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aquabluer multitarget pharmaceuticals  (TargetMol)


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    TargetMol aquabluer multitarget pharmaceuticals
    Aquabluer Multitarget Pharmaceuticals, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 33 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/multitarget/Multi-Target+Compound+Library/pm41349546-971-147-160
    Average 94 stars, based on 33 article reviews
    aquabluer multitarget pharmaceuticals - by Bioz Stars, 2026-09
    94/100 stars

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    Related Articles

    Recombinant:

    Article Title: A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals, peptides, and recombinant proteins Tamoxifen (TAM) Sigma T5648; CAS: 10540-29-1 Normal Goat Serum Cell Signaling 5425 Dulbecco’s modified Eagle’s medium (DMEM), high glucose, pyruvate, no glutamine Gibco 21969035 Fetal bovine serum (FBS) Gibco 2177353 Trolox Thermo Scientific Acros 10782831; CAS: 53188-07-1 Liproxstatin-1 (Lip-1) Selleckchem S7699; CAS: 950455-15-9 4-hydroxytamoxifen (4-hydroxy-TAM) Sigma-Aldrich SIALH7904; CAS: 68047-06-3 StemMACS iPS-Brew medium Miltenyi Biotec 130-104-368 StemMACS Passaging Solution XF Miltenyi Biotec 130-104-688 Y-27632 dihydrochloride Tocris 1254; CAS: 129830-38-2 Insulin solution human recombinant Sigma-Aldrich I9278 LDN TargetMol Chemicals Inc. 001594962; CAS: 1062368-24-4 StemMACS SB431542 in Solution Miltenyi Biotec 130-106-543 Mouse Laminin Sigma Aldrich SIALL2020; CAS: 114956-81-9 FGF2 Miltenyi Biotec 130-093-838 Human BDNF Miltenyi Biotec 130-093-811 StemMACs iPS-Brew XF Miltenyi Biotec 130-104-368 Accutase Gibco A1110501 Y-27632 Miltenyi Biotec 130-103-922 SB-431542 Hycultec HY-10431 XAV939 Tocris 3748 B27-AO Thermo Fisher Scientific 10889038 Neg-50 Epredia 6502B PEI MAX® Polysciences Europe GmbH 24765-100 AquaBluer MultiTarget Pharmaceuticals, LLC 6015 BODIPYTM 581/591 C11 Invitrogen D3861 RSL3 1S (RSL3) TargetMol Chemicals Inc. T3646; CAS: 1219810-16-8 L-glutathione reduced (GSH) Sigma Aldrich G6013; CAS: 70-18-8 NADPH/H + Roche 10107824001 Glutathione Reductase from baker’s yeast (S. cerevisiae) Sigma Aldrich G3664; CAS: 9001-48-3 Phosphatidylcholine hydroperoxide (PCOOH) gift from Junya Ito, Tohoku University, Sendai, Japan N/A Collagenase A Roche 10103578001; CAS: 9001-12-1 Percoll® Density Gradient Media Sigma Aldrich 17-0891-01 SPLASH® LIPIDOMIX® Avanti 330707 Alexa FluorTM 488 C5 Maleimide Invitrogen A10254 Dil Stain (1,1’-Dioctadecyl-3,3,3’,3’Tetramethylindocarbocyanine Perchlorate (’DiI’; DiIC18(3))) Invitrogen D282 1,2-Diheptanoyl-sn-glycero-3phosphocholine (D7PC) Avanti Polar Lipids (Alabaster, USA) 100124-676; CAS: 39036-04-9 1,2-Dimyristoyl-sn-glycero-3phosphocholine (DMPC) Avanti Polar Lipids (Alabaster, USA) O-1135.0001BA; CAS: 18194-24-6 IGEPAL® CA-630 Sigma Aldrich I8896; CAS: 9002-93-1 Tissue-Tek® mounting medium Tissue-Tek® O.C.T. ..

