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anti hk1  (Proteintech)


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    Structured Review

    Proteintech anti hk1
    Anti Hk1, supplied by Proteintech, used in various techniques. Bioz Stars score: 94/100, based on 69 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hk1/Hexokinase+1+Antibody/pm41932135-155-21-27
    Average 94 stars, based on 69 article reviews
    anti hk1 - by Bioz Stars, 2026-09
    94/100 stars

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    Related Articles

    Western Blot:

    Article Title: TDP-43 impairs glycolysis by sequestering hexokinase 1 in amyotrophic lateral sclerosis
    Article Snippet: The antibody against HK1 (#NBP1-51644; immunofluorescence-tissue 1:50) was purchased from Novus Biologicals (Centennial, CO, USA). .. The antibodies against ATPB (#17247-1-AP; WB 1:2000), cterm-TDP-43 (#12892-1-AP; Co-IP 1:300, IF-tissue 1:100, western blot 1:5000), HK1 (#19662-1-AP; Co-IP 1:300, WB 1:1000), hTDP-43 (#60019-2-Ig; IF-tissue 1:500, IF-cells 1:500), NeuN (#66836-1-Ig; IF-tissue 1:500), PFK (#55028-1-AP; IF-tissue 1:50, IF-cells 1:500, WB 1:2000), TDP-43 (#10782-2-AP; IF-tissue 1:100, western blot 1:2000) were from ProteinTech (Rosemont, IL, USA). .. The antibodies against Enolase (#sc-271384; WB 1:2000) and GFP (#sc-9996; WB 1:5000) were from Santa Cruz Biotechnology (Dallas, TX, USA).

    Article Title: TDP-43 impairs glycolysis by sequestering hexokinase 1 in amyotrophic lateral sclerosis.
    Article Snippet: The antibody against HK1 (#NBP151644; immunofluorescence-tissue 1:50) was purchased from Novus Biologicals (Centennial, CO, USA). .. The antibodies against ATPB (#17247-1-AP; WB 1:2000), ctermTDP-43 (#12892-1-AP; Co-IP 1:300, IF-tissue 1:100, western blot 1:5000), HK1 (#19662-1-AP; Co-IP 1:300, WB 1:1000), hTDP-43 (#60019-2-Ig; IF-tissue 1:500, IF-cells 1:500), NeuN (#66836-1-Ig; IF-tissue 1:500), PFK (#55028-1-AP; IF-tissue 1:50, IF-cells 1:500, WB 1:2000), TDP-43 (#10782-2-AP; IF-tissue 1:100, western blot 1:2000) were from ProteinTech (Rosemont, IL, USA). .. The antibodies against Enolase (#sc-271384; WB 1:2000) and GFP (#sc-9996; WB 1:5000) were from Santa Cruz Biotechnology (Dallas, TX, USA).

    Co-Immunoprecipitation Assay:

    Article Title: TDP-43 impairs glycolysis by sequestering hexokinase 1 in amyotrophic lateral sclerosis
    Article Snippet: The antibody against HK1 (#NBP1-51644; immunofluorescence-tissue 1:50) was purchased from Novus Biologicals (Centennial, CO, USA). .. The antibodies against ATPB (#17247-1-AP; WB 1:2000), cterm-TDP-43 (#12892-1-AP; Co-IP 1:300, IF-tissue 1:100, western blot 1:5000), HK1 (#19662-1-AP; Co-IP 1:300, WB 1:1000), hTDP-43 (#60019-2-Ig; IF-tissue 1:500, IF-cells 1:500), NeuN (#66836-1-Ig; IF-tissue 1:500), PFK (#55028-1-AP; IF-tissue 1:50, IF-cells 1:500, WB 1:2000), TDP-43 (#10782-2-AP; IF-tissue 1:100, western blot 1:2000) were from ProteinTech (Rosemont, IL, USA). .. The antibodies against Enolase (#sc-271384; WB 1:2000) and GFP (#sc-9996; WB 1:5000) were from Santa Cruz Biotechnology (Dallas, TX, USA).

