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fer 1  (MedChemExpress)


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    Structured Review

    MedChemExpress fer 1
    Fer 1, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1903 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/fer 1/product/MedChemExpress
    Average 98 stars, based on 1903 article reviews
    fer 1 - by Bioz Stars, 2026-03
    98/100 stars

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    MedChemExpress fer
    CCK-8 Assay, Establishment of a Caco-2 Cell Monolayer Model;the Effects of MeV on Barrier Function and Inflammatory Response. (A) CCK8 analysis. (B, C) TEER value and ALP activity of monolayer cell model. (D) level of inflammatory factors. (E, F) Western blotting and RT-qPCR analyses of occuldin and ZO-1. Data are presented as mean ± SD. #P<0.05, ## p < 0.01, ###p < 0.001 versus CON group; *p < 0.05, and ***p < 0.001 versus Erastin group. ▴P<0.05, ▴▴p < 0.01, ▴▴▴p < 0.001 <t>versus</t> <t>Fer-1</t> group.
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    MedChemExpress ferrostatin 1 fer 1
    CCK-8 Assay, Establishment of a Caco-2 Cell Monolayer Model;the Effects of MeV on Barrier Function and Inflammatory Response. (A) CCK8 analysis. (B, C) TEER value and ALP activity of monolayer cell model. (D) level of inflammatory factors. (E, F) Western blotting and RT-qPCR analyses of occuldin and ZO-1. Data are presented as mean ± SD. #P<0.05, ## p < 0.01, ###p < 0.001 versus CON group; *p < 0.05, and ***p < 0.001 versus Erastin group. ▴P<0.05, ▴▴p < 0.01, ▴▴▴p < 0.001 <t>versus</t> <t>Fer-1</t> group.
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    Image Search Results


    CCK-8 Assay, Establishment of a Caco-2 Cell Monolayer Model;the Effects of MeV on Barrier Function and Inflammatory Response. (A) CCK8 analysis. (B, C) TEER value and ALP activity of monolayer cell model. (D) level of inflammatory factors. (E, F) Western blotting and RT-qPCR analyses of occuldin and ZO-1. Data are presented as mean ± SD. #P<0.05, ## p < 0.01, ###p < 0.001 versus CON group; *p < 0.05, and ***p < 0.001 versus Erastin group. ▴P<0.05, ▴▴p < 0.01, ▴▴▴p < 0.001 versus Fer-1 group.

    Journal: Frontiers in Immunology

    Article Title: Nrf2/HO-1–dependent inhibition of ferroptosis underlies the antioxidant effects of 5-O-methylvisammioside in colitis

    doi: 10.3389/fimmu.2025.1738408

    Figure Lengend Snippet: CCK-8 Assay, Establishment of a Caco-2 Cell Monolayer Model;the Effects of MeV on Barrier Function and Inflammatory Response. (A) CCK8 analysis. (B, C) TEER value and ALP activity of monolayer cell model. (D) level of inflammatory factors. (E, F) Western blotting and RT-qPCR analyses of occuldin and ZO-1. Data are presented as mean ± SD. #P<0.05, ## p < 0.01, ###p < 0.001 versus CON group; *p < 0.05, and ***p < 0.001 versus Erastin group. ▴P<0.05, ▴▴p < 0.01, ▴▴▴p < 0.001 versus Fer-1 group.

    Article Snippet: The Erastin and Fer-1 were acquired from MedChemExpress (Shanghai, China).

    Techniques: CCK-8 Assay, Activity Assay, Western Blot, Quantitative RT-PCR

    MeV stabilizes oxidative stress levels, Iron metabolic state and mitochondrial status in Caco-2 cells. (A) MDA,GSH and 4-HNE content. (B) MPO activity. (C) Iron metabolic state (D) Mitochondrial morphology observed by TEM (×7.0K; × 20.0K). Data are presented as mean ± SD. ###p < 0.001 versus CON group; **p < 0.01, and ***p < 0.001 versus Erastin group, ▴P<0.05, ▴▴p < 0.01, ▴▴▴p < 0.001 versus Fer-1 group.

    Journal: Frontiers in Immunology

    Article Title: Nrf2/HO-1–dependent inhibition of ferroptosis underlies the antioxidant effects of 5-O-methylvisammioside in colitis

    doi: 10.3389/fimmu.2025.1738408

    Figure Lengend Snippet: MeV stabilizes oxidative stress levels, Iron metabolic state and mitochondrial status in Caco-2 cells. (A) MDA,GSH and 4-HNE content. (B) MPO activity. (C) Iron metabolic state (D) Mitochondrial morphology observed by TEM (×7.0K; × 20.0K). Data are presented as mean ± SD. ###p < 0.001 versus CON group; **p < 0.01, and ***p < 0.001 versus Erastin group, ▴P<0.05, ▴▴p < 0.01, ▴▴▴p < 0.001 versus Fer-1 group.

    Article Snippet: The Erastin and Fer-1 were acquired from MedChemExpress (Shanghai, China).

    Techniques: Activity Assay

    MeV modulates ferroptosis and the Nrf2/HO-1 signaling pathway in Caco-2 cells. (A, B) Western blot and quantification. (C) Relative mRNA levels of indicators. Data are presented as mean ± SD. #P<0.05, ## p < 0.01, ###p < 0.001 versus CON group; *p < 0.05, **p < 0.01, and ***p < 0.001 versus Erastin group; ▴P<0.05, ▴▴p < 0.01, ▴▴▴p < 0.001 versus positive control(Fer-1)group.

    Journal: Frontiers in Immunology

    Article Title: Nrf2/HO-1–dependent inhibition of ferroptosis underlies the antioxidant effects of 5-O-methylvisammioside in colitis

    doi: 10.3389/fimmu.2025.1738408

    Figure Lengend Snippet: MeV modulates ferroptosis and the Nrf2/HO-1 signaling pathway in Caco-2 cells. (A, B) Western blot and quantification. (C) Relative mRNA levels of indicators. Data are presented as mean ± SD. #P<0.05, ## p < 0.01, ###p < 0.001 versus CON group; *p < 0.05, **p < 0.01, and ***p < 0.001 versus Erastin group; ▴P<0.05, ▴▴p < 0.01, ▴▴▴p < 0.001 versus positive control(Fer-1)group.

    Article Snippet: The Erastin and Fer-1 were acquired from MedChemExpress (Shanghai, China).

    Techniques: Western Blot, Positive Control