technical replicates (n=3) for each biological replicate using one way ANOVA for each biomarker. ***: P<0.001, **: P<0.01, *: P<0.05.
    Fda Approved Therapy Nintedanib, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/fda approved therapy nintedanib/product/MedChemExpress
    Average 95 stars, based on 1 article reviews
    fda approved therapy nintedanib - by Bioz Stars, 2026-02
    95/100 stars
    		  Buy from Supplier
    drugs nintedanib  (MedChemExpress)
    95
    MedChemExpress drugs nintedanib
    a-b: <t>Nintedanib</t> IC50 values from two IPF patients calculated by COL1A1 expression changes ( a ) and organoid surface area reduction ( b ). c-d: SB-431542 IC50 values with two IPF patients calculated by COL1A1 expression changes ( c ) and organoid surface area reduction ( d ). e-g : effect of Nintedanib (40nM, IC50 value for IPF1) on IPF1 secreted biomarkers: e . MMPs and TIMPs, f . TGFβ1 and TGFβ2, and g . chemokines and cytokines. h-j : effect of SB-431542 (60nM, IC50 value for IPF1) on IPF1 secreted biomarkers: h . MMPs and TIMPs, i . TGFβ1 and TGFβ2, and j . chemokines and cytokines. P values are calculated from technical replicates (n=3) for each biological replicate using one way ANOVA for each biomarker. ***: P<0.001, **: P<0.01, *: P<0.05.
    Drugs Nintedanib, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/drugs nintedanib/product/MedChemExpress
    Average 95 stars, based on 1 article reviews
    drugs nintedanib - by Bioz Stars, 2026-02
    95/100 stars
    		  Buy from Supplier
    nintedanib nin  (MedChemExpress)
    95
    MedChemExpress nintedanib nin
    Structures of analyzed compounds: <t>nintedanib</t> <t>(NIN)</t> ( A ), BIBF 1202 ( B ) with fragmentations.
    Nintedanib Nin, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nintedanib nin/product/MedChemExpress
    Average 95 stars, based on 1 article reviews
    nintedanib nin - by Bioz Stars, 2026-02
    95/100 stars
    		  Buy from Supplier
    t1777 pelitinib targetmol  (TargetMol)
    94
    TargetMol t1777 pelitinib targetmol
    Structures of analyzed compounds: <t>nintedanib</t> <t>(NIN)</t> ( A ), BIBF 1202 ( B ) with fragmentations.
    T1777 Pelitinib Targetmol, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/t1777 pelitinib targetmol/product/TargetMol
    Average 94 stars, based on 1 article reviews
    t1777 pelitinib targetmol - by Bioz Stars, 2026-02
    94/100 stars
    		  Buy from Supplier
    t12282 nintedanib targetmol  (TargetMol)
    94
    TargetMol t12282 nintedanib targetmol
    Structures of analyzed compounds: <t>nintedanib</t> <t>(NIN)</t> ( A ), BIBF 1202 ( B ) with fragmentations.
    T12282 Nintedanib Targetmol, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/t12282 nintedanib targetmol/product/TargetMol
    Average 94 stars, based on 1 article reviews
    t12282 nintedanib targetmol - by Bioz Stars, 2026-02
    94/100 stars
    		  Buy from Supplier

    Image Search Results


    a-b: Nintedanib IC50 values from two IPF patients calculated by COL1A1 expression changes ( a ) and organoid surface area reduction ( b ). c-d: SB-431542 IC50 values with two IPF patients calculated by COL1A1 expression changes ( c ) and organoid surface area reduction ( d ). e-g : effect of Nintedanib (40nM, IC50 value for IPF1) on IPF1 secreted biomarkers: e . MMPs and TIMPs, f . TGFβ1 and TGFβ2, and g . chemokines and cytokines. h-j : effect of SB-431542 (60nM, IC50 value for IPF1) on IPF1 secreted biomarkers: h . MMPs and TIMPs, i . TGFβ1 and TGFβ2, and j . chemokines and cytokines. P values are calculated from technical replicates (n=3) for each biological replicate using one way ANOVA for each biomarker. ***: P<0.001, **: P<0.01, *: P<0.05.

