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wnt pathway inhibitor iwr 1  (MedChemExpress)


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    Structured Review

    MedChemExpress wnt pathway inhibitor iwr 1
    Wnt Pathway Inhibitor Iwr 1, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 96/100, based on 98 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/iwr-1/IWR-1/pm42785530-74-1-15
    Average 96 stars, based on 98 article reviews
    wnt pathway inhibitor iwr 1 - by Bioz Stars, 2026-10
    96/100 stars

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    Related Articles

    shRNA:

    Article Title: PDZK1-ULK1 Axis Triggers Lipophagy to Inhibit Tumor Progression and Sunitinib Resistance in Clear Cell Renal Cell Carcinoma.
    Article Snippet: io (Beijing, China); 3-Methyladenine (#S2767) and LYN-1604 (#S8597) from Selleck (Houston, Texas, USA); Rapamycin (#HY10219), IWR-1 (#HY-12238), CHIR-98014 (#HY-13076), and Sunitinib (#HY-10255A) from MedChemExpress (Shanghai, China). Small interfering RNAs (siRNAs) were sourced from Sangon Biotech (Shanghai, China). PDZK1 shRNA and control shRNA were obtained from Santa Cruz Biotechnology (Dallas,

    Plasmid Preparation:

    Article Title: PDZK1-ULK1 Axis Triggers Lipophagy to Inhibit Tumor Progression and Sunitinib Resistance in Clear Cell Renal Cell Carcinoma.
    Article Snippet: io (Beijing, China); 3-Methyladenine (#S2767) and LYN-1604 (#S8597) from Selleck (Houston, Texas, USA); Rapamycin (#HY10219), IWR-1 (#HY-12238), CHIR-98014 (#HY-13076), and Sunitinib (#HY-10255A) from MedChemExpress (Shanghai, China). Small interfering RNAs (siRNAs) were sourced from Sangon Biotech (Shanghai, China). PDZK1 shRNA and control shRNA were obtained from Santa Cruz Biotechnology (Dallas,

    Control:

    Article Title: PDZK1-ULK1 Axis Triggers Lipophagy to Inhibit Tumor Progression and Sunitinib Resistance in Clear Cell Renal Cell Carcinoma.
    Article Snippet: io (Beijing, China); 3-Methyladenine (#S2767) and LYN-1604 (#S8597) from Selleck (Houston, Texas, USA); Rapamycin (#HY10219), IWR-1 (#HY-12238), CHIR-98014 (#HY-13076), and Sunitinib (#HY-10255A) from MedChemExpress (Shanghai, China). Small interfering RNAs (siRNAs) were sourced from Sangon Biotech (Shanghai, China). PDZK1 shRNA and control shRNA were obtained from Santa Cruz Biotechnology (Dallas,

    Mouse Assay:

    Article Title: PDZK1-ULK1 Axis Triggers Lipophagy to Inhibit Tumor Progression and Sunitinib Resistance in Clear Cell Renal Cell Carcinoma.
    Article Snippet: io (Beijing, China); 3-Methyladenine (#S2767) and LYN-1604 (#S8597) from Selleck (Houston, Texas, USA); Rapamycin (#HY10219), IWR-1 (#HY-12238), CHIR-98014 (#HY-13076), and Sunitinib (#HY-10255A) from MedChemExpress (Shanghai, China). Small interfering RNAs (siRNAs) were sourced from Sangon Biotech (Shanghai, China). PDZK1 shRNA and control shRNA were obtained from Santa Cruz Biotechnology (Dallas,

    Whole Genome Amplification:

    Article Title: PDZK1-ULK1 Axis Triggers Lipophagy to Inhibit Tumor Progression and Sunitinib Resistance in Clear Cell Renal Cell Carcinoma.
    Article Snippet: io (Beijing, China); 3-Methyladenine (#S2767) and LYN-1604 (#S8597) from Selleck (Houston, Texas, USA); Rapamycin (#HY10219), IWR-1 (#HY-12238), CHIR-98014 (#HY-13076), and Sunitinib (#HY-10255A) from MedChemExpress (Shanghai, China). Small interfering RNAs (siRNAs) were sourced from Sangon Biotech (Shanghai, China). PDZK1 shRNA and control shRNA were obtained from Santa Cruz Biotechnology (Dallas,

