cdca (MedChemExpress)

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MedChemExpress cdca
Cdca, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 36 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cdca/Chenodeoxycholic+Acid/pm41974260-57-7-8
Average 95 stars, based on 36 article reviews

cdca - by Bioz Stars, 2026-10

95/100 stars

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In Vitro:

Article Title: Secondary Bile Acids Modified by Odoribacter Splanchnicus Alleviate Colitis by Suppressing Neutrophil Extracellular Trap Formation.
Article Snippet: .. In vitro Analysis of LCA Transformation by O. Splanchnicus: The logarithmic growth stage of O. splanchnicus (OD = 0.1) was inoculated into a medium containing bile acid substrates: CDCA (HY-76847, MCE), CA (HY-N0324, MCE), LCA (L6250, Sigma), and UDCA (HY-13771, MCE). .. The concentration of bile acid in theO. splanchnicus supernatant was measured after 72 h of incubation at 37 °C in an anaerobic workstation using an LC-MS system (Waters Acquity UPLC/AB SCIEX 5500 QQQ-MS).

Transformation Assay:

Cell Culture:

Article Title: Cell migration and adhesion in autophagy-induced damage of human trophoblast cells.
Article Snippet: Introduction: Intrahepatic cholestasis of pregnancy (ICP) is a common pregnancy complication.. It has relatively minor impacts on the mother, but elevated bile acid levels pose severe risks to the fetus, potentially causing adverse pregnancy outcomes such as preterm birth, intrauterine distress, and fetal death.. Autophagy plays a pivotal role in embryonic development, implantation, and pregnancy maintenance.

Recombinant:

Article Title: Microbiota governs host chenodeoxycholic acid glucuronidation to ameliorate bile acid disorder induced diarrhea
Article Snippet: .. In this study, 50 μM and 100 μM CDCA, 10 μM CDCA-3β-glucuronide, and 10 μM UGT1A4 recombinant enzyme (UGT1A4 RE) were used to treat IPEC-J2 for 12–24 h, 10 3 CFU/mL L . reuteri and 50 μM I3C were used to treated IPEC-J2 for 12 h. AHR antagonist (MCE, USA) were used to prevent AHR moving from the cytoplasm to the nucleus. ..

Article Title: Microbiota governs host chenodeoxycholic acid glucuronidation to ameliorate bile acid disorder induced diarrhea.
Article Snippet: .. In this study, 50 μM and 100 μM CDCA, 10 μM CDCA-3β-glucuronide, and 10 μM UGT1A4 recombinant enzyme (UGT1A4 RE) were used to treat IPEC-J2 for 12–24 h, 103 CFU/mL L. reuteri and 50 μM I3C were used to treated IPEC-J2 for 12 h. AHR antagonist (MCE, USA) were used to prevent AHR moving from the cytoplasm to the nucleus. ..

Review