    Article Title: TDP-43 impairs glycolysis by sequestering hexokinase 1 in amyotrophic lateral sclerosis.
    Article Snippet: The antibody against HK1 (#NBP151644; immunofluorescence-tissue 1:50) was purchased from Novus Biologicals (Centennial, CO, USA). .. The antibodies against ATPB (#17247-1-AP; WB 1:2000), ctermTDP-43 (#12892-1-AP; Co-IP 1:300, IF-tissue 1:100, western blot 1:5000), HK1 (#19662-1-AP; Co-IP 1:300, WB 1:1000), hTDP-43 (#60019-2-Ig; IF-tissue 1:500, IF-cells 1:500), NeuN (#66836-1-Ig; IF-tissue 1:500), PFK (#55028-1-AP; IF-tissue 1:50, IF-cells 1:500, WB 1:2000), TDP-43 (#10782-2-AP; IF-tissue 1:100, western blot 1:2000) were from ProteinTech (Rosemont, IL, USA). .. The antibodies against Enolase (#sc-271384; WB 1:2000) and GFP (#sc-9996; WB 1:5000) were from Santa Cruz Biotechnology (Dallas, TX, USA).

    IF-cells:

    Article Title: TDP-43 impairs glycolysis by sequestering hexokinase 1 in amyotrophic lateral sclerosis
    Article Snippet: The antibody against HK1 (#NBP1-51644; immunofluorescence-tissue 1:50) was purchased from Novus Biologicals (Centennial, CO, USA). .. The antibodies against ATPB (#17247-1-AP; WB 1:2000), cterm-TDP-43 (#12892-1-AP; Co-IP 1:300, IF-tissue 1:100, western blot 1:5000), HK1 (#19662-1-AP; Co-IP 1:300, WB 1:1000), hTDP-43 (#60019-2-Ig; IF-tissue 1:500, IF-cells 1:500), NeuN (#66836-1-Ig; IF-tissue 1:500), PFK (#55028-1-AP; IF-tissue 1:50, IF-cells 1:500, WB 1:2000), TDP-43 (#10782-2-AP; IF-tissue 1:100, western blot 1:2000) were from ProteinTech (Rosemont, IL, USA). .. The antibodies against Enolase (#sc-271384; WB 1:2000) and GFP (#sc-9996; WB 1:5000) were from Santa Cruz Biotechnology (Dallas, TX, USA).

    Article Title: TDP-43 impairs glycolysis by sequestering hexokinase 1 in amyotrophic lateral sclerosis.
    Article Snippet: The antibody against HK1 (#NBP151644; immunofluorescence-tissue 1:50) was purchased from Novus Biologicals (Centennial, CO, USA). .. The antibodies against ATPB (#17247-1-AP; WB 1:2000), ctermTDP-43 (#12892-1-AP; Co-IP 1:300, IF-tissue 1:100, western blot 1:5000), HK1 (#19662-1-AP; Co-IP 1:300, WB 1:1000), hTDP-43 (#60019-2-Ig; IF-tissue 1:500, IF-cells 1:500), NeuN (#66836-1-Ig; IF-tissue 1:500), PFK (#55028-1-AP; IF-tissue 1:50, IF-cells 1:500, WB 1:2000), TDP-43 (#10782-2-AP; IF-tissue 1:100, western blot 1:2000) were from ProteinTech (Rosemont, IL, USA). .. The antibodies against Enolase (#sc-271384; WB 1:2000) and GFP (#sc-9996; WB 1:5000) were from Santa Cruz Biotechnology (Dallas, TX, USA).

    other:

    Article Title: Mitochondrial membrane junction-mediated ATP channeling drives activity-dependent glucose metabolism
    Article Snippet: HK1 (Proteintech, 19662-1-AP); HK1 (Invitrogen, MA5-14789); HK1 (Abclonal, A0533); VDAC1 (Proteintech, 55259-1-AP); ANT1/SLC25A4 (Cell Signaling, 51755); SLC25A4 (Proteintech, 30631-1-AP); CEND1 (Cell signaling, 8944); CoraLite® Plus 488-conjugated TOM20 Polyclonal antibody (Proteintech, CL488-11802); Neuron-specific beta -III Tubulin Antibody (RD systems, MAB1195); UCP1(Abcam, ab209483); CS (Abcam, ab129095).