    Modification:

    Article Title: A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals, peptides, and recombinant proteins Tamoxifen (TAM) Sigma T5648; CAS: 10540-29-1 Normal Goat Serum Cell Signaling 5425 Dulbecco’s modified Eagle’s medium (DMEM), high glucose, pyruvate, no glutamine Gibco 21969035 Fetal bovine serum (FBS) Gibco 2177353 Trolox Thermo Scientific Acros 10782831; CAS: 53188-07-1 Liproxstatin-1 (Lip-1) Selleckchem S7699; CAS: 950455-15-9 4-hydroxytamoxifen (4-hydroxy-TAM) Sigma-Aldrich SIALH7904; CAS: 68047-06-3 StemMACS iPS-Brew medium Miltenyi Biotec 130-104-368 StemMACS Passaging Solution XF Miltenyi Biotec 130-104-688 Y-27632 dihydrochloride Tocris 1254; CAS: 129830-38-2 Insulin solution human recombinant Sigma-Aldrich I9278 LDN TargetMol Chemicals Inc. 001594962; CAS: 1062368-24-4 StemMACS SB431542 in Solution Miltenyi Biotec 130-106-543 Mouse Laminin Sigma Aldrich SIALL2020; CAS: 114956-81-9 FGF2 Miltenyi Biotec 130-093-838 Human BDNF Miltenyi Biotec 130-093-811 StemMACs iPS-Brew XF Miltenyi Biotec 130-104-368 Accutase Gibco A1110501 Y-27632 Miltenyi Biotec 130-103-922 SB-431542 Hycultec HY-10431 XAV939 Tocris 3748 B27-AO Thermo Fisher Scientific 10889038 Neg-50 Epredia 6502B PEI MAX® Polysciences Europe GmbH 24765-100 AquaBluer MultiTarget Pharmaceuticals, LLC 6015 BODIPYTM 581/591 C11 Invitrogen D3861 RSL3 1S (RSL3) TargetMol Chemicals Inc. T3646; CAS: 1219810-16-8 L-glutathione reduced (GSH) Sigma Aldrich G6013; CAS: 70-18-8 NADPH/H + Roche 10107824001 Glutathione Reductase from baker’s yeast (S. cerevisiae) Sigma Aldrich G3664; CAS: 9001-48-3 Phosphatidylcholine hydroperoxide (PCOOH) gift from Junya Ito, Tohoku University, Sendai, Japan N/A Collagenase A Roche 10103578001; CAS: 9001-12-1 Percoll® Density Gradient Media Sigma Aldrich 17-0891-01 SPLASH® LIPIDOMIX® Avanti 330707 Alexa FluorTM 488 C5 Maleimide Invitrogen A10254 Dil Stain (1,1’-Dioctadecyl-3,3,3’,3’Tetramethylindocarbocyanine Perchlorate (’DiI’; DiIC18(3))) Invitrogen D282 1,2-Diheptanoyl-sn-glycero-3phosphocholine (D7PC) Avanti Polar Lipids (Alabaster, USA) 100124-676; CAS: 39036-04-9 1,2-Dimyristoyl-sn-glycero-3phosphocholine (DMPC) Avanti Polar Lipids (Alabaster, USA) O-1135.0001BA; CAS: 18194-24-6 IGEPAL® CA-630 Sigma Aldrich I8896; CAS: 9002-93-1 Tissue-Tek® mounting medium Tissue-Tek® O.C.T. ..

    Passaging:

    Article Title: A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals, peptides, and recombinant proteins Tamoxifen (TAM) Sigma T5648; CAS: 10540-29-1 Normal Goat Serum Cell Signaling 5425 Dulbecco’s modified Eagle’s medium (DMEM), high glucose, pyruvate, no glutamine Gibco 21969035 Fetal bovine serum (FBS) Gibco 2177353 Trolox Thermo Scientific Acros 10782831; CAS: 53188-07-1 Liproxstatin-1 (Lip-1) Selleckchem S7699; CAS: 950455-15-9 4-hydroxytamoxifen (4-hydroxy-TAM) Sigma-Aldrich SIALH7904; CAS: 68047-06-3 StemMACS iPS-Brew medium Miltenyi Biotec 130-104-368 StemMACS Passaging Solution XF Miltenyi Biotec 130-104-688 Y-27632 dihydrochloride Tocris 1254; CAS: 129830-38-2 Insulin solution human recombinant Sigma-Aldrich I9278 LDN TargetMol Chemicals Inc. 001594962; CAS: 1062368-24-4 StemMACS SB431542 in Solution Miltenyi Biotec 130-106-543 Mouse Laminin Sigma Aldrich SIALL2020; CAS: 114956-81-9 FGF2 Miltenyi Biotec 130-093-838 Human BDNF Miltenyi Biotec 130-093-811 StemMACs iPS-Brew XF Miltenyi Biotec 130-104-368 Accutase Gibco A1110501 Y-27632 Miltenyi Biotec 130-103-922 SB-431542 Hycultec HY-10431 XAV939 Tocris 3748 B27-AO Thermo Fisher Scientific 10889038 Neg-50 Epredia 6502B PEI MAX® Polysciences Europe GmbH 24765-100 AquaBluer MultiTarget Pharmaceuticals, LLC 6015 BODIPYTM 581/591 C11 Invitrogen D3861 RSL3 1S (RSL3) TargetMol Chemicals Inc. T3646; CAS: 1219810-16-8 L-glutathione reduced (GSH) Sigma Aldrich G6013; CAS: 70-18-8 NADPH/H + Roche 10107824001 Glutathione Reductase from baker’s yeast (S. cerevisiae) Sigma Aldrich G3664; CAS: 9001-48-3 Phosphatidylcholine hydroperoxide (PCOOH) gift from Junya Ito, Tohoku University, Sendai, Japan N/A Collagenase A Roche 10103578001; CAS: 9001-12-1 Percoll® Density Gradient Media Sigma Aldrich 17-0891-01 SPLASH® LIPIDOMIX® Avanti 330707 Alexa FluorTM 488 C5 Maleimide Invitrogen A10254 Dil Stain (1,1’-Dioctadecyl-3,3,3’,3’Tetramethylindocarbocyanine Perchlorate (’DiI’; DiIC18(3))) Invitrogen D282 1,2-Diheptanoyl-sn-glycero-3phosphocholine (D7PC) Avanti Polar Lipids (Alabaster, USA) 100124-676; CAS: 39036-04-9 1,2-Dimyristoyl-sn-glycero-3phosphocholine (DMPC) Avanti Polar Lipids (Alabaster, USA) O-1135.0001BA; CAS: 18194-24-6 IGEPAL® CA-630 Sigma Aldrich I8896; CAS: 9002-93-1 Tissue-Tek® mounting medium Tissue-Tek® O.C.T. ..

    Staining:

    Article Title: A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals, peptides, and recombinant proteins Tamoxifen (TAM) Sigma T5648; CAS: 10540-29-1 Normal Goat Serum Cell Signaling 5425 Dulbecco’s modified Eagle’s medium (DMEM), high glucose, pyruvate, no glutamine Gibco 21969035 Fetal bovine serum (FBS) Gibco 2177353 Trolox Thermo Scientific Acros 10782831; CAS: 53188-07-1 Liproxstatin-1 (Lip-1) Selleckchem S7699; CAS: 950455-15-9 4-hydroxytamoxifen (4-hydroxy-TAM) Sigma-Aldrich SIALH7904; CAS: 68047-06-3 StemMACS iPS-Brew medium Miltenyi Biotec 130-104-368 StemMACS Passaging Solution XF Miltenyi Biotec 130-104-688 Y-27632 dihydrochloride Tocris 1254; CAS: 129830-38-2 Insulin solution human recombinant Sigma-Aldrich I9278 LDN TargetMol Chemicals Inc. 001594962; CAS: 1062368-24-4 StemMACS SB431542 in Solution Miltenyi Biotec 130-106-543 Mouse Laminin Sigma Aldrich SIALL2020; CAS: 114956-81-9 FGF2 Miltenyi Biotec 130-093-838 Human BDNF Miltenyi Biotec 130-093-811 StemMACs iPS-Brew XF Miltenyi Biotec 130-104-368 Accutase Gibco A1110501 Y-27632 Miltenyi Biotec 130-103-922 SB-431542 Hycultec HY-10431 XAV939 Tocris 3748 B27-AO Thermo Fisher Scientific 10889038 Neg-50 Epredia 6502B PEI MAX® Polysciences Europe GmbH 24765-100 AquaBluer MultiTarget Pharmaceuticals, LLC 6015 BODIPYTM 581/591 C11 Invitrogen D3861 RSL3 1S (RSL3) TargetMol Chemicals Inc. T3646; CAS: 1219810-16-8 L-glutathione reduced (GSH) Sigma Aldrich G6013; CAS: 70-18-8 NADPH/H + Roche 10107824001 Glutathione Reductase from baker’s yeast (S. cerevisiae) Sigma Aldrich G3664; CAS: 9001-48-3 Phosphatidylcholine hydroperoxide (PCOOH) gift from Junya Ito, Tohoku University, Sendai, Japan N/A Collagenase A Roche 10103578001; CAS: 9001-12-1 Percoll® Density Gradient Media Sigma Aldrich 17-0891-01 SPLASH® LIPIDOMIX® Avanti 330707 Alexa FluorTM 488 C5 Maleimide Invitrogen A10254 Dil Stain (1,1’-Dioctadecyl-3,3,3’,3’Tetramethylindocarbocyanine Perchlorate (’DiI’; DiIC18(3))) Invitrogen D282 1,2-Diheptanoyl-sn-glycero-3phosphocholine (D7PC) Avanti Polar Lipids (Alabaster, USA) 100124-676; CAS: 39036-04-9 1,2-Dimyristoyl-sn-glycero-3phosphocholine (DMPC) Avanti Polar Lipids (Alabaster, USA) O-1135.0001BA; CAS: 18194-24-6 IGEPAL® CA-630 Sigma Aldrich I8896; CAS: 9002-93-1 Tissue-Tek® mounting medium Tissue-Tek® O.C.T. ..



