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rabbit anti fkbp5  (Proteintech)


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    Structured Review

    Proteintech rabbit anti fkbp5
    Rabbit Anti Fkbp5, supplied by Proteintech, used in various techniques. Bioz Stars score: 94/100, based on 38 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/fkbp5/FKBP5+Antibody/10__1038_slash_s41590___026___02472___z-599-44-49
    Average 94 stars, based on 38 article reviews
    rabbit anti fkbp5 - by Bioz Stars, 2026-09
    94/100 stars

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    Related Articles

    Incubation:

    Article Title: Xiaoyaosan alleviates chronic psychological stress-induced TH17/Treg imbalance via modulation of the FKBP5/NF-κB axis.
    Article Snippet: 20 Ethnopharmacological relevance: Xiaoyaosan (XYS), a classical herbal formulation indicated 21 for “depression syndrome”, can improve chronic stress-related mood disorders and immune 22 disorders through multi-target modulation of inflammatory mediators, although its precise 23 mechanism in regulating Th17/Treg balance remains to be clarified.. 24 Aim of the study: This study aims to elucidate the regulatory impact of XYS on the peripheral 25 Th17/Treg immunological imbalance generated by chronic psychological stress through 26 modulation of the FKBP5/NF-κB signaling pathway, thereby establishing a mechanistic 27 foundation for developing innovative interventions with dual stress-adaptogenic and 28 Jo urn al Pr e-p roo f

    Article Title: FKBP5-CCL5 interaction promotes neuroinflammation and neuronal apoptosis in ischemic stroke by regulating the MAPK pathway and enhancing NET formation
    Article Snippet: 20 μg of protein in each sample was separated using SDS-PAGE and subsequently transferred to PVDF membranes (Millipore, Temecula, CA, USA). .. Membranes were blocked with non-specific blocking solution and then incubated overnight at 4°C with primary antibodies: FKBP5 (14155-1-AP, Proteintech), CCL5 (AF5151, Affinity), ERK (BF8004, Affinity), p-ERK (AF1015, Affinity), P38 (14064-1-AP, Proteintech), p-P38 (28796-1-AP, Proteintech), p-JNK (60666-1-Ig, Proteintech), JNK (66210-1-IG, Proteintech), CD206 (60143-1-IG, Proteintech), and GAPDH (60004-1-Ig, Proteintech). .. After washing in TBST, membranes were incubated with HRP-conjugated secondary antibodies (1:5000, Cell Signaling Technology, USA) at room temperature for 1 hour.

    Article Title: Inhibition of the NFATc2/FKBP5 axis alleviates microglial neuroinflammation by regulating arachidonic acid metabolism in Parkinson's disease.
    Article Snippet: Microglia-induced neuroinflammation is among the core pathological hallmarks of Parkinson’s disease (PD).. FKBP5, which has been implicated in stress-related disorders, is recognized as a key regulator of inflammatory responses.. However, the role and mechanism of FKBP5 in PD remain unclear.

    Article Title: A new tissue-agnostic microfluidic device to model physiology and disease: the lattice platform.
    Article Snippet: rsc.li/loc A new tissue-agnostic microfluidic device to model physiology and disease: the lattice platform† Hannes Campo, a Didi Zha, Pawat Pattarawat, Jose Colina, Delong Zhang, c Alina Murphy, Julia Yoon, Angela Russo, Hunter B. Rogers, Hoi Chang Lee, Jiyang Zhang, Katy Trotter, Sarah Wagner, Asia Ingram, a Mary Ellen Pavone, Sara Fernandez Dunne, Christina E. Boots, Margrit Urbanek, Shuo Xiao, Joanna E. Burdette, b Teresa K. Woodruff* and J. Julie Kim*

    Article Title: Single-cell sequencing of facial adipose tissue unveils FKBP5 as a therapeutic target for facial infiltrating lipomatosis
    Article Snippet: .. For the purpose of immunohistochemistry, slices were treated with primary antibodies directed against FKBP5 (Proteintech, USA, 67874-1-Ig), and incubated overnight at 4 °C. ..

    Article Title: Unveiling potential diagnostic biomarkers for rheumatoid arthritis through integrated gene expression analysis
    Article Snippet: .. Subsequently, they were incubated with the primary antibodies against PCDH9 (Abcam, ab233710), GABARAPL1 (Abcam, ab109364), FKBP5 (Proteintech, 14155-1-AP), SLAMF8 (Novus Biologicals, AF1907), and GAPDH (Proteintech, 10494-1-AP) for an overnight period at 4°C. .. Membranes were incubated with the primary antibody for one hour at room temperature, and then treated with horseradish peroxidase-linked secondary antibody (Proteintech, 1:5000).