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    a Scheme for the generation of an inducible β-cell-specific TBL1X and TBL1XR1 knockout. b Random fed blood glucose levels over time in iTBL/RβKO ( n = 9) and control ( n = 9) mice on HFD. c Total pancreas insulin content normalized to protein levels in iTBL/RβKO and control mice 4 and 11 weeks after tamoxifen administration. n = 3 for 4w control and iTBL/RβKO mice, n = 6 for 11w control mice, n = 4 for 11w iTBL/RβKO mice. d , e Blood glucose ( d ) and plasma insulin ( e ) levels during an oral glucose tolerance test after 22 weeks of HFD. Corresponding area under the curve in iTBL/RβKO ( n = 8) and control ( n = 9) mice ( d , right). f , g Relative mRNA expression determined by qPCR in pancreatic islets of iTBL/RβKO and control mice of Tbl1x and Tbl1xr1 ( f ) and islet genes ( g ). Control mice Tbl1x , Tbl1xr1 , Ins1 , Ins2 , Nkx6.1 , Slc2a2 , Mafa , Pdx1 , Pax6 , Ucn3 : n = 9, control mice ChgA , Ngn3 , Ldha , <t>Hk1</t> : n = 8, iTBL/RβKO mice Tbl1x , Ngn3 , Ldha , Hk1 : n = 7, iTBL/RβKO mice Tbl1xr1 , Ins1 , Ins2 , Slc2a2 , Mafa n = 6, iTBL/RβKO mice Nkx6.1 , Pdx1 , Pax6 , Ucn3 , ChgA : n = 5. h α/β-cell mass ratio of pancreatic islets from iTBL/RβKO ( n = 4) and control mice ( n = 4) on HFD, 24 weeks after knockout induction. i Representative immunofluorescent staining of insulin + (blue, β-cells) and glucagon + (red, α-cells) cells of paraffin-embedded pancreas from iTBL/RβKO and control mice on HFD, 24 weeks after knockout induction. Each point represents one mouse. Data are represented as mean ± SEM. The following statistical tests were applied: two-sided student’s t test ( d – Area under the curve, f – h ) and 2-way ANOVA with Šidák’s multiple comparison post hoc test ( b – d – time course, e ). Source data are provided as a Source Data file.
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    Image Search Results


    a Scheme for the generation of an inducible β-cell-specific TBL1X and TBL1XR1 knockout. b Random fed blood glucose levels over time in iTBL/RβKO ( n = 9) and control ( n = 9) mice on HFD. c Total pancreas insulin content normalized to protein levels in iTBL/RβKO and control mice 4 and 11 weeks after tamoxifen administration. n = 3 for 4w control and iTBL/RβKO mice, n = 6 for 11w control mice, n = 4 for 11w iTBL/RβKO mice. d , e Blood glucose ( d ) and plasma insulin ( e ) levels during an oral glucose tolerance test after 22 weeks of HFD. Corresponding area under the curve in iTBL/RβKO ( n = 8) and control ( n = 9) mice ( d , right). f , g Relative mRNA expression determined by qPCR in pancreatic islets of iTBL/RβKO and control mice of Tbl1x and Tbl1xr1 ( f ) and islet genes ( g ). Control mice Tbl1x , Tbl1xr1 , Ins1 , Ins2 , Nkx6.1 , Slc2a2 , Mafa , Pdx1 , Pax6 , Ucn3 : n = 9, control mice ChgA , Ngn3 , Ldha , Hk1 : n = 8, iTBL/RβKO mice Tbl1x , Ngn3 , Ldha , Hk1 : n = 7, iTBL/RβKO mice Tbl1xr1 , Ins1 , Ins2 , Slc2a2 , Mafa n = 6, iTBL/RβKO mice Nkx6.1 , Pdx1 , Pax6 , Ucn3 , ChgA : n = 5. h α/β-cell mass ratio of pancreatic islets from iTBL/RβKO ( n = 4) and control mice ( n = 4) on HFD, 24 weeks after knockout induction. i Representative immunofluorescent staining of insulin + (blue, β-cells) and glucagon + (red, α-cells) cells of paraffin-embedded pancreas from iTBL/RβKO and control mice on HFD, 24 weeks after knockout induction. Each point represents one mouse. Data are represented as mean ± SEM. The following statistical tests were applied: two-sided student’s t test ( d – Area under the curve, f – h ) and 2-way ANOVA with Šidák’s multiple comparison post hoc test ( b – d – time course, e ). Source data are provided as a Source Data file.

    Journal: Nature Communications

    Article Title: TBL1X/TBL1XR1 govern β-cell identity through a PAX6-containing gene regulatory network

    doi: 10.1038/s41467-026-72077-5

    Figure Lengend Snippet: a Scheme for the generation of an inducible β-cell-specific TBL1X and TBL1XR1 knockout. b Random fed blood glucose levels over time in iTBL/RβKO ( n = 9) and control ( n = 9) mice on HFD. c Total pancreas insulin content normalized to protein levels in iTBL/RβKO and control mice 4 and 11 weeks after tamoxifen administration. n = 3 for 4w control and iTBL/RβKO mice, n = 6 for 11w control mice, n = 4 for 11w iTBL/RβKO mice. d , e Blood glucose ( d ) and plasma insulin ( e ) levels during an oral glucose tolerance test after 22 weeks of HFD. Corresponding area under the curve in iTBL/RβKO ( n = 8) and control ( n = 9) mice ( d , right). f , g Relative mRNA expression determined by qPCR in pancreatic islets of iTBL/RβKO and control mice of Tbl1x and Tbl1xr1 ( f ) and islet genes ( g ). Control mice Tbl1x , Tbl1xr1 , Ins1 , Ins2 , Nkx6.1 , Slc2a2 , Mafa , Pdx1 , Pax6 , Ucn3 : n = 9, control mice ChgA , Ngn3 , Ldha , Hk1 : n = 8, iTBL/RβKO mice Tbl1x , Ngn3 , Ldha , Hk1 : n = 7, iTBL/RβKO mice Tbl1xr1 , Ins1 , Ins2 , Slc2a2 , Mafa n = 6, iTBL/RβKO mice Nkx6.1 , Pdx1 , Pax6 , Ucn3 , ChgA : n = 5. h α/β-cell mass ratio of pancreatic islets from iTBL/RβKO ( n = 4) and control mice ( n = 4) on HFD, 24 weeks after knockout induction. i Representative immunofluorescent staining of insulin + (blue, β-cells) and glucagon + (red, α-cells) cells of paraffin-embedded pancreas from iTBL/RβKO and control mice on HFD, 24 weeks after knockout induction. Each point represents one mouse. Data are represented as mean ± SEM. The following statistical tests were applied: two-sided student’s t test ( d – Area under the curve, f – h ) and 2-way ANOVA with Šidák’s multiple comparison post hoc test ( b – d – time course, e ). Source data are provided as a Source Data file.

    Article Snippet: The following TaqMan probes were used: Tbp - Mm01277042_m1, Tbl1x - Mm01222202_m1, Tbl1xr1 - Mm01283877_m1, Ins1 - Mm01259683_g1, Ins2 - Mm00731595_gH, Nkx6.1 - Mm00454961_m1, Slc2a2 - Mm00454961_m1, Mafa - Mm00845206_s1, Pdx1 - Mm00435565_m1, Pax6 - Mm00443081_m1, Ucn3 - Mm00453206_s1, ChgA - Mm00514341_m1, Ngn3 - Mm00437606_s1, Ldha - Mm01612132_g1, Hk1 - Mm00439344_m1, TBP - Hs00427620_m1, TBL1X - Hs00959540_m1, TBL1XR1 - Hs00226564_m1.

    Techniques: Knock-Out, Control, Clinical Proteomics, Expressing, Staining, Comparison