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itraconazole  (MedChemExpress)


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    MedChemExpress itraconazole
    Itraconazole, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 26 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/itraconazole/product/MedChemExpress
    Average 93 stars, based on 26 article reviews
    itraconazole - by Bioz Stars, 2026-02
    93/100 stars

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    ( A ) Clove essential oil MIC, ( B ) Clove essential oil MFC, ( C ) Itraconazole MIC.

    Journal: Scientific Reports

    Article Title: Pathologic evaluation of Syzygium aromaticum essential oil against pulmonary aspergillosis in non-neutropenic immunosuppressed rabbits

    doi: 10.1038/s41598-025-34405-5

    Figure Lengend Snippet: ( A ) Clove essential oil MIC, ( B ) Clove essential oil MFC, ( C ) Itraconazole MIC.

    Article Snippet: The fungicidal kinetics of Syzygium aromaticum essential oil (Clove EO) and itraconazole against Aspergillus fumigatus (ATCC 13073) were evaluated using a time-kill assay according to established methodologies with modifications.

    Techniques:

    ( A ) Clove essential oil time-killing curve, ( B ) Itraconazole time-killing curve.

    Journal: Scientific Reports

    Article Title: Pathologic evaluation of Syzygium aromaticum essential oil against pulmonary aspergillosis in non-neutropenic immunosuppressed rabbits

    doi: 10.1038/s41598-025-34405-5

    Figure Lengend Snippet: ( A ) Clove essential oil time-killing curve, ( B ) Itraconazole time-killing curve.

    Article Snippet: The fungicidal kinetics of Syzygium aromaticum essential oil (Clove EO) and itraconazole against Aspergillus fumigatus (ATCC 13073) were evaluated using a time-kill assay according to established methodologies with modifications.

    Techniques:

    CT scans on days 0, 7, and 13 post-inoculations with Aspergillus fumigatus ATCC 13073. ( A ) Day 0 and before fungal inoculation, (1) negative control group, (2) positive control group (3) clove essential oil at 20 mg/kg (4) clove essential oil at 10 mg/kg ( B ) Day 7 post-inoculation, (1) negative control group, (2) positive control group (3) clove essential oil at 20 mg/kg (4) clove essential oil at 10 mg/kg ( C ) Day 13 post-inoculation (1) negative control group, (2) positive control group (3) clove essential oil at 20 mg/kg (4) clove essential oil at 10 mg/kg. The arrow shows nodular lesions involved rabbits’ lungs.

    Journal: Scientific Reports

    Article Title: Pathologic evaluation of Syzygium aromaticum essential oil against pulmonary aspergillosis in non-neutropenic immunosuppressed rabbits

    doi: 10.1038/s41598-025-34405-5

    Figure Lengend Snippet: CT scans on days 0, 7, and 13 post-inoculations with Aspergillus fumigatus ATCC 13073. ( A ) Day 0 and before fungal inoculation, (1) negative control group, (2) positive control group (3) clove essential oil at 20 mg/kg (4) clove essential oil at 10 mg/kg ( B ) Day 7 post-inoculation, (1) negative control group, (2) positive control group (3) clove essential oil at 20 mg/kg (4) clove essential oil at 10 mg/kg ( C ) Day 13 post-inoculation (1) negative control group, (2) positive control group (3) clove essential oil at 20 mg/kg (4) clove essential oil at 10 mg/kg. The arrow shows nodular lesions involved rabbits’ lungs.

    Article Snippet: The fungicidal kinetics of Syzygium aromaticum essential oil (Clove EO) and itraconazole against Aspergillus fumigatus (ATCC 13073) were evaluated using a time-kill assay according to established methodologies with modifications.

    Techniques: Negative Control, Positive Control

    Macroscopic and microscopic figures of lung on 7-day post-inoculation to the Aspergillus fumigatus strain ATCC 13073. ( A ) Negative control group (1) Macroscopic view of a rabbit lung , (2) Extensive pulmonary involvement (star). (3) Accumulation of proteinaceous material and edema (star). (4) Multifocal necrosis (arrowheads) and giant cell (arrow). ( B ) Positive control group (1) Macroscopic view of a rabbit lung (2) Significant pulmonary involvement. (3) Alveolar atelectasia and mild pulmonary involvement, H&E. (4) giant cell (arrow). ( C ) Clove essential oil at 20 mg/kg (1) Macroscopic view of a rabbit lung (2) Extensive pulmonary involvement along with hemorrhage (star). (3) Accumulation of proteinaceous material and edema (star). (4) focal necrosis (arrowhead) and giant cell (arrow). ( D ) Clove essential oil at 10 mg/kg (1) Macroscopic view of a rabbit lung (2) Extensive pulmonary involvement. (3) Multifocal necrosis (arrowheads). (4) giant cell (arrow), H&E.

    Journal: Scientific Reports

    Article Title: Pathologic evaluation of Syzygium aromaticum essential oil against pulmonary aspergillosis in non-neutropenic immunosuppressed rabbits

    doi: 10.1038/s41598-025-34405-5

    Figure Lengend Snippet: Macroscopic and microscopic figures of lung on 7-day post-inoculation to the Aspergillus fumigatus strain ATCC 13073. ( A ) Negative control group (1) Macroscopic view of a rabbit lung , (2) Extensive pulmonary involvement (star). (3) Accumulation of proteinaceous material and edema (star). (4) Multifocal necrosis (arrowheads) and giant cell (arrow). ( B ) Positive control group (1) Macroscopic view of a rabbit lung (2) Significant pulmonary involvement. (3) Alveolar atelectasia and mild pulmonary involvement, H&E. (4) giant cell (arrow). ( C ) Clove essential oil at 20 mg/kg (1) Macroscopic view of a rabbit lung (2) Extensive pulmonary involvement along with hemorrhage (star). (3) Accumulation of proteinaceous material and edema (star). (4) focal necrosis (arrowhead) and giant cell (arrow). ( D ) Clove essential oil at 10 mg/kg (1) Macroscopic view of a rabbit lung (2) Extensive pulmonary involvement. (3) Multifocal necrosis (arrowheads). (4) giant cell (arrow), H&E.

    Article Snippet: The fungicidal kinetics of Syzygium aromaticum essential oil (Clove EO) and itraconazole against Aspergillus fumigatus (ATCC 13073) were evaluated using a time-kill assay according to established methodologies with modifications.

    Techniques: Negative Control, Positive Control

    Macroscopic and microscopic Figures of lung on 13-day post-inoculation to the Aspergillus fumigatus strain ATCC 13073. ( A ) Negative control group (1) Macroscopic view of rabbit lung , (2) Extensive pulmonary involvement along with pyogranulomas (arrowhead). (3) Accumulation of neutrophils within alveolar spaces (arrowheads). (4) Multifocal Splendore-Hoeppli phenomenon formation (arrow), H&E. ( B ) Positive control group (1) Macroscopic view of rabbit lung (2) Focal pulmonary involvement (star). (3) Focal pulmonary involvement and giant cell (arrowhead), H&E. (4) Multifocal Splendore-Hoeppli phenomenon formation (arrow). ( C ) Clove essential oil at 20 mg/kg (1) Macroscopic view of rabbit lung (2) Focal pulmonary involvement (star). (3) Focal pulmonary involvement and Splendore-Hoeppli phenomenon formation (arrow). (4) Focal Splendore-Hoeppli phenomenon formation (arrow). ( D ) Clove essential oil at 10 mg/kg (1) Macroscopic view of rabbit lung (2) Extensive pulmonary involvement accompanied by perivascular inflammation (arrowheads). (3) Alveolar atelectasis along with giant cell (arrowhead). (4) Numerous giant cell (arrows), H&E.

    Journal: Scientific Reports

    Article Title: Pathologic evaluation of Syzygium aromaticum essential oil against pulmonary aspergillosis in non-neutropenic immunosuppressed rabbits

    doi: 10.1038/s41598-025-34405-5

    Figure Lengend Snippet: Macroscopic and microscopic Figures of lung on 13-day post-inoculation to the Aspergillus fumigatus strain ATCC 13073. ( A ) Negative control group (1) Macroscopic view of rabbit lung , (2) Extensive pulmonary involvement along with pyogranulomas (arrowhead). (3) Accumulation of neutrophils within alveolar spaces (arrowheads). (4) Multifocal Splendore-Hoeppli phenomenon formation (arrow), H&E. ( B ) Positive control group (1) Macroscopic view of rabbit lung (2) Focal pulmonary involvement (star). (3) Focal pulmonary involvement and giant cell (arrowhead), H&E. (4) Multifocal Splendore-Hoeppli phenomenon formation (arrow). ( C ) Clove essential oil at 20 mg/kg (1) Macroscopic view of rabbit lung (2) Focal pulmonary involvement (star). (3) Focal pulmonary involvement and Splendore-Hoeppli phenomenon formation (arrow). (4) Focal Splendore-Hoeppli phenomenon formation (arrow). ( D ) Clove essential oil at 10 mg/kg (1) Macroscopic view of rabbit lung (2) Extensive pulmonary involvement accompanied by perivascular inflammation (arrowheads). (3) Alveolar atelectasis along with giant cell (arrowhead). (4) Numerous giant cell (arrows), H&E.

    Article Snippet: The fungicidal kinetics of Syzygium aromaticum essential oil (Clove EO) and itraconazole against Aspergillus fumigatus (ATCC 13073) were evaluated using a time-kill assay according to established methodologies with modifications.

    Techniques: Negative Control, Positive Control

    Histochemistry and Immunohistochemistry examination of rabbits’ lungs on 13-day post-inoculation to the Aspergillus fumigatus strain ATCC 13073. ( A ) Negative control group (1) The arrow shows fungal structure, GMS staining (2) Extensive expression of CD68. (3) Remarkable expression of CD163. (4) Extensive expression of MPO. ( B ) Positive control group (1) The arrow shows fungal structure, GMS staining (2) Low expression of CD68. (3) Insignificant expression of CD163. (4) Mild expression of MPO. ( C ) Clove essential oil at 20 mg/kg (1) The arrow shows fungal structure, GMS staining. (2) Low expression of CD68. (3) Insignificant expression of CD163. (4) Mild expression of MPO. ( D ) Clove essential oil at 10 mg/kg (1) The arrow shows fungal structure, GMS staining (2) Significant expression of CD68. (3) Moderate expression of CD163. (4) Relatively notable expression of MPO.

    Journal: Scientific Reports

    Article Title: Pathologic evaluation of Syzygium aromaticum essential oil against pulmonary aspergillosis in non-neutropenic immunosuppressed rabbits

    doi: 10.1038/s41598-025-34405-5

    Figure Lengend Snippet: Histochemistry and Immunohistochemistry examination of rabbits’ lungs on 13-day post-inoculation to the Aspergillus fumigatus strain ATCC 13073. ( A ) Negative control group (1) The arrow shows fungal structure, GMS staining (2) Extensive expression of CD68. (3) Remarkable expression of CD163. (4) Extensive expression of MPO. ( B ) Positive control group (1) The arrow shows fungal structure, GMS staining (2) Low expression of CD68. (3) Insignificant expression of CD163. (4) Mild expression of MPO. ( C ) Clove essential oil at 20 mg/kg (1) The arrow shows fungal structure, GMS staining. (2) Low expression of CD68. (3) Insignificant expression of CD163. (4) Mild expression of MPO. ( D ) Clove essential oil at 10 mg/kg (1) The arrow shows fungal structure, GMS staining (2) Significant expression of CD68. (3) Moderate expression of CD163. (4) Relatively notable expression of MPO.

    Article Snippet: The fungicidal kinetics of Syzygium aromaticum essential oil (Clove EO) and itraconazole against Aspergillus fumigatus (ATCC 13073) were evaluated using a time-kill assay according to established methodologies with modifications.

    Techniques: Immunohistochemistry, Negative Control, Staining, Expressing, Positive Control