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costunolide (MedChemExpress)

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MedChemExpress costunolide
Costunolide, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 6 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/costunolide/Costunolide/pm41687519-68-8-33
Average 94 stars, based on 6 article reviews

costunolide - by Bioz Stars, 2026-10

94/100 stars

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Saline:

Article Title: Therapeutic Effect of Costunolide in Autoimmune Hepatitis: Network Pharmacology and Experimental Validation
Article Snippet: .. Costunolide was dissolved in DMSO, then mixed with 40% PEG300 (CAS: 25322-68-3, MCE), 5% Tween 80 (CAS: 9005-65-6, MCE), and normal saline. ..

Article Title: Therapeutic Effect of Costunolide in Autoimmune Hepatitis: Network Pharmacology and Experimental Validation.
Article Snippet: .. Costunolide was dissolved in DMSO, then mixed with 40% PEG300 (CAS: 25322-68-3, MCE), 5% Tween 80 (CAS: 9005-65-6, MCE), and normal saline. ..

Recombinant:

Article Title: Covalently targeting HSP90 with a natural small-molecule costunolide to inhibit necroptosis and ulcerative colitis.
Article Snippet: Background: Necroptosis exacerbates ulcerative colitis (UC) by disrupting intestinal barriers and promoting necroinflammation.. Heat shock protein 90 (HSP90) regulates receptor-interacting protein kinase 1/3 (RIPK1/3) activity through its chaperone function, thereby participating in necroptosis and emerging as a potential therapeutic target for its inhibition in UC therapy.. Costunolide (CTL), a principal sesquiterpene lactone from Aucklandia lappa, has poorly defined mechanisms in UC treatment.

Molecular Weight:

Article Title: Costunolide Plays an Anti-Neuroinflammation Role in Lipopolysaccharide-Induced BV2 Microglial Activation by Targeting Cyclin-Dependent Kinase 2
Article Snippet: .. Costunolide (C15H20O2; molecular weight 232.32), abbreviated as CTL, with purity of 99.84% confirmed by MS and H1NMR data, was purchased from MedChemExpress LLC (Shanghai, China). .. LPS was from Sigma-Aldrich (St. Louis, MO, USA).