Review



fsp27  (Bioss)


Bioz Verified Symbol Bioss is a verified supplier
Bioz Manufacturer Symbol Bioss manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 93
      Buy from Supplier

    Structured Review

    Bioss fsp27
    Fsp27, supplied by Bioss, used in various techniques. Bioz Stars score: 93/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/fsp27/product/Bioss
    Average 93 stars, based on 5 article reviews
    fsp27 - by Bioz Stars, 2026-04
    93/100 stars

    Images



    Similar Products

    cidec  (MedChemExpress)
    93
    MedChemExpress cidec
    Cidec, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cidec/product/MedChemExpress
    Average 93 stars, based on 1 article reviews
    cidec - by Bioz Stars, 2026-04
    93/100 stars
    		  Buy from Supplier
    fsp27  (Bioss)
    93
    Bioss fsp27
    Fsp27, supplied by Bioss, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/fsp27/product/Bioss
    Average 93 stars, based on 1 article reviews
    fsp27 - by Bioz Stars, 2026-04
    93/100 stars
    		  Buy from Supplier
    fsp27  (Novus Biologicals)
    95
    Novus Biologicals fsp27
    Figure 1: Depletion of TMEM135 decreases lipid accumulation in the liver of HFD mice and FFA-treated primary hepatocytes and AML12 cells. (AeC) WT and TMEM135KO mice were fed either NCD or HFD for 22 weeks (n ¼ 6 per group). (A) Oil Red O staining of liver tissue section (Original magnification x100). (B) Immunoblots and densitometry for PLIN2, <t>FSP27,</t> and b-actin from the liver tissue of mice. Data represent mean SD, **p < 0.01, *p < 0.05, Two-way ANOVA. (C) Hepatic TG levels. Data represent mean SD, **p < 0.01, Two-way ANOVA. (DeF) Primary hepatocytes were isolated from the livers of WT and TMEM135KO mice and treated with FFA for 12 h. (D) Oil Red O staining and quantification of LD area (Original magnification x40, scale bar 20 mm). More than 100 cells per group in each experiment were measured. Data represent mean SD, ****p < 0.0001, Two-way ANOVA. (E) Immunoblots and densitometry for PLIN2 and b-actin. Data represent mean SD, ****p < 0.0001, ***p < 0.001, Two- way ANOVA. (F) Quantification of TG levels. Data represent mean SD, ****p < 0.0001, Two-way ANOVA. (GeI) sh-Scramble and sh-TMEM135 cells were treated with FFA for 12 h. (G) Oil Red O staining and quantification of LD area (Original magnification x100, scale bar 20 mm). More than 100 cells per group in each experiment were measured. Data represent mean SD, ****p < 0.0001, **p < 0.01, Two-way ANOVA. (H) Immunoblots and densitometry for PLIN2 and b-actin. Data represent mean SD, ****p < 0.0001, Two-way ANOVA. (I) Quantification of TG levels. Data represent mean SD, ****p < 0.0001, **p < 0.01, Two-way ANOVA. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
    Fsp27, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/fsp27/product/Novus Biologicals
    Average 95 stars, based on 1 article reviews
    fsp27 - by Bioz Stars, 2026-04
    95/100 stars
    		  Buy from Supplier
    fsp27 protein  (Ohta s Isan Co Ltd)
    90
    Ohta s Isan Co Ltd fsp27 protein
    Figure 1: Depletion of TMEM135 decreases lipid accumulation in the liver of HFD mice and FFA-treated primary hepatocytes and AML12 cells. (AeC) WT and TMEM135KO mice were fed either NCD or HFD for 22 weeks (n ¼ 6 per group). (A) Oil Red O staining of liver tissue section (Original magnification x100). (B) Immunoblots and densitometry for PLIN2, <t>FSP27,</t> and b-actin from the liver tissue of mice. Data represent mean SD, **p < 0.01, *p < 0.05, Two-way ANOVA. (C) Hepatic TG levels. Data represent mean SD, **p < 0.01, Two-way ANOVA. (DeF) Primary hepatocytes were isolated from the livers of WT and TMEM135KO mice and treated with FFA for 12 h. (D) Oil Red O staining and quantification of LD area (Original magnification x40, scale bar 20 mm). More than 100 cells per group in each experiment were measured. Data represent mean SD, ****p < 0.0001, Two-way ANOVA. (E) Immunoblots and densitometry for PLIN2 and b-actin. Data represent mean SD, ****p < 0.0001, ***p < 0.001, Two- way ANOVA. (F) Quantification of TG levels. Data represent mean SD, ****p < 0.0001, Two-way ANOVA. (GeI) sh-Scramble and sh-TMEM135 cells were treated with FFA for 12 h. (G) Oil Red O staining and quantification of LD area (Original magnification x100, scale bar 20 mm). More than 100 cells per group in each experiment were measured. Data represent mean SD, ****p < 0.0001, **p < 0.01, Two-way ANOVA. (H) Immunoblots and densitometry for PLIN2 and b-actin. Data represent mean SD, ****p < 0.0001, Two-way ANOVA. (I) Quantification of TG levels. Data represent mean SD, ****p < 0.0001, **p < 0.01, Two-way ANOVA. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
    Fsp27 Protein, supplied by Ohta s Isan Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/fsp27 protein/product/Ohta s Isan Co Ltd
    Average 90 stars, based on 1 article reviews
    fsp27 protein - by Bioz Stars, 2026-04
    90/100 stars
    		  Buy from Supplier
    fsp27 fl/fl mice  (Jackson Laboratory)
    90
    Jackson Laboratory fsp27 fl/fl mice
