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fluasterone  (MedChemExpress)


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    MedChemExpress fluasterone
    Fluasterone, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/fluasterone/product/MedChemExpress
    Average 94 stars, based on 1 article reviews
    fluasterone - by Bioz Stars, 2026-02
    94/100 stars

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    Image Search Results


    The structure of fluasterone with atom numbering.

    Journal:

    Article Title: Identification of [ 14 C]Fluasterone Metabolites in Urine and Feces Collected from Dogs after Subcutaneous and Oral Administration of [ 14 C]Fluasterone

    doi: 10.1124/dmd.108.023614

    Figure Lengend Snippet: The structure of fluasterone with atom numbering.

    Article Snippet: Radiolabeled [4- 14 C]fluasterone (lot 9676-29-07 from Midwest Research Institute, Kansas, MO) had a radiochemical purity of approximately 97% and specific activity of 58.3 mCi/mmol.

    Techniques:

    Mean (S.D.) percentage cumulative recovery of total radioactivity postdose after subcutaneous and oral administration of [ 14 C ] fluasterone in male dogs

    Journal:

    Article Title: Identification of [ 14 C]Fluasterone Metabolites in Urine and Feces Collected from Dogs after Subcutaneous and Oral Administration of [ 14 C]Fluasterone

    doi: 10.1124/dmd.108.023614

    Figure Lengend Snippet: Mean (S.D.) percentage cumulative recovery of total radioactivity postdose after subcutaneous and oral administration of [ 14 C ] fluasterone in male dogs

    Article Snippet: Radiolabeled [4- 14 C]fluasterone (lot 9676-29-07 from Midwest Research Institute, Kansas, MO) had a radiochemical purity of approximately 97% and specific activity of 58.3 mCi/mmol.

    Techniques: Radioactivity

    HPLC/LSS profiles of nonenzyme- and enzyme-treated 8- to 24-h urine collected after subcutaneous administration of [14C]fluasterone at 1 mg/kg.

    Journal:

    Article Title: Identification of [ 14 C]Fluasterone Metabolites in Urine and Feces Collected from Dogs after Subcutaneous and Oral Administration of [ 14 C]Fluasterone

    doi: 10.1124/dmd.108.023614

    Figure Lengend Snippet: HPLC/LSS profiles of nonenzyme- and enzyme-treated 8- to 24-h urine collected after subcutaneous administration of [14C]fluasterone at 1 mg/kg.

    Article Snippet: Radiolabeled [4- 14 C]fluasterone (lot 9676-29-07 from Midwest Research Institute, Kansas, MO) had a radiochemical purity of approximately 97% and specific activity of 58.3 mCi/mmol.

    Techniques:

    HPLC/LSS profiles of 8- to 24-h urine collected from two dogs after oral administration of [14C]fluasterone at 15 mg/kg.

    Journal:

    Article Title: Identification of [ 14 C]Fluasterone Metabolites in Urine and Feces Collected from Dogs after Subcutaneous and Oral Administration of [ 14 C]Fluasterone

    doi: 10.1124/dmd.108.023614

    Figure Lengend Snippet: HPLC/LSS profiles of 8- to 24-h urine collected from two dogs after oral administration of [14C]fluasterone at 15 mg/kg.

    Article Snippet: Radiolabeled [4- 14 C]fluasterone (lot 9676-29-07 from Midwest Research Institute, Kansas, MO) had a radiochemical purity of approximately 97% and specific activity of 58.3 mCi/mmol.

    Techniques:

    Top, HPLC/LSS profiles using HPLC Method 1 of methanol extracts of 8- to 24- and 24- to 48-h feces collected from a single dog after oral administration of [14C]fluasterone at 15 mg/kg and 24- to 48-h feces collected from a dog after subcutaneous administration of [14C]fluasterone at 1 mg/kg. Bottom, HPLC/LSS profiles using HPLC Method 2 of the same extracts shown in A.

    Journal:

    Article Title: Identification of [ 14 C]Fluasterone Metabolites in Urine and Feces Collected from Dogs after Subcutaneous and Oral Administration of [ 14 C]Fluasterone

    doi: 10.1124/dmd.108.023614

    Figure Lengend Snippet: Top, HPLC/LSS profiles using HPLC Method 1 of methanol extracts of 8- to 24- and 24- to 48-h feces collected from a single dog after oral administration of [14C]fluasterone at 15 mg/kg and 24- to 48-h feces collected from a dog after subcutaneous administration of [14C]fluasterone at 1 mg/kg. Bottom, HPLC/LSS profiles using HPLC Method 2 of the same extracts shown in A.

    Article Snippet: Radiolabeled [4- 14 C]fluasterone (lot 9676-29-07 from Midwest Research Institute, Kansas, MO) had a radiochemical purity of approximately 97% and specific activity of 58.3 mCi/mmol.

    Techniques:

    HPLC radiochromatographic profile recorded during LC/MS analysis of nonenzyme-treated urine collected from a single dog between 8 and 24 h after a subcutaneous dose of [14C]fluasterone at 1 mg/kg.

    Journal:

    Article Title: Identification of [ 14 C]Fluasterone Metabolites in Urine and Feces Collected from Dogs after Subcutaneous and Oral Administration of [ 14 C]Fluasterone

    doi: 10.1124/dmd.108.023614

    Figure Lengend Snippet: HPLC radiochromatographic profile recorded during LC/MS analysis of nonenzyme-treated urine collected from a single dog between 8 and 24 h after a subcutaneous dose of [14C]fluasterone at 1 mg/kg.

    Article Snippet: Radiolabeled [4- 14 C]fluasterone (lot 9676-29-07 from Midwest Research Institute, Kansas, MO) had a radiochemical purity of approximately 97% and specific activity of 58.3 mCi/mmol.

    Techniques: Liquid Chromatography with Mass Spectroscopy

    HPLC radiochromatographic profile recorded during LC/MS analysis of glucuronidase-treated urine collected from a single dog between 8 and 24 h after a subcutaneous dose of [14C]fluasterone at 1 mg/kg.

    Journal:

    Article Title: Identification of [ 14 C]Fluasterone Metabolites in Urine and Feces Collected from Dogs after Subcutaneous and Oral Administration of [ 14 C]Fluasterone

    doi: 10.1124/dmd.108.023614

    Figure Lengend Snippet: HPLC radiochromatographic profile recorded during LC/MS analysis of glucuronidase-treated urine collected from a single dog between 8 and 24 h after a subcutaneous dose of [14C]fluasterone at 1 mg/kg.

    Article Snippet: Radiolabeled [4- 14 C]fluasterone (lot 9676-29-07 from Midwest Research Institute, Kansas, MO) had a radiochemical purity of approximately 97% and specific activity of 58.3 mCi/mmol.

    Techniques: Liquid Chromatography with Mass Spectroscopy

    HPLC radiochromatographic profile recorded during LC/MS analysis of a methanol extract of feces collected between 8 and 24 h after oral dosing with [14C]fluasterone at 15 mg/kg.

    Journal:

    Article Title: Identification of [ 14 C]Fluasterone Metabolites in Urine and Feces Collected from Dogs after Subcutaneous and Oral Administration of [ 14 C]Fluasterone

    doi: 10.1124/dmd.108.023614

    Figure Lengend Snippet: HPLC radiochromatographic profile recorded during LC/MS analysis of a methanol extract of feces collected between 8 and 24 h after oral dosing with [14C]fluasterone at 15 mg/kg.

    Article Snippet: Radiolabeled [4- 14 C]fluasterone (lot 9676-29-07 from Midwest Research Institute, Kansas, MO) had a radiochemical purity of approximately 97% and specific activity of 58.3 mCi/mmol.

    Techniques: Liquid Chromatography with Mass Spectroscopy

    Proton NMR spectra of isolated urinary metabolite eluting at approximately 21.6 min in nonenzyme-treated urine collected between 8 and 24 h after oral dosing with [14C]fluasterone at 15 mg/kg (A), 7-α-hydroxyfluasterone (B), 7-β-hydroxyfluasterone (C), 7-β-hydroxy-17-α-dihydrofluasterone (D), and 7-β-hydroxy-17-β-dihydrofluasterone (E).

