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Alomone Labs nbqx
Nbqx, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 95/100, based on 54 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/nbqx/NBQX/pmc13628563-80-0-4
Average 95 stars, based on 54 article reviews

nbqx - by Bioz Stars, 2026-11

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Article Title: Oxytocin Improves Autistic Behaviors by Positively Shifting GABA Reversal Potential via NKCC1 in Early-Postnatal-Stage.
Article Snippet: The membranes were incubated with an anti-rabbit/mouse IgG secondary antibody diluted at 1:2000 (Millipore) for 1 h, followed by enhanced chemiluminescence detection of the proteins with enhanced chemiluminescence (ECL) (Vazyme, Nanjing, CN).

Article Title: Crosstalk of noradrenergic Ca 2+ and cAMP signaling in astrocytes of the murine olfactory bulb
Article Snippet: The following drugs were used: (R)-(-)-Phenylephrine hydrochloride (3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol; hydrochloride; Abcam, Cambridge, United Kingdom), 2-APB (2-diphenylboranyloxyethanamine; Calbiochem, Darmstadt, Germany), BMY7378 (8-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-8-azaspiro[4.5]decane-7,9-dione; dihydrochloride; Hello Bio, Bristol, United Kingdom), CGP 55,845 hydrochloride (benzyl-[(2 S)-3-[[(1 S)-1-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropyl]phosphinic acid; hydrochloride; Hello Bio), Cyclopiazonic acid ((2R,3 S,9R)-5-acetyl-4-hydroxy-8,8-dimethyl-7,16-diazapentacyclo[9.6.1.02,9.03,7.015,18]octadeca-1(17),4,11(18),12,14-pentaen-6-one; Hello Bio), D-AP5 ((2R)-2-amino-5-phosphonopentanoic acid; Alomone Labs, Jerusalem, Israel), Norepinephrine bitartrate (4-[(1 R )-2-amino-1-hydroxyethyl]benzene-1,2-diol;2,3-dihydroxybutanedioic acid; Merck KGaA, Darmstadt, Germany), Forskolin ([(3R,4aR,5 S,6 S,6aS,10 S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2 H-benzo[f]chromen-5-yl] acetate; Cayman Chemical, Ann Arbor, Michigan, USA), Gabazine (4-[6-imino-3-(4-methoxyphenyl)pyridazin-1-yl]butanoic acid; Abcam), HC-067047 (2-methyl-1-(3-morpholin-4-ylpropyl)-5-phenyl-N-[3-(trifluoromethyl)phenyl]pyrrole-3-carboxamide; Calbiochem), ICI 118,551 hydrochloride ((2R,3 S)-1-[(7-methyl-2,3-dihydro-1 H-inden-4-yl)oxy]-3-(propan-2-ylamino)butan-2-ol; hydrochloride; Tocris Bioscience, Bristol, United Kingdom), Isoprenaline hydrochloride (4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol; hydrochloride; Abcam), NBQX (disodium;6-nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-diolate; Alomone Labs), NKY80 (2-amino-7-(furan-2-yl)-7,8-dihydro-6 H-quinazolin-5-one; Tocris Bioscience), Prazosin hydrochloride ([4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone; hydrochloride; Tocris Bioscience), Rauwolscine hydrochloride (methyl (1 S,15 S,18 S,19 S,20 S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate; hydrochloride; Tocris Bioscience), RS100329 hydochloride (5-methyl-3-[3-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-1 H-pyrimidine-2,4-dione; hydrochloride; Tocris Bioscience), ST 034307 (6-chloro-2-(trichloromethyl)chromen-4-one; Tocris Bioscience), tetrodotoxin citrate ((1R,5R,6R,7R,9 S,11 S,12 S,13 S,14 S)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.17,11.01,6]tetradec-3-ene-5,9,12,13,14-pentol; Hello Bio), Xylazine (N-(2,6-dimethylphenyl)-5,6-dihydro-4 H-1,3-thiazin-2-amine; hydrochloride; Merck).