    Figure 1: Depletion of TMEM135 decreases lipid accumulation in the liver of HFD mice and FFA-treated primary hepatocytes and AML12 cells. (AeC) WT and TMEM135KO mice were fed either NCD or HFD for 22 weeks (n ¼ 6 per group). (A) Oil Red O staining of liver tissue section (Original magnification x100). (B) Immunoblots and densitometry for PLIN2, <t>FSP27,</t> and b-actin from the liver tissue of mice. Data represent mean SD, **p < 0.01, *p < 0.05, Two-way ANOVA. (C) Hepatic TG levels. Data represent mean SD, **p < 0.01, Two-way ANOVA. (DeF) Primary hepatocytes were isolated from the livers of WT and TMEM135KO mice and treated with FFA for 12 h. (D) Oil Red O staining and quantification of LD area (Original magnification x40, scale bar 20 mm). More than 100 cells per group in each experiment were measured. Data represent mean SD, ****p < 0.0001, Two-way ANOVA. (E) Immunoblots and densitometry for PLIN2 and b-actin. Data represent mean SD, ****p < 0.0001, ***p < 0.001, Two- way ANOVA. (F) Quantification of TG levels. Data represent mean SD, ****p < 0.0001, Two-way ANOVA. (GeI) sh-Scramble and sh-TMEM135 cells were treated with FFA for 12 h. (G) Oil Red O staining and quantification of LD area (Original magnification x100, scale bar 20 mm). More than 100 cells per group in each experiment were measured. Data represent mean SD, ****p < 0.0001, **p < 0.01, Two-way ANOVA. (H) Immunoblots and densitometry for PLIN2 and b-actin. Data represent mean SD, ****p < 0.0001, Two-way ANOVA. (I) Quantification of TG levels. Data represent mean SD, ****p < 0.0001, **p < 0.01, Two-way ANOVA. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
    Fsp27 Fl/Fl Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/fsp27 fl/fl mice/product/Jackson Laboratory
    Average 90 stars, based on 1 article reviews
    fsp27 fl/fl mice - by Bioz Stars, 2026-04
    90/100 stars
    		  Buy from Supplier
    anti-fsp27 pa1-46128  (Thermo Fisher)
    90
    Thermo Fisher anti-fsp27 pa1-46128
    Figure 1: Depletion of TMEM135 decreases lipid accumulation in the liver of HFD mice and FFA-treated primary hepatocytes and AML12 cells. (AeC) WT and TMEM135KO mice were fed either NCD or HFD for 22 weeks (n ¼ 6 per group). (A) Oil Red O staining of liver tissue section (Original magnification x100). (B) Immunoblots and densitometry for PLIN2, <t>FSP27,</t> and b-actin from the liver tissue of mice. Data represent mean SD, **p < 0.01, *p < 0.05, Two-way ANOVA. (C) Hepatic TG levels. Data represent mean SD, **p < 0.01, Two-way ANOVA. (DeF) Primary hepatocytes were isolated from the livers of WT and TMEM135KO mice and treated with FFA for 12 h. (D) Oil Red O staining and quantification of LD area (Original magnification x40, scale bar 20 mm). More than 100 cells per group in each experiment were measured. Data represent mean SD, ****p < 0.0001, Two-way ANOVA. (E) Immunoblots and densitometry for PLIN2 and b-actin. Data represent mean SD, ****p < 0.0001, ***p < 0.001, Two- way ANOVA. (F) Quantification of TG levels. Data represent mean SD, ****p < 0.0001, Two-way ANOVA. (GeI) sh-Scramble and sh-TMEM135 cells were treated with FFA for 12 h. (G) Oil Red O staining and quantification of LD area (Original magnification x100, scale bar 20 mm). More than 100 cells per group in each experiment were measured. Data represent mean SD, ****p < 0.0001, **p < 0.01, Two-way ANOVA. (H) Immunoblots and densitometry for PLIN2 and b-actin. Data represent mean SD, ****p < 0.0001, Two-way ANOVA. (I) Quantification of TG levels. Data represent mean SD, ****p < 0.0001, **p < 0.01, Two-way ANOVA. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
    Anti Fsp27 Pa1 46128, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti-fsp27 pa1-46128/product/Thermo Fisher
    Average 90 stars, based on 1 article reviews
    anti-fsp27 pa1-46128 - by Bioz Stars, 2026-04
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Figure 1: Depletion of TMEM135 decreases lipid accumulation in the liver of HFD mice and FFA-treated primary hepatocytes and AML12 cells. (AeC) WT and TMEM135KO mice were fed either NCD or HFD for 22 weeks (n ¼ 6 per group). (A) Oil Red O staining of liver tissue section (Original magnification x100). (B) Immunoblots and densitometry for PLIN2, FSP27, and b-actin from the liver tissue of mice. Data represent mean SD, **p < 0.01, *p < 0.05, Two-way ANOVA. (C) Hepatic TG levels. Data represent mean SD, **p < 0.01, Two-way ANOVA. (DeF) Primary hepatocytes were isolated from the livers of WT and TMEM135KO mice and treated with FFA for 12 h. (D) Oil Red O staining and quantification of LD area (Original magnification x40, scale bar 20 mm). More than 100 cells per group in each experiment were measured. Data represent mean SD, ****p < 0.0001, Two-way ANOVA. (E) Immunoblots and densitometry for PLIN2 and b-actin. Data represent mean SD, ****p < 0.0001, ***p < 0.001, Two- way ANOVA. (F) Quantification of TG levels. Data represent mean SD, ****p < 0.0001, Two-way ANOVA. (GeI) sh-Scramble and sh-TMEM135 cells were treated with FFA for 12 h. (G) Oil Red O staining and quantification of LD area (Original magnification x100, scale bar 20 mm). More than 100 cells per group in each experiment were measured. Data represent mean SD, ****p < 0.0001, **p < 0.01, Two-way ANOVA. (H) Immunoblots and densitometry for PLIN2 and b-actin. Data represent mean SD, ****p < 0.0001, Two-way ANOVA. (I) Quantification of TG levels. Data represent mean SD, ****p < 0.0001, **p < 0.01, Two-way ANOVA. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

