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macropatch  (Makita)

 
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    Makita macropatch
    Macropatch, supplied by Makita, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/macropatch/macropatch/10__1016_slash_s0006___3495_ascii40_99_ascii41_77036___0-245-9-45
    Average 90 stars, based on 1 article reviews
    macropatch - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Functional Assay:

    Article Title: Voltage-Dependent Sodium Channel Function Is Regulated Through Membrane Mechanics
    Article Snippet: .. First, the functional conversion of the subunit seen in macropatch recordings may help explain previously observed fast inactivation of Na currents seen in the apparent absence of 1 subunits (Scheuer et al., 1990; Ukomadu et al., 1992; West et al., 1992; Chahine et al., 1994; Makita et al., 1994; Qu et al., 1994). ..



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    EPSCs after stimulation of the SCE and FCE.A, Type I fiber. Twin pulse stimulation of the SCE generating two EPSCs, the first by release of one transmitter quantum, the second of three quanta caused by facilitation.Asterisks in A and C mark spontaneously released single quanta. B, EPSCs after twin pulse stimulation of the FCE. The amplitude of the second EPSC is typically smaller than that of the first in type I fibers because of depression of release. C, Direct stimulation of a release bouton of FCE in a type IV fiber with a single pulse through the <t>macropatch</t> electrode. D, Stimulation and recording paradigm for the SCE and FCE. Both axons were stimulated selectively, as shown in A and B, but the FCE usually for a shorter period than the SCE. Only the EPSC amplitudes generated by the second of the twin pulses are plotted. In the experiment shown, 20 min was allowed for equilibration after 10−8m ω-AgaTX application before resuming stimulation and recording. The SCE was stimulated first. The short equilibration time was chosen to show the gradual development of the toxin effect.
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    macropatch  (Makita)
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    EPSCs after stimulation of the SCE and FCE.A, Type I fiber. Twin pulse stimulation of the SCE generating two EPSCs, the first by release of one transmitter quantum, the second of three quanta caused by facilitation.Asterisks in A and C mark spontaneously released single quanta. B, EPSCs after twin pulse stimulation of the FCE. The amplitude of the second EPSC is typically smaller than that of the first in type I fibers because of depression of release. C, Direct stimulation of a release bouton of FCE in a type IV fiber with a single pulse through the <t>macropatch</t> electrode. D, Stimulation and recording paradigm for the SCE and FCE. Both axons were stimulated selectively, as shown in A and B, but the FCE usually for a shorter period than the SCE. Only the EPSC amplitudes generated by the second of the twin pulses are plotted. In the experiment shown, 20 min was allowed for equilibration after 10−8m ω-AgaTX application before resuming stimulation and recording. The SCE was stimulated first. The short equilibration time was chosen to show the gradual development of the toxin effect.
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    Image Search Results


    EPSCs after stimulation of the SCE and FCE.A, Type I fiber. Twin pulse stimulation of the SCE generating two EPSCs, the first by release of one transmitter quantum, the second of three quanta caused by facilitation.Asterisks in A and C mark spontaneously released single quanta. B, EPSCs after twin pulse stimulation of the FCE. The amplitude of the second EPSC is typically smaller than that of the first in type I fibers because of depression of release. C, Direct stimulation of a release bouton of FCE in a type IV fiber with a single pulse through the macropatch electrode. D, Stimulation and recording paradigm for the SCE and FCE. Both axons were stimulated selectively, as shown in A and B, but the FCE usually for a shorter period than the SCE. Only the EPSC amplitudes generated by the second of the twin pulses are plotted. In the experiment shown, 20 min was allowed for equilibration after 10−8m ω-AgaTX application before resuming stimulation and recording. The SCE was stimulated first. The short equilibration time was chosen to show the gradual development of the toxin effect.

    Journal: The Journal of Neuroscience

    Article Title: The Neuromuscular Junctions of the Slow and the Fast Excitatory Axon in the Closer of the Crab Eriphia spinifrons Are Endowed with Different Ca 2+ Channel Types and Allow Neuron-Specific Modulation of Transmitter Release by Two Neuropeptides

    doi: 10.1523/JNEUROSCI.22-03-00708.2002

    Figure Lengend Snippet: EPSCs after stimulation of the SCE and FCE.A, Type I fiber. Twin pulse stimulation of the SCE generating two EPSCs, the first by release of one transmitter quantum, the second of three quanta caused by facilitation.Asterisks in A and C mark spontaneously released single quanta. B, EPSCs after twin pulse stimulation of the FCE. The amplitude of the second EPSC is typically smaller than that of the first in type I fibers because of depression of release. C, Direct stimulation of a release bouton of FCE in a type IV fiber with a single pulse through the macropatch electrode. D, Stimulation and recording paradigm for the SCE and FCE. Both axons were stimulated selectively, as shown in A and B, but the FCE usually for a shorter period than the SCE. Only the EPSC amplitudes generated by the second of the twin pulses are plotted. In the experiment shown, 20 min was allowed for equilibration after 10−8m ω-AgaTX application before resuming stimulation and recording. The SCE was stimulated first. The short equilibration time was chosen to show the gradual development of the toxin effect.

    Article Snippet: The macropatch electrode is specific for current recording within the region of the electrode lumen with an amplifier designed for stimulating and recording from individual release sites (Zeitz Instruments, Augsburg, Germany).

    Techniques: Generated