Article Title: Crosstalk of noradrenergic Ca 2+ and cAMP signaling in astrocytes of the murine olfactory bulb
Article Snippet: The following drugs were used: (R)-(−)-Phenylephrine hydrochloride (3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol;hydrochloride; Abcam, Cambridge, United Kingdom), 2-APB (2-diphenylboranyloxyethanamine; Calbiochem, Darmstadt, Germany), BMY7378 (8-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-8-azaspiro[4.5]decane-7,9-dione;dihydrochloride; Hello Bio, Bristol, United Kingdom), CGP 55845 hydrochloride (benzyl-[(2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropyl]phosphinic acid; hydrochloride; Hello Bio), Cyclopiazonic acid ((2R,3S,9R)-5-acetyl-4-hydroxy-8,8-dimethyl-7,16-diazapentacyclo[9.6.1.02,9.03,7.015,18]octadeca-1(17),4,11(18),12,14-pentaen-6-one; Hello Bio), D-AP5 ((2R)-2-amino-5-phosphonopentanoic acid; Alomone Labs, Jerusalem, Israel), Norepinephrine bitartrate (4-[(1 R )-2-amino-1-hydroxyethyl]benzene-1,2-diol;2,3-dihydroxybutanedioic acid; Merck KGaA, Darmstadt, Germany), Forskolin ([(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate; Cayman Chemical, Ann Arbor, Michigan, USA), Gabazine (4-[6-imino-3-(4-methoxyphenyl)pyridazin-1-yl]butanoic acid; Abcam), HC-067047 (2-methyl-1-(3-morpholin-4-ylpropyl)-5-phenyl-N-[3-(trifluoromethyl)phenyl]pyrrole-3-carboxamide; Calbiochem), ICI 118,551 hydrochloride ((2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-(propan-2-ylamino)butan-2-ol;hydrochloride; Tocris Bioscience, Bristol, United Kingdom), Isoprenaline hydrochloride (4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol;hydrochloride; Abcam), NBQX (disodium;6-nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-diolate; Alomone Labs), NKY80 (2-amino-7-(furan-2-yl)-7,8-dihydro-6H-quinazolin-5-one; Tocris Bioscience), Prazosin hydrochloride ([4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone;hydrochloride; Tocris Bioscience), Rauwolscine hydrochloride (methyl (1S,15S,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;hydrochloride; Tocris Bioscience), RS100329 hydochloride (5-methyl-3-[3-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]-1H-pyrimidine-2,4-dione;hydrochloride; Tocris Bioscience), ST 034307 (6-chloro-2-(trichloromethyl)chromen-4-one; Tocris Bioscience), tetrodotoxin citrate ((1R,5R,6R,7R,9S,11S,12S,13S,14S)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.17,11.01,6]tetradec-3-ene-5,9,12,13,14-pentol; Hello Bio), Xylazine (N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine;hydrochloride; Merck).