    Journal:

    Article Title: Identification of [ 14 C]Fluasterone Metabolites in Urine and Feces Collected from Dogs after Subcutaneous and Oral Administration of [ 14 C]Fluasterone

    doi: 10.1124/dmd.108.023614

    Figure Lengend Snippet: Proton NMR spectra of isolated urinary metabolite eluting at approximately 21.6 min in nonenzyme-treated urine collected between 8 and 24 h after oral dosing with [14C]fluasterone at 15 mg/kg (A), 7-α-hydroxyfluasterone (B), 7-β-hydroxyfluasterone (C), 7-β-hydroxy-17-α-dihydrofluasterone (D), and 7-β-hydroxy-17-β-dihydrofluasterone (E).

    Article Snippet: Radiolabeled [4- 14 C]fluasterone (lot 9676-29-07 from Midwest Research Institute, Kansas, MO) had a radiochemical purity of approximately 97% and specific activity of 58.3 mCi/mmol.

    Techniques: Proton NMR, Isolation

    Proton-carbon correlation spectrum of isolated urinary metabolite eluting at approximately 21.6 min in nonenzyme-treated urine collected between 8 and 24 h after oral dosing with [14C]fluasterone at 15 mg/kg. The correlations for H4 through C4 and H6 through C6 are labeled.

    Journal:

    Article Title: Identification of [ 14 C]Fluasterone Metabolites in Urine and Feces Collected from Dogs after Subcutaneous and Oral Administration of [ 14 C]Fluasterone

    doi: 10.1124/dmd.108.023614

    Figure Lengend Snippet: Proton-carbon correlation spectrum of isolated urinary metabolite eluting at approximately 21.6 min in nonenzyme-treated urine collected between 8 and 24 h after oral dosing with [14C]fluasterone at 15 mg/kg. The correlations for H4 through C4 and H6 through C6 are labeled.

    Article Snippet: Radiolabeled [4- 14 C]fluasterone (lot 9676-29-07 from Midwest Research Institute, Kansas, MO) had a radiochemical purity of approximately 97% and specific activity of 58.3 mCi/mmol.

    Techniques: Isolation, Labeling

    Proton-proton correlation spectrum of isolated urinary metabolite eluting at approximately 21.6 in nonenzyme-treated urine collected between 8 and 24 h after oral dosing with [14C]fluasterone at 15 mg/kg. The correlations for H3 to H4 are labeled.

    Journal:

    Article Title: Identification of [ 14 C]Fluasterone Metabolites in Urine and Feces Collected from Dogs after Subcutaneous and Oral Administration of [ 14 C]Fluasterone

    doi: 10.1124/dmd.108.023614

    Figure Lengend Snippet: Proton-proton correlation spectrum of isolated urinary metabolite eluting at approximately 21.6 in nonenzyme-treated urine collected between 8 and 24 h after oral dosing with [14C]fluasterone at 15 mg/kg. The correlations for H3 to H4 are labeled.

    Article Snippet: Radiolabeled [4- 14 C]fluasterone (lot 9676-29-07 from Midwest Research Institute, Kansas, MO) had a radiochemical purity of approximately 97% and specific activity of 58.3 mCi/mmol.

    Techniques: Isolation, Labeling

    Proposed metabolic scheme of fluasterone.

    Journal:

    Article Title: Identification of [ 14 C]Fluasterone Metabolites in Urine and Feces Collected from Dogs after Subcutaneous and Oral Administration of [ 14 C]Fluasterone

    doi: 10.1124/dmd.108.023614

    Figure Lengend Snippet: Proposed metabolic scheme of fluasterone.

    Article Snippet: Radiolabeled [4- 14 C]fluasterone (lot 9676-29-07 from Midwest Research Institute, Kansas, MO) had a radiochemical purity of approximately 97% and specific activity of 58.3 mCi/mmol.

    Techniques: