inflammation  (MedChemExpress)

Journal: iScience

Article Title: Olink proteomics reveals TNFRSF9 as a biomarker for abdominal aortic aneurysms

doi: 10.1016/j.isci.2025.112828

Figure Lengend Snippet: Predictive value of NPX values and ELISA values for IL-6 and TNFRSF9 (A) Olink data visualization of TNFRSF9. (B) Olink data visualization of IL-6. (C) Receiver operating characteristic (ROC) curve of TNFRSF9 concentrations based on Olink data between AAA and control groups. (D) ROC curve of IL-6 concentrations based on Olink data in the AAA and control groups. (E) ROC curve of IL-6+TNFRSF9 concentrations based on Olink data in the AAA and control groups. (F) ELISA data visualization of TNFRSF9. (G) ELISA data visualization of IL-6. (H) ROC curve of TNFRSF9 based on ELISA data in the AAA and control groups. (I) ROC curve of IL-6 concentrations based on ELISA data in the AAA and control groups. (J) ROC curve of IL-6+TNFRSF9 concentrations based on ELISA data in the AAA and control groups. Data are represented as mean ± SEMs. Statistical analysis between the two groups was performed using a t test. Significance levels are annotated as follows: ns = not significant, ∗ = p value < 0.05, ∗∗ = p value < 0.01, ∗∗∗ = p value < 0.001, ∗∗∗∗ = p value < 0.0001.

Article Snippet: Olink proteomics-based analysis of serum inflammatory biomarkers has been applied to a variety of diseases, such as adolescent depression, acute osteofascial compartment syndrome, and preeclampsia., , In this study, the Olink PEA inflammation panel was utilized to identify differences in the expression of different inflammatory proteins between healthy individuals and patients with AAA.

Techniques: Enzyme-linked Immunosorbent Assay, Control