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hoxb8  (Bioss)


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    Bioss hoxb8
    Hoxb8, supplied by Bioss, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hoxb8/pm41718768-18-67-69?v=Bioss
    Average 94 stars, based on 1 article reviews
    hoxb8 - by Bioz Stars, 2026-07
    94/100 stars

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    Image Search Results


    Validation of HOXB8 transfection and its effects on proliferation, migration, and invasion of SKOV3 cells. (A) RT-qPCR analysis confirming HOXB8 expression in each group to verify transfection efficiency. (B) CCK-8 assay SKOV3 cell proliferation. (C) Wound healing assay evaluating the migratory ability of SKOV3 cells after HOXB8 modulation, with representative images at 0 and 24 h. (D) Transwell invasion assay measuring the invasive ability of SKOV3 cells (staining method: crystal violet staining). Data are presented as mean ± SD (n=3). Statistical evaluations were performed using one-way ANOVA followed by Tukey’s post hoc test. *, P<0.05; **, P<0.01; ***, P<0.001. ANOVA, analysis of variance; CCK-8, Cell Counting Kit-8; NC, negative control; OE, overexpression; RT-qPCR, real-time quantitative polymerase chain reaction; SD, standard deviation.

    Journal: Translational Cancer Research

    Article Title: HOXB8 promotes invasion and metastasis of high-grade serous ovarian cancer via suppression of the KDM6B/C/EBPα signaling axis

    doi: 10.21037/tcr-2025-aw-2272

    Figure Lengend Snippet: Validation of HOXB8 transfection and its effects on proliferation, migration, and invasion of SKOV3 cells. (A) RT-qPCR analysis confirming HOXB8 expression in each group to verify transfection efficiency. (B) CCK-8 assay SKOV3 cell proliferation. (C) Wound healing assay evaluating the migratory ability of SKOV3 cells after HOXB8 modulation, with representative images at 0 and 24 h. (D) Transwell invasion assay measuring the invasive ability of SKOV3 cells (staining method: crystal violet staining). Data are presented as mean ± SD (n=3). Statistical evaluations were performed using one-way ANOVA followed by Tukey’s post hoc test. *, P<0.05; **, P<0.01; ***, P<0.001. ANOVA, analysis of variance; CCK-8, Cell Counting Kit-8; NC, negative control; OE, overexpression; RT-qPCR, real-time quantitative polymerase chain reaction; SD, standard deviation.

    Article Snippet: The HOXB8 overexpression plasmid (pcDNA3.1/HOXB8) and the empty control vector (pcDNA3.1-NC) were constructed and sequence-verified by GeneChem (Shanghai, China).

    Techniques: Biomarker Discovery, Transfection, Migration, Quantitative RT-PCR, Expressing, CCK-8 Assay, Wound Healing Assay, Transwell Invasion Assay, Staining, Cell Counting, Negative Control, Over Expression, Real-time Polymerase Chain Reaction, Standard Deviation

    Regulatory effects of HOXB8 on the KDM6B/C/EBPα/CCND1 signaling axis. (A-C) qPCR analysis for KDM6B (A), C/EBPα (B), and CCND1 (C). (D) Western blot analysis for KDM6B, C/EBPα, CCND1, and H3K27me3. (E) Densitometric quantification of protein bands from (D). Data are presented as mean ± SD (n=3). Statistical evaluations were performed using one-way ANOVA followed by Tukey’s post hoc test. *, P<0.05; **, P<0.01; ***, P<0.001. ANOVA, analysis of variance; NC, negative control; OE, overexpression; qPCR, quantitative polymerase chain reaction; SD, standard deviation.

    Journal: Translational Cancer Research

    Article Title: HOXB8 promotes invasion and metastasis of high-grade serous ovarian cancer via suppression of the KDM6B/C/EBPα signaling axis

    doi: 10.21037/tcr-2025-aw-2272

    Figure Lengend Snippet: Regulatory effects of HOXB8 on the KDM6B/C/EBPα/CCND1 signaling axis. (A-C) qPCR analysis for KDM6B (A), C/EBPα (B), and CCND1 (C). (D) Western blot analysis for KDM6B, C/EBPα, CCND1, and H3K27me3. (E) Densitometric quantification of protein bands from (D). Data are presented as mean ± SD (n=3). Statistical evaluations were performed using one-way ANOVA followed by Tukey’s post hoc test. *, P<0.05; **, P<0.01; ***, P<0.001. ANOVA, analysis of variance; NC, negative control; OE, overexpression; qPCR, quantitative polymerase chain reaction; SD, standard deviation.

    Article Snippet: The HOXB8 overexpression plasmid (pcDNA3.1/HOXB8) and the empty control vector (pcDNA3.1-NC) were constructed and sequence-verified by GeneChem (Shanghai, China).

    Techniques: Western Blot, Negative Control, Over Expression, Real-time Polymerase Chain Reaction, Standard Deviation