    Blocking Assay:

    Article Title: FKBP5-CCL5 interaction promotes neuroinflammation and neuronal apoptosis in ischemic stroke by regulating the MAPK pathway and enhancing NET formation
    Article Snippet: 20 μg of protein in each sample was separated using SDS-PAGE and subsequently transferred to PVDF membranes (Millipore, Temecula, CA, USA). .. Membranes were blocked with non-specific blocking solution and then incubated overnight at 4°C with primary antibodies: FKBP5 (14155-1-AP, Proteintech), CCL5 (AF5151, Affinity), ERK (BF8004, Affinity), p-ERK (AF1015, Affinity), P38 (14064-1-AP, Proteintech), p-P38 (28796-1-AP, Proteintech), p-JNK (60666-1-Ig, Proteintech), JNK (66210-1-IG, Proteintech), CD206 (60143-1-IG, Proteintech), and GAPDH (60004-1-Ig, Proteintech). .. After washing in TBST, membranes were incubated with HRP-conjugated secondary antibodies (1:5000, Cell Signaling Technology, USA) at room temperature for 1 hour.

    Immunohistochemistry:

    Article Title: FKBP5 promotes osteogenic differentiation of mesenchymal stem cells through type-I interferon pathway Inhibition
    Article Snippet: According to the direction, the sections were dyed in hematoxylin for 1 min, washed with 70% alcohol containing 1% HCl for 5 s and stained with eosin for 1 min. Masson staining was performed in the light of Masson’s trichrome staining kit (Solarbio, China). .. Following the instruction provided in the immunohistochemistry (IHC) kit (CWBIO, China), IHC stain was conducted adopting FKBP5 (Proteintech, 14155-1-AP, 1:100) and RUNX2 (Proteintech, 20700-1-AP, 1:100) antibodies. ..

    Article Title: FKBP5 promotes osteogenic differentiation of mesenchymal stem cells through type-I interferon pathway Inhibition.
    Article Snippet: According to the direction, the sections were dyed in hematoxylin for 1 min, washed with 70% alcohol containing 1% HCl for 5 s and stained with eosin for 1 min. Masson staining was performed in the light of Masson’s trichrome staining kit (Solarbio, China). .. Following the instruction provided in the immunohistochemistry (IHC) kit (CWBIO, China), IHC stain was conducted adopting FKBP5 (Proteintech, 14155- 1-AP, 1:100) and RUNX2 (Proteintech, 20700-1-AP, 1:100) antibodies. ..

    Article Title: Single-cell sequencing of facial adipose tissue unveils FKBP5 as a therapeutic target for facial infiltrating lipomatosis
    Article Snippet: .. For the purpose of immunohistochemistry, slices were treated with primary antibodies directed against FKBP5 (Proteintech, USA, 67874-1-Ig), and incubated overnight at 4 °C. ..

    Staining:

    Article Title: FKBP5 promotes osteogenic differentiation of mesenchymal stem cells through type-I interferon pathway Inhibition
    Article Snippet: According to the direction, the sections were dyed in hematoxylin for 1 min, washed with 70% alcohol containing 1% HCl for 5 s and stained with eosin for 1 min. Masson staining was performed in the light of Masson’s trichrome staining kit (Solarbio, China). .. Following the instruction provided in the immunohistochemistry (IHC) kit (CWBIO, China), IHC stain was conducted adopting FKBP5 (Proteintech, 14155-1-AP, 1:100) and RUNX2 (Proteintech, 20700-1-AP, 1:100) antibodies. ..

    Article Title: FKBP5 promotes osteogenic differentiation of mesenchymal stem cells through type-I interferon pathway Inhibition.
    Article Snippet: According to the direction, the sections were dyed in hematoxylin for 1 min, washed with 70% alcohol containing 1% HCl for 5 s and stained with eosin for 1 min. Masson staining was performed in the light of Masson’s trichrome staining kit (Solarbio, China). .. Following the instruction provided in the immunohistochemistry (IHC) kit (CWBIO, China), IHC stain was conducted adopting FKBP5 (Proteintech, 14155- 1-AP, 1:100) and RUNX2 (Proteintech, 20700-1-AP, 1:100) antibodies. ..



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    Proteintech fkbp5
    Development and validation of the RA diagnostic columnar line graph model. (A) Columnar line graphs used to predict RA incidence. (B) ROC curve analysis to evaluate the clinical utility of the columnar line graph model. (C) DCA curve analysis to assess the clinical utility of the columnar line graph model. (D) Box plot illustrating the expression levels of GABARAPL1, <t>FKBP5,</t> MREG, PCDH9, and SLAMF8.
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    Image Search Results


    Development and validation of the RA diagnostic columnar line graph model. (A) Columnar line graphs used to predict RA incidence. (B) ROC curve analysis to evaluate the clinical utility of the columnar line graph model. (C) DCA curve analysis to assess the clinical utility of the columnar line graph model. (D) Box plot illustrating the expression levels of GABARAPL1, FKBP5, MREG, PCDH9, and SLAMF8.

    Journal: Frontiers in Immunology

    Article Title: Unveiling potential diagnostic biomarkers for rheumatoid arthritis through integrated gene expression analysis

    doi: 10.3389/fimmu.2026.1645257

    Figure Lengend Snippet: Development and validation of the RA diagnostic columnar line graph model. (A) Columnar line graphs used to predict RA incidence. (B) ROC curve analysis to evaluate the clinical utility of the columnar line graph model. (C) DCA curve analysis to assess the clinical utility of the columnar line graph model. (D) Box plot illustrating the expression levels of GABARAPL1, FKBP5, MREG, PCDH9, and SLAMF8.

    Article Snippet: Subsequently, they were incubated with the primary antibodies against PCDH9 (Abcam, ab233710), GABARAPL1 (Abcam, ab109364), FKBP5 (Proteintech, 14155-1-AP), SLAMF8 (Novus Biologicals, AF1907), and GAPDH (Proteintech, 10494-1-AP) for an overnight period at 4°C.

    Techniques: Biomarker Discovery, Diagnostic Assay, Expressing

    Analysis of hub gene expression in synovial tissues from RA patients. (A) Representative MRI scans illustrating synovial thickening. (B) H&E staining of synovial tissue in trauma control (TC) and RA samples (n = 3). (C) Comparative analysis of mRNA expression levels for GABARAPL1, FKBP5, MREG, PCDH9, and SLAMF8 in TC and RA samples (n = 9). (D) Quantitative assessment of protein concentrations for GABARAPL1, FKBP5, PCDH9, and SLAMF8 in TC and RA samples (n = 3, the samples derive from the same experiment and that gels/blots were processed in parallel. original blots/gels are presented in <xref ref-type=Supplementary Figure 1 ). (E) IF staining results showed protein expression of GABARAPL1, FKBP5, PCDH9, and SLAMF8 in TC and RA samples, visualized with DAPI (blue) and specific antibodies (green) (n = 3). The means ± SD are used to represent the data, while ns (not significant), * P < 0.05, ** P < 0.01, and * P < 0.001 indicate significance levels. " width="100%" height="100%">

    Journal: Frontiers in Immunology

    Article Title: Unveiling potential diagnostic biomarkers for rheumatoid arthritis through integrated gene expression analysis

    doi: 10.3389/fimmu.2026.1645257

    Figure Lengend Snippet: Analysis of hub gene expression in synovial tissues from RA patients. (A) Representative MRI scans illustrating synovial thickening. (B) H&E staining of synovial tissue in trauma control (TC) and RA samples (n = 3). (C) Comparative analysis of mRNA expression levels for GABARAPL1, FKBP5, MREG, PCDH9, and SLAMF8 in TC and RA samples (n = 9). (D) Quantitative assessment of protein concentrations for GABARAPL1, FKBP5, PCDH9, and SLAMF8 in TC and RA samples (n = 3, the samples derive from the same experiment and that gels/blots were processed in parallel. original blots/gels are presented in Supplementary Figure 1 ). (E) IF staining results showed protein expression of GABARAPL1, FKBP5, PCDH9, and SLAMF8 in TC and RA samples, visualized with DAPI (blue) and specific antibodies (green) (n = 3). The means ± SD are used to represent the data, while ns (not significant), * P < 0.05, ** P < 0.01, and * P < 0.001 indicate significance levels.

    Article Snippet: Subsequently, they were incubated with the primary antibodies against PCDH9 (Abcam, ab233710), GABARAPL1 (Abcam, ab109364), FKBP5 (Proteintech, 14155-1-AP), SLAMF8 (Novus Biologicals, AF1907), and GAPDH (Proteintech, 10494-1-AP) for an overnight period at 4°C.

    Techniques: Gene Expression, Staining, Control, Expressing

    Correlation between candidate gene expression and inflammatory indices in the RA cohort. Scatter plots show the associations between PCR-measured expression levels of the candidate genes (GABARAPL1, FKBP5, PCDH9, and SLAMF8) and serum inflammatory markers (ESR and CRP) within RA patients only (n = 9). Spearman’s rank correlation was used to estimate the correlation coefficient ( R ), with p values adjusted for multiple testing using the Benjamini–Hochberg false discovery rate (FDR).

    Journal: Frontiers in Immunology

    Article Title: Unveiling potential diagnostic biomarkers for rheumatoid arthritis through integrated gene expression analysis

    doi: 10.3389/fimmu.2026.1645257

    Figure Lengend Snippet: Correlation between candidate gene expression and inflammatory indices in the RA cohort. Scatter plots show the associations between PCR-measured expression levels of the candidate genes (GABARAPL1, FKBP5, PCDH9, and SLAMF8) and serum inflammatory markers (ESR and CRP) within RA patients only (n = 9). Spearman’s rank correlation was used to estimate the correlation coefficient ( R ), with p values adjusted for multiple testing using the Benjamini–Hochberg false discovery rate (FDR).

    Article Snippet: Subsequently, they were incubated with the primary antibodies against PCDH9 (Abcam, ab233710), GABARAPL1 (Abcam, ab109364), FKBP5 (Proteintech, 14155-1-AP), SLAMF8 (Novus Biologicals, AF1907), and GAPDH (Proteintech, 10494-1-AP) for an overnight period at 4°C.

    Techniques: Gene Expression, Expressing