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ku80 polyclonal antibody  (Proteintech)


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    Structured Review

    Proteintech ku80 polyclonal antibody
    Ku80 Polyclonal Antibody, supplied by Proteintech, used in various techniques. Bioz Stars score: 94/100, based on 43 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ku80 polyclonal antibody/product/Proteintech
    Average 94 stars, based on 43 article reviews
    ku80 polyclonal antibody - by Bioz Stars, 2026-03
    94/100 stars

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    ATCC mouse embryonic fibroblasts
    a , Schematic overview of the mouse Apc gene, 20 amino acid (AA) β-catenin binding sites are labelled in green and sgRNA target sites are marked with arrows. b , Schematic illustration of the TOP-GFP Wnt reporter construct. c , Mutation-dependent upregulation of Wnt signalling as measured by GFP expression (n=5). d, e , Axin2 ( d ) and Notum ( e ) expression in mouse embryonic <t>fibroblast</t> (MEF) β-catenin binding site cell lines and control lines (n=3). f, g , Schematic illustration of proximal small intestinal wild-type organoids targeted with CRISPR/Cas9 to introduce specific alterations in the number of β-catenin binding sites ( f ) and representative phase images of transduced organoids ( g ). h, i , Relative Axin2 ( h ) and Notum ( i ) expression in β-catenin binding site organoid lines and control lines (n=3).
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    ATCC mouse embryonic fibroblast cells
    a , Schematic overview of the mouse Apc gene, 20 amino acid (AA) β-catenin binding sites are labelled in green and sgRNA target sites are marked with arrows. b , Schematic illustration of the TOP-GFP Wnt reporter construct. c , Mutation-dependent upregulation of Wnt signalling as measured by GFP expression (n=5). d, e , Axin2 ( d ) and Notum ( e ) expression in mouse embryonic <t>fibroblast</t> (MEF) β-catenin binding site cell lines and control lines (n=3). f, g , Schematic illustration of proximal small intestinal wild-type organoids targeted with CRISPR/Cas9 to introduce specific alterations in the number of β-catenin binding sites ( f ) and representative phase images of transduced organoids ( g ). h, i , Relative Axin2 ( h ) and Notum ( i ) expression in β-catenin binding site organoid lines and control lines (n=3).
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    Image Search Results


    a , Schematic overview of the mouse Apc gene, 20 amino acid (AA) β-catenin binding sites are labelled in green and sgRNA target sites are marked with arrows. b , Schematic illustration of the TOP-GFP Wnt reporter construct. c , Mutation-dependent upregulation of Wnt signalling as measured by GFP expression (n=5). d, e , Axin2 ( d ) and Notum ( e ) expression in mouse embryonic fibroblast (MEF) β-catenin binding site cell lines and control lines (n=3). f, g , Schematic illustration of proximal small intestinal wild-type organoids targeted with CRISPR/Cas9 to introduce specific alterations in the number of β-catenin binding sites ( f ) and representative phase images of transduced organoids ( g ). h, i , Relative Axin2 ( h ) and Notum ( i ) expression in β-catenin binding site organoid lines and control lines (n=3).

    Journal: bioRxiv

    Article Title: Apc truncation enforces optimal Wnt signalling during early intestinal tumourigenesis

    doi: 10.64898/2026.02.11.705236

    Figure Lengend Snippet: a , Schematic overview of the mouse Apc gene, 20 amino acid (AA) β-catenin binding sites are labelled in green and sgRNA target sites are marked with arrows. b , Schematic illustration of the TOP-GFP Wnt reporter construct. c , Mutation-dependent upregulation of Wnt signalling as measured by GFP expression (n=5). d, e , Axin2 ( d ) and Notum ( e ) expression in mouse embryonic fibroblast (MEF) β-catenin binding site cell lines and control lines (n=3). f, g , Schematic illustration of proximal small intestinal wild-type organoids targeted with CRISPR/Cas9 to introduce specific alterations in the number of β-catenin binding sites ( f ) and representative phase images of transduced organoids ( g ). h, i , Relative Axin2 ( h ) and Notum ( i ) expression in β-catenin binding site organoid lines and control lines (n=3).

    Article Snippet: Mouse embryonic fibroblasts (MEFs, ATCC) were cultured in DMEM (Gibco), supplemented with 10% FCS, 1% glutamine and an antibiotic penicillin-streptomycin solution.

    Techniques: Binding Assay, Construct, Mutagenesis, Expressing, Control, CRISPR, Introduce