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mcu i4  (MedChemExpress)


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    MedChemExpress mcu i4
    Mcu I4, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 8 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mcu i4/product/MedChemExpress
    Average 94 stars, based on 8 article reviews
    mcu i4 - by Bioz Stars, 2026-02
    94/100 stars

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    Effect of DSS serum on apoptosis of HT-22. Cells were divided into five groups: HT-22 (H), HT-22+STZ (S), HT-22+STZ+DSS (D),HT-22+STZ <t>+MCUi4(M),</t> HT-22+STZ+DSS+MCUi4 (D+M). ( A ) Results of Western blot. ( B ) Protein expression results of Bax/Bcl-2(n = 3). ( C ) Results of Western blot. ( D ) Protein expression results of p-CaMKII(n = 3). ( E ) Protein expression results of cyt-c(n = 3). ( F ) Protein expression results of cl-Caspase-3 (n = 3). ( G ) Results of Western blot. ( H )Protein expression results of MCU (n = 3). ( I )Apoptosis by flow cytometry. ( J )Apoptosis rate(n = 3). *indicates P < 0.05; **indicates P < 0.01; *** indicates P < 0.001; **** indicates P < 0.0001; ns indicates no statistical difference.
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    Effect of DSS serum on apoptosis of HT-22. Cells were divided into five groups: HT-22 (H), HT-22+STZ (S), HT-22+STZ+DSS (D),HT-22+STZ +MCUi4(M), HT-22+STZ+DSS+MCUi4 (D+M). ( A ) Results of Western blot. ( B ) Protein expression results of Bax/Bcl-2(n = 3). ( C ) Results of Western blot. ( D ) Protein expression results of p-CaMKII(n = 3). ( E ) Protein expression results of cyt-c(n = 3). ( F ) Protein expression results of cl-Caspase-3 (n = 3). ( G ) Results of Western blot. ( H )Protein expression results of MCU (n = 3). ( I )Apoptosis by flow cytometry. ( J )Apoptosis rate(n = 3). *indicates P < 0.05; **indicates P < 0.01; *** indicates P < 0.001; **** indicates P < 0.0001; ns indicates no statistical difference.

    Journal: Drug Design, Development and Therapy

    Article Title: Danggui-Shaoyao-San Can Ameliorate Alzheimer’s Disease by Inhibiting Hippocampal Neuron Apoptosis: Findings from Serum Pharmacology

    doi: 10.2147/DDDT.S490900

    Figure Lengend Snippet: Effect of DSS serum on apoptosis of HT-22. Cells were divided into five groups: HT-22 (H), HT-22+STZ (S), HT-22+STZ+DSS (D),HT-22+STZ +MCUi4(M), HT-22+STZ+DSS+MCUi4 (D+M). ( A ) Results of Western blot. ( B ) Protein expression results of Bax/Bcl-2(n = 3). ( C ) Results of Western blot. ( D ) Protein expression results of p-CaMKII(n = 3). ( E ) Protein expression results of cyt-c(n = 3). ( F ) Protein expression results of cl-Caspase-3 (n = 3). ( G ) Results of Western blot. ( H )Protein expression results of MCU (n = 3). ( I )Apoptosis by flow cytometry. ( J )Apoptosis rate(n = 3). *indicates P < 0.05; **indicates P < 0.01; *** indicates P < 0.001; **** indicates P < 0.0001; ns indicates no statistical difference.

    Article Snippet: The MCU is blocked by treating HT-22 cells with 10μM MCUi4(HY-138620, MCE).

    Techniques: Western Blot, Expressing, Flow Cytometry