    Journal: bioRxiv

    Article Title: Modeling cell-cell interactions to advance drug discovery in Idiopathic Pulmonary Fibrosis

    doi: 10.64898/2026.01.29.702646

    Figure Lengend Snippet: a-b: Nintedanib IC50 values from two IPF patients calculated by COL1A1 expression changes ( a ) and organoid surface area reduction ( b ). c-d: SB-431542 IC50 values with two IPF patients calculated by COL1A1 expression changes ( c ) and organoid surface area reduction ( d ). e-g : effect of Nintedanib (40nM, IC50 value for IPF1) on IPF1 secreted biomarkers: e . MMPs and TIMPs, f . TGFβ1 and TGFβ2, and g . chemokines and cytokines. h-j : effect of SB-431542 (60nM, IC50 value for IPF1) on IPF1 secreted biomarkers: h . MMPs and TIMPs, i . TGFβ1 and TGFβ2, and j . chemokines and cytokines. P values are calculated from technical replicates (n=3) for each biological replicate using one way ANOVA for each biomarker. ***: P<0.001, **: P<0.01, *: P<0.05.

    Article Snippet: To examine whether our IPF-Fib with iAT2 I73T/tdT cell co-culture organoid model will respond to the FDA approved therapy Nintedanib (Medchem Express, cat. BIBF 1120) and the TGFβ inhibitor SB-431542 (Alk5 inhibitor) (Medchem Express, cat. HY-10431), we tested these drugs in the organoid co-cultures using fibroblasts derived from two individual IPF patients in combination with the iAT2 I73T/tdT cells.

    Techniques: Expressing, Biomarker Discovery

    a-b: Nintedanib IC50 values from two IPF patients calculated by COL1A1 expression changes ( a ) and organoid surface area reduction ( b ). c-d: SB-431542 IC50 values with two IPF patients calculated by COL1A1 expression changes ( c ) and organoid surface area reduction ( d ). e-g : effect of Nintedanib (40nM, IC50 value for IPF1) on IPF1 secreted biomarkers: e . MMPs and TIMPs, f . TGFβ1 and TGFβ2, and g . chemokines and cytokines. h-j : effect of SB-431542 (60nM, IC50 value for IPF1) on IPF1 secreted biomarkers: h . MMPs and TIMPs, i . TGFβ1 and TGFβ2, and j . chemokines and cytokines. P values are calculated from technical replicates (n=3) for each biological replicate using one way ANOVA for each biomarker. ***: P<0.001, **: P<0.01, *: P<0.05.

    Journal: bioRxiv

    Article Title: Modeling cell-cell interactions to advance drug discovery in Idiopathic Pulmonary Fibrosis

    doi: 10.64898/2026.01.29.702646

    Figure Lengend Snippet: a-b: Nintedanib IC50 values from two IPF patients calculated by COL1A1 expression changes ( a ) and organoid surface area reduction ( b ). c-d: SB-431542 IC50 values with two IPF patients calculated by COL1A1 expression changes ( c ) and organoid surface area reduction ( d ). e-g : effect of Nintedanib (40nM, IC50 value for IPF1) on IPF1 secreted biomarkers: e . MMPs and TIMPs, f . TGFβ1 and TGFβ2, and g . chemokines and cytokines. h-j : effect of SB-431542 (60nM, IC50 value for IPF1) on IPF1 secreted biomarkers: h . MMPs and TIMPs, i . TGFβ1 and TGFβ2, and j . chemokines and cytokines. P values are calculated from technical replicates (n=3) for each biological replicate using one way ANOVA for each biomarker. ***: P<0.001, **: P<0.01, *: P<0.05.

    Article Snippet: The drugs Nintedanib (Medchem Express, cat. BIBF 1120) and SB-431542 (Medchem Express, cat. HY-10431) were received as powders and diluted in DMSO to a stock concentration of 10 mM.

    Techniques: Expressing, Biomarker Discovery

    Structures of analyzed compounds: nintedanib (NIN) ( A ), BIBF 1202 ( B ) with fragmentations.

    Journal: Pharmaceutics

    Article Title: Development and Validation of LC-MS/MS Method for Nintedanib and BIBF 1202 Monitoring in Plasma of Patients with Progressive Pulmonary Fibrosis Associated with Systemic Sclerosis

    doi: 10.3390/pharmaceutics17121553

    Figure Lengend Snippet: Structures of analyzed compounds: nintedanib (NIN) ( A ), BIBF 1202 ( B ) with fragmentations.

    Article Snippet: Nintedanib (NIN) and BIBF 1202 reference standards were obtained from MedChemExpress (Monmouth Junction, NJ, USA).

    Techniques: