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storm imaging human dermal fibroblasts hdfs  (ATCC)


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    ATCC storm imaging human dermal fibroblasts hdfs
    Storm Imaging Human Dermal Fibroblasts Hdfs, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 637 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/storm imaging human dermal fibroblasts hdfs/product/ATCC
    Average 96 stars, based on 637 article reviews
    storm imaging human dermal fibroblasts hdfs - by Bioz Stars, 2026-03
    96/100 stars

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    Pan-HDACi panobinostat and belinostat improve adenine base editing (A) Schematic of the Xmas reporter that allows EGFP co-expression with mCherry under a shared EF-1a promoter. (B) A to G (A>G) base editing percentage normalized to control for background noise in five biological replicates each of <t>Hs68,</t> HeLa, MCF10A, and Jurkat cells treated with panobinostat (blue), SB505124 (red), PCI-24781/abexinostat (yellow), or VPA (cyan). (C) Average fold-editing in the indicated cell lines. Colors are as in (B). (D) Cumulative editing fold change with panobinostat or belinostat treatment. n = 5 biological replicates. All p values are from non-parametric one-way ANOVA corrected for multiple comparisons by controlling FDR using the two-stage stepup method of Benjamini, Krieger, and Yekutieli. See also .
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    Image Search Results


    Pan-HDACi panobinostat and belinostat improve adenine base editing (A) Schematic of the Xmas reporter that allows EGFP co-expression with mCherry under a shared EF-1a promoter. (B) A to G (A>G) base editing percentage normalized to control for background noise in five biological replicates each of Hs68, HeLa, MCF10A, and Jurkat cells treated with panobinostat (blue), SB505124 (red), PCI-24781/abexinostat (yellow), or VPA (cyan). (C) Average fold-editing in the indicated cell lines. Colors are as in (B). (D) Cumulative editing fold change with panobinostat or belinostat treatment. n = 5 biological replicates. All p values are from non-parametric one-way ANOVA corrected for multiple comparisons by controlling FDR using the two-stage stepup method of Benjamini, Krieger, and Yekutieli. See also .

    Journal: Cell Reports Methods

    Article Title: FAME-CRISPR improves CRISPR-Cas9 genome editing via HDAC inhibition and engineered virus-like particle delivery

    doi: 10.1016/j.crmeth.2025.101248

    Figure Lengend Snippet: Pan-HDACi panobinostat and belinostat improve adenine base editing (A) Schematic of the Xmas reporter that allows EGFP co-expression with mCherry under a shared EF-1a promoter. (B) A to G (A>G) base editing percentage normalized to control for background noise in five biological replicates each of Hs68, HeLa, MCF10A, and Jurkat cells treated with panobinostat (blue), SB505124 (red), PCI-24781/abexinostat (yellow), or VPA (cyan). (C) Average fold-editing in the indicated cell lines. Colors are as in (B). (D) Cumulative editing fold change with panobinostat or belinostat treatment. n = 5 biological replicates. All p values are from non-parametric one-way ANOVA corrected for multiple comparisons by controlling FDR using the two-stage stepup method of Benjamini, Krieger, and Yekutieli. See also .

    Article Snippet: HeLa (CCL-2), HepG2 (HB-8065), U2OS (HTB-96), Hs68 (CRL-1635), Jurkat (TIB-152) and HEK-293T (CRL-3216) cell lines were obtained from the American Type Culture Collection (ATCC).

    Techniques: Expressing, Control

    Panobinostat and belinostat improve cytosine base editing (A) C to T (C>T) base editing percentage normalized to control background noise in nine biological replicates for Hs68 using eVLPs co-transducing three sgRNA targeting three loci in the EGFP sequence coupled with panobinostat (blue) or belinostat (red) treatment. (B) Average editing fold change for Hs68 cells after panobinostat or belinostat treatment. (C) Cumulative fold change in editing after panobinostat or belinostat treatment. n = 9 biological replicates. p values from non-parametric one-way ANOVA corrected for multiple comparisons by controlling FDR using the two-stage stepup method of Benjamini, Krieger, and Yekutieli. (D) Step-by-step protocol for HDACi-supplemented, eVLP-mediated gene editing. See also and and .

    Journal: Cell Reports Methods

    Article Title: FAME-CRISPR improves CRISPR-Cas9 genome editing via HDAC inhibition and engineered virus-like particle delivery

    doi: 10.1016/j.crmeth.2025.101248

    Figure Lengend Snippet: Panobinostat and belinostat improve cytosine base editing (A) C to T (C>T) base editing percentage normalized to control background noise in nine biological replicates for Hs68 using eVLPs co-transducing three sgRNA targeting three loci in the EGFP sequence coupled with panobinostat (blue) or belinostat (red) treatment. (B) Average editing fold change for Hs68 cells after panobinostat or belinostat treatment. (C) Cumulative fold change in editing after panobinostat or belinostat treatment. n = 9 biological replicates. p values from non-parametric one-way ANOVA corrected for multiple comparisons by controlling FDR using the two-stage stepup method of Benjamini, Krieger, and Yekutieli. (D) Step-by-step protocol for HDACi-supplemented, eVLP-mediated gene editing. See also and and .

    Article Snippet: HeLa (CCL-2), HepG2 (HB-8065), U2OS (HTB-96), Hs68 (CRL-1635), Jurkat (TIB-152) and HEK-293T (CRL-3216) cell lines were obtained from the American Type Culture Collection (ATCC).

    Techniques: Control, Sequencing