    In Vitro:

    Article Title: PDZK1-ULK1 Axis Triggers Lipophagy to Inhibit Tumor Progression and Sunitinib Resistance in Clear Cell Renal Cell Carcinoma.
    Article Snippet: io (Beijing, China); 3-Methyladenine (#S2767) and LYN-1604 (#S8597) from Selleck (Houston, Texas, USA); Rapamycin (#HY10219), IWR-1 (#HY-12238), CHIR-98014 (#HY-13076), and Sunitinib (#HY-10255A) from MedChemExpress (Shanghai, China). Small interfering RNAs (siRNAs) were sourced from Sangon Biotech (Shanghai, China). PDZK1 shRNA and control shRNA were obtained from Santa Cruz Biotechnology (Dallas,



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    XBTYF regulates Hoxb4-dependent activation of the Wnt/β-catenin pathway and attenuates apoptosis in OGD/R-injured H9C2 cells. (A) EdU assay for assessing H9C2 cell proliferation, (B) Calcein-AM/PI for evaluating cell apoptosis. XBTYF: 0.8 mg/mL, <t>IWR-1:</t> 10 μM. * p < 0.05, ** p < 0.01, n = 3. Scale bar: 100 μm.
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    Image Search Results


    XBTYF regulates Hoxb4-dependent activation of the Wnt/β-catenin pathway and attenuates apoptosis in OGD/R-injured H9C2 cells. (A) EdU assay for assessing H9C2 cell proliferation, (B) Calcein-AM/PI for evaluating cell apoptosis. XBTYF: 0.8 mg/mL, IWR-1: 10 μM. * p < 0.05, ** p < 0.01, n = 3. Scale bar: 100 μm.

    Journal: Frontiers in Immunology

    Article Title: Hoxb4 upregulation by Xuan Bi Tong Yu Fang confers cardioprotection via repression of the Wnt/β-catenin pathway in myocardial ischemia-reperfusion injury

    doi: 10.3389/fimmu.2026.1767595

    Figure Lengend Snippet: XBTYF regulates Hoxb4-dependent activation of the Wnt/β-catenin pathway and attenuates apoptosis in OGD/R-injured H9C2 cells. (A) EdU assay for assessing H9C2 cell proliferation, (B) Calcein-AM/PI for evaluating cell apoptosis. XBTYF: 0.8 mg/mL, IWR-1: 10 μM. * p < 0.05, ** p < 0.01, n = 3. Scale bar: 100 μm.

    Article Snippet: IWR-1 (HY-12238) was purchased from MCE (New Jersey, USA).

    Techniques: Activation Assay, EdU Assay

    WB analysis of Wnt/β-catenin pathway in H9C2 cells after OGD/R injury, showing the effect of XBTYF via Hoxb4 on Wnt/β-catenin pathway activation. XBTYF: 0.8 mg/mL, IWR-1: 10 μM. * p < 0.05, ** p < 0.01, n = 3.

    Journal: Frontiers in Immunology

    Article Title: Hoxb4 upregulation by Xuan Bi Tong Yu Fang confers cardioprotection via repression of the Wnt/β-catenin pathway in myocardial ischemia-reperfusion injury

    doi: 10.3389/fimmu.2026.1767595

    Figure Lengend Snippet: WB analysis of Wnt/β-catenin pathway in H9C2 cells after OGD/R injury, showing the effect of XBTYF via Hoxb4 on Wnt/β-catenin pathway activation. XBTYF: 0.8 mg/mL, IWR-1: 10 μM. * p < 0.05, ** p < 0.01, n = 3.

    Article Snippet: IWR-1 (HY-12238) was purchased from MCE (New Jersey, USA).

    Techniques: Activation Assay