    Journal: Molecular metabolism

    Article Title: TMEM135 deficiency improves hepatic steatosis by suppressing CD36 in a SIRT1-dependent manner.

    doi: 10.1016/j.molmet.2024.102080

    Figure Lengend Snippet: Figure 1: Depletion of TMEM135 decreases lipid accumulation in the liver of HFD mice and FFA-treated primary hepatocytes and AML12 cells. (AeC) WT and TMEM135KO mice were fed either NCD or HFD for 22 weeks (n ¼ 6 per group). (A) Oil Red O staining of liver tissue section (Original magnification x100). (B) Immunoblots and densitometry for PLIN2, FSP27, and b-actin from the liver tissue of mice. Data represent mean SD, **p < 0.01, *p < 0.05, Two-way ANOVA. (C) Hepatic TG levels. Data represent mean SD, **p < 0.01, Two-way ANOVA. (DeF) Primary hepatocytes were isolated from the livers of WT and TMEM135KO mice and treated with FFA for 12 h. (D) Oil Red O staining and quantification of LD area (Original magnification x40, scale bar 20 mm). More than 100 cells per group in each experiment were measured. Data represent mean SD, ****p < 0.0001, Two-way ANOVA. (E) Immunoblots and densitometry for PLIN2 and b-actin. Data represent mean SD, ****p < 0.0001, ***p < 0.001, Two- way ANOVA. (F) Quantification of TG levels. Data represent mean SD, ****p < 0.0001, Two-way ANOVA. (GeI) sh-Scramble and sh-TMEM135 cells were treated with FFA for 12 h. (G) Oil Red O staining and quantification of LD area (Original magnification x100, scale bar 20 mm). More than 100 cells per group in each experiment were measured. Data represent mean SD, ****p < 0.0001, **p < 0.01, Two-way ANOVA. (H) Immunoblots and densitometry for PLIN2 and b-actin. Data represent mean SD, ****p < 0.0001, Two-way ANOVA. (I) Quantification of TG levels. Data represent mean SD, ****p < 0.0001, **p < 0.01, Two-way ANOVA. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

    Article Snippet: CD36 antibody (#NB400-144) and FSP27 (#NB100-430) were bought from Novus Biological (Minneapolis, MN, USA).

    Techniques: Staining, Western Blot, Isolation