Review



imatinib mesilate (glivec  (Novartis)

 
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    Novartis imatinib mesilate (glivec
    Imatinib Mesilate (Glivec, supplied by Novartis, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/glivec/nct05009927-2-0-3?v=Novartis
    Average 90 stars, based on 1 article reviews
    imatinib mesilate (glivec - by Bioz Stars, 2026-06
    90/100 stars

    Images



    Similar Products

    imatinib  (MedChemExpress)
    95
    MedChemExpress imatinib
    Imatinib, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/glivec/pm42035550-57-14-17?v=MedChemExpress
    Average 95 stars, based on 1 article reviews
    imatinib - by Bioz Stars, 2026-06
    95/100 stars
    		  Buy from Supplier
    imatinib mesilate (glivec  (Novartis)
    90
    Novartis imatinib mesilate (glivec
    Imatinib Mesilate (Glivec, supplied by Novartis, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/glivec/nct05009927-2-0-3?v=Novartis
    Average 90 stars, based on 1 article reviews
    imatinib mesilate (glivec - by Bioz Stars, 2026-06
    90/100 stars
    		  Buy from Supplier
    generic imatinib  (Novartis)
    86
    Novartis generic imatinib
    Generic Imatinib, supplied by Novartis, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/glivec/10__1200_slash_op___25___01096-98-22-30?v=Novartis
    Average 86 stars, based on 1 article reviews
    generic imatinib - by Bioz Stars, 2026-06
    86/100 stars
    		  Buy from Supplier
    glivec  (Novartis)
    86
    Novartis glivec
    Glivec, supplied by Novartis, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/glivec/pm42135167-90-14-20?v=Novartis
    Average 86 stars, based on 1 article reviews
    glivec - by Bioz Stars, 2026-06
    86/100 stars
    		  Buy from Supplier
    imatinib rnesylate  (Novartis)
    86
    Novartis imatinib rnesylate
    Imatinib Rnesylate, supplied by Novartis, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/glivec/us12622983-94-22-25?v=Novartis
    Average 86 stars, based on 1 article reviews
    imatinib rnesylate - by Bioz Stars, 2026-06
    86/100 stars
    		  Buy from Supplier
    abl tyrosine kinase inhibitor cgp57148b  (Ciba Geigy)
    86
    Ciba Geigy abl tyrosine kinase inhibitor cgp57148b
    Abl Tyrosine Kinase Inhibitor Cgp57148b, supplied by Ciba Geigy, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/glivec/10__1042_slash_ebc20260003-94-9-3?v=Ciba+Geigy
    Average 86 stars, based on 1 article reviews
    abl tyrosine kinase inhibitor cgp57148b - by Bioz Stars, 2026-06
    86/100 stars
    		  Buy from Supplier
    gleevec  (Novartis)
    86
    Novartis gleevec
    Gleevec, supplied by Novartis, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/glivec/us12617787-322-65-66?v=Novartis
    Average 86 stars, based on 1 article reviews
    gleevec - by Bioz Stars, 2026-06
    86/100 stars
    		  Buy from Supplier
    imatinib  (Novartis)
    86
    Novartis imatinib
    Cresyl violet staining of the CA1 and CA3 regions of the hippocampus (×40 magnification). A : CA1, control. Normal pyramidal neurons with well-organized and densely packed cellular architecture. B : CA3, control. Preserved neuronal morphology and normal pyramidal cell layer organization. C : CA1, ICV-STZ + saline. Reduced neuronal density and early neurodegenerative changes, including shrunken pyramidal neurons and pericellular spaces (arrows). D : CA3, ICV-STZ + saline. Marked neuronal loss, severe disruption of pyramidal layer organization, and presence of pyknotic neurons (arrows). E : CA1, ICV-STZ + <t>imatinib.</t> Increased neuronal count compared to the ICV-STZ group, with partial restoration of pyramidal neuron morphology. F : CA3, ICV-STZ + imatinib. Moderate improvement in neuronal density and morphology, although some degenerative changes persist. G : CA1, ICV-STZ + nilotinib. Increased neuronal density and improved cellular organization, approaching nearnormal morphology. H : CA3, ICV-STZ + nilotinib. Significant restoration of pyramidal layer structure with increased neuronal count and improved morphology. ICV-STZ : intracerebroventricular streptozotocin.
    Imatinib, supplied by Novartis, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/glivec/pmc13172787-59-6-10?v=Novartis
    Average 86 stars, based on 1 article reviews
    imatinib - by Bioz Stars, 2026-06
    86/100 stars
    		  Buy from Supplier

    Image Search Results


    Cresyl violet staining of the CA1 and CA3 regions of the hippocampus (×40 magnification). A : CA1, control. Normal pyramidal neurons with well-organized and densely packed cellular architecture. B : CA3, control. Preserved neuronal morphology and normal pyramidal cell layer organization. C : CA1, ICV-STZ + saline. Reduced neuronal density and early neurodegenerative changes, including shrunken pyramidal neurons and pericellular spaces (arrows). D : CA3, ICV-STZ + saline. Marked neuronal loss, severe disruption of pyramidal layer organization, and presence of pyknotic neurons (arrows). E : CA1, ICV-STZ + imatinib. Increased neuronal count compared to the ICV-STZ group, with partial restoration of pyramidal neuron morphology. F : CA3, ICV-STZ + imatinib. Moderate improvement in neuronal density and morphology, although some degenerative changes persist. G : CA1, ICV-STZ + nilotinib. Increased neuronal density and improved cellular organization, approaching nearnormal morphology. H : CA3, ICV-STZ + nilotinib. Significant restoration of pyramidal layer structure with increased neuronal count and improved morphology. ICV-STZ : intracerebroventricular streptozotocin.

    Journal: Journal of Korean Neurosurgical Society

    Article Title: Comparative Evaluation of Imatinib and Nilotinib in a Streptozotocin-Induced Rat Model of Alzheimer’s Disease : Neuroprotective, Anti-inflammatory, and Cognitive Outcomes

    doi: 10.3340/jkns.2025.0110

    Figure Lengend Snippet: Cresyl violet staining of the CA1 and CA3 regions of the hippocampus (×40 magnification). A : CA1, control. Normal pyramidal neurons with well-organized and densely packed cellular architecture. B : CA3, control. Preserved neuronal morphology and normal pyramidal cell layer organization. C : CA1, ICV-STZ + saline. Reduced neuronal density and early neurodegenerative changes, including shrunken pyramidal neurons and pericellular spaces (arrows). D : CA3, ICV-STZ + saline. Marked neuronal loss, severe disruption of pyramidal layer organization, and presence of pyknotic neurons (arrows). E : CA1, ICV-STZ + imatinib. Increased neuronal count compared to the ICV-STZ group, with partial restoration of pyramidal neuron morphology. F : CA3, ICV-STZ + imatinib. Moderate improvement in neuronal density and morphology, although some degenerative changes persist. G : CA1, ICV-STZ + nilotinib. Increased neuronal density and improved cellular organization, approaching nearnormal morphology. H : CA3, ICV-STZ + nilotinib. Significant restoration of pyramidal layer structure with increased neuronal count and improved morphology. ICV-STZ : intracerebroventricular streptozotocin.

    Article Snippet: Group 2 (n=8) received 60 mg/kg imatinib (Gleevec ® ; Novartis Pharmaceuticals, Basel, Switzerland) daily via oral gavage.

    Techniques: Staining, Control, Saline, Disruption