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gdc 0077  (MedChemExpress)


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    MedChemExpress gdc 0077
    Inhibition of cervical cancer cell lines by PI3K α inhibitors. The maximum dose for each cell line was selected, and the percentage inhibition was compared with the corresponding control. (A) Alpelisib (BYL-719). (B) Inavolisib <t>(GDC-0077).</t> All cell lines have PIK3CA mutations except SiHa. **** = p < 0.0001 by one-way ANOVA and Dunnett’s multiple comparison test. <20% inhibition interpreted as no or negative response.
    Gdc 0077, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/gdc 0077/product/MedChemExpress
    Average 94 stars, based on 7 article reviews
    gdc 0077 - by Bioz Stars, 2026-05
    94/100 stars

    Images

    1) Product Images from "PIK3CA mutant cervical cancer is selectively suppressed by PI3Kα inhibition (Alpelisib/BYL-719 and Inavolisib/GDC-0077) and cooperates with HPV directed T cell therapy"

    Article Title: PIK3CA mutant cervical cancer is selectively suppressed by PI3Kα inhibition (Alpelisib/BYL-719 and Inavolisib/GDC-0077) and cooperates with HPV directed T cell therapy

    Journal: Neoplasia (New York, N.Y.)

    doi: 10.1016/j.neo.2026.101305

    Inhibition of cervical cancer cell lines by PI3K α inhibitors. The maximum dose for each cell line was selected, and the percentage inhibition was compared with the corresponding control. (A) Alpelisib (BYL-719). (B) Inavolisib (GDC-0077). All cell lines have PIK3CA mutations except SiHa. **** = p < 0.0001 by one-way ANOVA and Dunnett’s multiple comparison test. <20% inhibition interpreted as no or negative response.
    Figure Legend Snippet: Inhibition of cervical cancer cell lines by PI3K α inhibitors. The maximum dose for each cell line was selected, and the percentage inhibition was compared with the corresponding control. (A) Alpelisib (BYL-719). (B) Inavolisib (GDC-0077). All cell lines have PIK3CA mutations except SiHa. **** = p < 0.0001 by one-way ANOVA and Dunnett’s multiple comparison test. <20% inhibition interpreted as no or negative response.

    Techniques Used: Inhibition, Control, Comparison



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    Image Search Results


    Inhibition of cervical cancer cell lines by PI3K α inhibitors. The maximum dose for each cell line was selected, and the percentage inhibition was compared with the corresponding control. (A) Alpelisib (BYL-719). (B) Inavolisib (GDC-0077). All cell lines have PIK3CA mutations except SiHa. **** = p < 0.0001 by one-way ANOVA and Dunnett’s multiple comparison test. <20% inhibition interpreted as no or negative response.

    Journal: Neoplasia (New York, N.Y.)

    Article Title: PIK3CA mutant cervical cancer is selectively suppressed by PI3Kα inhibition (Alpelisib/BYL-719 and Inavolisib/GDC-0077) and cooperates with HPV directed T cell therapy

    doi: 10.1016/j.neo.2026.101305

    Figure Lengend Snippet: Inhibition of cervical cancer cell lines by PI3K α inhibitors. The maximum dose for each cell line was selected, and the percentage inhibition was compared with the corresponding control. (A) Alpelisib (BYL-719). (B) Inavolisib (GDC-0077). All cell lines have PIK3CA mutations except SiHa. **** = p < 0.0001 by one-way ANOVA and Dunnett’s multiple comparison test. <20% inhibition interpreted as no or negative response.

    Article Snippet: GDC-0077 was also purchased from MedChem Express (Cat# HY-101562.

    Techniques: Inhibition, Control, Comparison