Article Title: Crosstalk of noradrenergic Ca 2+ and cAMP signaling in astrocytes of the murine olfactory bulb.
Article Snippet: The following drugs were used: (R)-(-)-Phenylephrine hydrochloride (3-[(1R)-1-hydroxy-2-(methylamino) ethyl]phenol; hydrochloride; Abcam, Cambridge, United Kingdom), 2-APB (2-diphenylboranyloxyethanamine; Calbiochem, Darmstadt, Germany), BMY7378 (8-[2-[4-(2-methoxyphenyl)piperazin-1-yl] ethyl]-8-azaspiro[4.5]decane-7,9-dione; dihydrochloride; Hello Bio, Bristol, United Kingdom), CGP 55,845 hydrochloride (benzyl-[(2 S)-3-[[(1 S)-1-(3,4-dichlorophenyl )e thyl ]amino]-2-hydroxy propyl ]phos - phinic acid; hydrochloride; Hello Bio), Cyclopiazonic acid ((2R,3 S,9R)-5-acetyl-4-hydroxy-8,8-dimethyl7,16-diazapentacyclo[9.6.1.02,9.03,7.015,18]octadeca-1(17),4,11(18),12,14-pentaen-6-one; Hello Bio), D-AP5 ((2R)-2-amino-5-phosphonopentanoic acid; Alomone Labs, Jerusalem, Israel), Norepinephrine bitartrate (4-[(1R)-2-amino-1-hydroxyethyl] benzene-1,2-diol;2,3-dihydroxybutanedioic acid; Merck KGaA, Darmstadt, Germany), Forskolin ([(3R,4aR,5 S,6 S,6aS,10 S,10aR,10bS)-3-ethenyl6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo5,6,6a,8,9,10-hexahydro-2 H-benzo[f ] chromen-5-yl] acetate; Cayman Chemical, Ann Arbor, Michigan, USA), Gabazine (4-[6-imino-3-(4methoxyphenyl)pyridazin-1-yl]butanoic acid; Abcam), HC-067047 (2-methyl-1-(3-morpholin-4-ylpropyl)-5phenyl-N-[3-(trifluoromethyl)phenyl]pyrrole-3-carboxamide; Calbiochem), ICI 118,551 hydrochloride ((2R,3 S)-1-[(7-methyl-2,3-dihydro-1 H-inden-4-yl)oxy]3-(propan-2-ylamino)butan-2-ol; hydrochloride; Tocris Bioscience, Bristol, United Kingdom), Isoprenaline hydrochloride (4-[1-hydroxy-2-(propan-2-ylamino) ethyl]benzene-1,2-diol; hydrochloride; Abcam), NBQX (disodium;6-nitro-7-sulfamoylbenzo[f ]quinoxaline2,3-diolate; Alomone Labs), NKY80 (2-amino-7(furan-2-yl)-7,8-dihydro-6 H-quinazolin-5-one; Tocris Bioscience), Prazosin hydrochloride ([4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl) methanone; hydrochloride; Tocris Bioscience), Rauwolscine hydrochloride (methyl (1 S,15 S,18 S,19 S,20 S)18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate; hydrochloride; Tocris Bioscience), RS100329 hydochloride (5-methyl3-[3-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl] propyl]-1 H-pyrimidine-2,4-dione; hydrochloride; Tocris Bioscience), ST 034307 (6-chloro-2-(trichloromethyl) chromen-4-one; Tocris Bioscience), tetrodotoxin citrate ((1R,5R,6R,7R,9 S,11 S,12 S,13 S,14 S)-3-amino14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.17,11.01,6]tetradec-3-ene-5,9,12,13,14-pentol; Hello Bio), Xylazine (N-(2,6-dimethylphenyl)-5,6-dihydro-4 H-1,3-thiazin-2-amine; hydrochloride; Merck).

Transferring:

Article Title: Oxytocin Improves Autistic Behaviors by Positively Shifting GABA Reversal Potential via NKCC1 in Early‐Postnatal‐Stage
Article Snippet: .. The sGABA‐PSCs and mGABA‐PSCs were recorded at a holding potential of −70 mV using high Cl − pipette solution in the presence of D‐APV (50 μ m ; Tocris Bioscience, Bristol, UK, cat. number: No. 0106/1) and NBQX (20 μ m ; Tocris Bioscience, Bristol, UK, cat. number: No. 0373/10), with or without TTX (0.3 μ m ; Alomone Labs, Israel, cat. number: 18660‐81‐6), respectively. .. Moreover, the sGlut‐PSCs and mGlut‐PSCs were recorded at a holding potential of −70 mV using a Cs + ‐methanesulfonate‐based internal solution in the presence of SR95531 (20 μ m ; Tocris Bioscience, cat. number: No. 1262/10), with or without TTX (0.3 μ m ), respectively.

Saline:

Article Title: Repeated administration of AMPA/kainate antagonists transiently suppresses nicotine-seeking in an operant rat model.
Article Snippet: .. NBQX was purchased from Alomone Labs (Jerusalem, Israel) and dissolved in saline to obtain 5 mg/ml concentration. ..

Concentration Assay:

Transfection:

Article Title: A De Novo Arg649Trp Variant in GluA2 Impairs Its Assembly With GluA1: Associated With Epilepsy and Neurodevelopmental Disorders
Article Snippet: When the cell confluence reached 50% –60%, the plasmid vectors were transfected into the cells using Lipofectamine 2000 reagent (ThermoFisher Scientific). .. NBQX (100 μ M, Alomone Labs, Jerusalem, Israel) was included in the culture medium after transfection to prohibit the cytotoxicity of AMPARs. ..

Review