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    Image Search Results


    Network diagrams of comparisons on different treatments. Direct comparisons are represented by the colored lines connecting the treatments. Line width is proportional to the number of trials, including every pair of treatments, whereas circle size is proportional to the total number of patients for each treatment in the network. Adeb, Adebrelimab; Atez, Atezolizumab; Atez-beva, Atezolizumab + bevacizumab; Benm + anlo, Benmelstobart + anlotinib; Durv, Durvalumab; Nivo, Nivolumab; Pemb, Pembrolizumab; Pla, placebo; Serp, Serplulimab; Tira + atez, Tiragolumabz + atezolizumab; Tisl, Tislelizumab; Tori, Toripalimab.

    Journal: Therapeutic Advances in Medical Oncology

    Article Title: Efficacy and safety of first-line PD-1/PD-L1 inhibitors combined with or without anti-angiogenesis therapy for extensive-stage small-cell lung cancer: a network meta-analysis

    doi: 10.1177/17588359251348310

    Figure Lengend Snippet: Network diagrams of comparisons on different treatments. Direct comparisons are represented by the colored lines connecting the treatments. Line width is proportional to the number of trials, including every pair of treatments, whereas circle size is proportional to the total number of patients for each treatment in the network. Adeb, Adebrelimab; Atez, Atezolizumab; Atez-beva, Atezolizumab + bevacizumab; Benm + anlo, Benmelstobart + anlotinib; Durv, Durvalumab; Nivo, Nivolumab; Pemb, Pembrolizumab; Pla, placebo; Serp, Serplulimab; Tira + atez, Tiragolumabz + atezolizumab; Tisl, Tislelizumab; Tori, Toripalimab.

    Article Snippet: A small-molecule and a multitarget TKI, Anlotinib, has indicated an increased OS of 2.4 months when applied as a later-line therapy for ES-SCLC patients compared to placebo., Therefore, NMPA has recommended anlotinib as a third-line or subsequent-line treatment option for ES-SCLC patients.

    Techniques:

    HRs, ORs, and their 95% confidence intervals from network meta-analysis of different first-line therapeutic regimens in ES-SCLC patients. (a) HRs and 95% CI for overall survival (upper triangle in yellow) and progression-free survival (lower triangle in green). The hazard ratio < 1.00 provides better survival benefits. (b) ORs and 95% CI for objective response rate (upper triangle in yellow) and grade ⩾ 3 adverse events (lower triangle in green). OR < 1.00 indicates a better efficacy or more toxicity. The results are presented as column-defined treatment versus row-defined treatment. Significant results are in bold. Adeb, Adebrelimab; Atez, Atezolizumab; Atez-beva, Atezolizumab + bevacizumab; Benm-anlo, Benmelstobart + anlotinib; Chemo, Chemotherapy; CI, confidence intervals; Durv, Durvalumab; ES-SCLC, extensive-stage small-cell lung cancer; HR, hazard ratios; Nivo, Nivolumab; OR, odds ratio; Pemb, Pembrolizumab; Serp, Serplulimab; Tisl, Tislelizumab; Tori, Toripalimab.

    Journal: Therapeutic Advances in Medical Oncology

    Article Title: Efficacy and safety of first-line PD-1/PD-L1 inhibitors combined with or without anti-angiogenesis therapy for extensive-stage small-cell lung cancer: a network meta-analysis

    doi: 10.1177/17588359251348310

    Figure Lengend Snippet: HRs, ORs, and their 95% confidence intervals from network meta-analysis of different first-line therapeutic regimens in ES-SCLC patients. (a) HRs and 95% CI for overall survival (upper triangle in yellow) and progression-free survival (lower triangle in green). The hazard ratio < 1.00 provides better survival benefits. (b) ORs and 95% CI for objective response rate (upper triangle in yellow) and grade ⩾ 3 adverse events (lower triangle in green). OR < 1.00 indicates a better efficacy or more toxicity. The results are presented as column-defined treatment versus row-defined treatment. Significant results are in bold. Adeb, Adebrelimab; Atez, Atezolizumab; Atez-beva, Atezolizumab + bevacizumab; Benm-anlo, Benmelstobart + anlotinib; Chemo, Chemotherapy; CI, confidence intervals; Durv, Durvalumab; ES-SCLC, extensive-stage small-cell lung cancer; HR, hazard ratios; Nivo, Nivolumab; OR, odds ratio; Pemb, Pembrolizumab; Serp, Serplulimab; Tisl, Tislelizumab; Tori, Toripalimab.

    Article Snippet: A small-molecule and a multitarget TKI, Anlotinib, has indicated an increased OS of 2.4 months when applied as a later-line therapy for ES-SCLC patients compared to placebo., Therefore, NMPA has recommended anlotinib as a third-line or subsequent-line treatment option for ES-SCLC patients.

    Techniques:

    Bayesian ranking profiles of comparable treatments on efficacy and safety for ES-SCLC patients. Ranking plots indicate the probability of each comparable immunotherapy combination being ranked from first to last on OS, PFS, ORR, and grade ⩾ 3 AEs. Adeb, Adebrelimab; AE, adverse event; Atez, Atezolizumab; Atez-beva, Atezolizumab + bevacizumab; Benm-anlo, Benmelstobart + anlotinib; Durv, Durvalumab; ES-SCLC, extensive-stage small-cell lung cancer; Nivo, Nivolumab; ORR, overall response rate; OS, overall survival; Pemb, Pembrolizumab; PFS, progression-free survival; Serp, Serplulimab; Tisl, Tislelizumab; Tori, Toripalimab.

    Journal: Therapeutic Advances in Medical Oncology

    Article Title: Efficacy and safety of first-line PD-1/PD-L1 inhibitors combined with or without anti-angiogenesis therapy for extensive-stage small-cell lung cancer: a network meta-analysis

    doi: 10.1177/17588359251348310

    Figure Lengend Snippet: Bayesian ranking profiles of comparable treatments on efficacy and safety for ES-SCLC patients. Ranking plots indicate the probability of each comparable immunotherapy combination being ranked from first to last on OS, PFS, ORR, and grade ⩾ 3 AEs. Adeb, Adebrelimab; AE, adverse event; Atez, Atezolizumab; Atez-beva, Atezolizumab + bevacizumab; Benm-anlo, Benmelstobart + anlotinib; Durv, Durvalumab; ES-SCLC, extensive-stage small-cell lung cancer; Nivo, Nivolumab; ORR, overall response rate; OS, overall survival; Pemb, Pembrolizumab; PFS, progression-free survival; Serp, Serplulimab; Tisl, Tislelizumab; Tori, Toripalimab.

    Article Snippet: A small-molecule and a multitarget TKI, Anlotinib, has indicated an increased OS of 2.4 months when applied as a later-line therapy for ES-SCLC patients compared to placebo., Therefore, NMPA has recommended anlotinib as a third-line or subsequent-line treatment option for ES-SCLC patients.

    Techniques: